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Journal of clinical oncology, ISSN 1527-7755, 2013, Volume 31, Issue 34, pp. 4333 - 4342
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2013, Volume 288, Issue 36, pp. 25938 - 25949
...(+) precursors, nicotinamide mononucleotide (NMN) and NR, can reverse the FK866-induced cell death, this representing a plausible explanation for the failure of NAMPT inhibition as an anti-cancer therapy... 
NAMPT INHIBITION | IN-VITRO | CYCLIC-ADP-RIBOSE | CHS 828 | ENZYME | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE | CD38 | FK866 | LYMPHOCYTES | 5'-Nucleotidase - genetics | Gene Expression Regulation, Enzymologic - drug effects | Humans | Membrane Glycoproteins - biosynthesis | GPI-Linked Proteins - biosynthesis | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Nicotinamide Phosphoribosyltransferase - antagonists & inhibitors | Neoplasms - genetics | Nicotinamide Phosphoribosyltransferase - metabolism | Piperidines - pharmacology | NAD - biosynthesis | Cell Death - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Acrylamides - pharmacology | Cytokines - genetics | Gene Expression Regulation, Neoplastic - genetics | 5'-Nucleotidase - biosynthesis | NAD - genetics | ADP-ribosyl Cyclase 1 - genetics | Cytokines - metabolism | Gene Silencing | Neoplasms - enzymology | Down-Regulation - drug effects | Down-Regulation - genetics | Membrane Glycoproteins - genetics | Neoplasms - drug therapy | Nicotinamide Phosphoribosyltransferase - genetics | Gene Expression Regulation, Enzymologic - genetics | ADP-ribosyl Cyclase 1 - biosynthesis | Cell Line, Tumor | Cytokines - antagonists & inhibitors | Nicotinamide Mononucleotide - biosynthesis | Nicotinamide Mononucleotide - genetics | GPI-Linked Proteins - genetics | NAD | Cancer Therapy | CD73 | Nicotinamide Riboside | NAD Biosynthesis | Signal Transduction | Cell Death | Nicotinamide Mononucleotide | Nicotinamide
Journal Article
Circulation research, ISSN 1524-4571, 2009, Volume 104, Issue 6, pp. 733 - 741
.... We found that smooth muscle cells (SMCs) gave rise to osteochondrogenic precursor- and chondrocyte-like cells in calcified blood vessels of matrix Gla protein deficient (MGP) mice... 
Vascular calcification | Smooth muscle cells | Genetic fate mapping | Lineage reprogramming | Runx2/Cbfa1 | WALL | CARDIAC & CARDIOVASCULAR SYSTEMS | vascular calcification | ATHEROSCLEROSIS | lineage reprogramming | genetic fate mapping | CARTILAGE | smooth muscle cells | IN-VITRO | DEFICIENT | CALCIFICATION | PERIPHERAL VASCULAR DISEASE | MICE | MUTATIONS | MATRIX-GLA-PROTEIN | HEMATOLOGY | EXPRESSION | Calcinosis - genetics | Vascular Diseases - pathology | Homeodomain Proteins - metabolism | Humans | Myocytes, Smooth Muscle - pathology | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Stem Cells - metabolism | Wnt Proteins - metabolism | Core Binding Factor Alpha 1 Subunit - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Arteries - metabolism | MAP Kinase Signaling System - genetics | Wnt Proteins - genetics | Mice, Mutant Strains | Bone Morphogenetic Protein 2 - metabolism | Calcinosis - metabolism | Myocytes, Smooth Muscle - metabolism | Chondrocytes - metabolism | SOX9 Transcription Factor - metabolism | Bone Morphogenetic Protein 2 - genetics | Chondrocytes - pathology | RNA, Messenger - genetics | Vascular Diseases - genetics | Arteries - pathology | Transcription Factors - genetics | Down-Regulation - genetics | Homeodomain Proteins - genetics | Mice, Knockout | Proteins - genetics | Transcription Factors - metabolism | Animals | Proteins - metabolism | Sp7 Transcription Factor | Stem Cells - pathology | Wnt3 Protein | Mice | Calcinosis - pathology | Vascular Diseases - metabolism | Wnt3A Protein | Cell Dedifferentiation - genetics | SOX9 Transcription Factor - genetics | Core Binding Factor Alpha 1 Subunit - genetics | Cbfa1 | Runx2
Journal Article
Molecular cell, ISSN 1097-2765, 2012, Volume 48, Issue 3, pp. 409 - 421
.... Surprisingly, we also show that the exosome degrades large amounts of tRNA precursors despite the absence... 
II TRANSCRIPTS | RAPID TRANSFER-RNA | OXIDATIVE STRESS | MATURE TRANSFER-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLY(A) POLYMERASE | QUALITY-CONTROL | RIBOSOMAL-RNA | SACCHAROMYCES-CEREVISIAE | BIDIRECTIONAL PROMOTERS | NUCLEAR EXOSOME | CELL BIOLOGY | Introns - genetics | Oligonucleotide Array Sequence Analysis | RNA Processing, Post-Transcriptional | RNA, Transfer - metabolism | Saccharomyces cerevisiae - genetics | RNA, Ribosomal - metabolism | Substrate Specificity | RNA Precursors - genetics | Gene Expression Profiling | Saccharomyces cerevisiae Proteins - genetics | RNA, Ribosomal - genetics | RNA, Small Nucleolar - genetics | RNA, Fungal - metabolism | Saccharomyces cerevisiae - metabolism | Blotting, Northern | RNA, Small Nucleolar - metabolism | Saccharomyces cerevisiae Proteins - metabolism | RNA, Transfer - genetics | Exosome Multienzyme Ribonuclease Complex - metabolism | RNA Precursors - metabolism | RNA, Fungal - genetics | Mutation | Exosome Multienzyme Ribonuclease Complex - genetics | Analysis | Transfer RNA | RNA Precursors | Introns | Quantitative Methods | Biochemistry, Molecular Biology | Genomics | Cellular Biology | RNA, Transfer | Bacteriology | Life Sciences | Microbiology and Parasitology | RNA, Ribosomal | RNA, Small Nucleolar | Saccharomyces cerevisiae Proteins | RNA, Fungal | Subcellular Processes | Exosome Multienzyme Ribonuclease Complex | Molecular biology | Saccharomyces cerevisiae
Journal Article
Annals of neurology, ISSN 0364-5134, 01/2011, Volume 69, Issue 1, pp. 47 - 64
Journal Article
Journal Article
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2011, Volume 364, Issue 3, pp. 215 - 225
Journal Article
PLoS genetics, ISSN 1553-7390, 2015, Volume 11, Issue 2, pp. 1 - 28
The Hippo pathway regulates organ size, stem cell proliferation and tumorigenesis in adult organs. Whether the Hippo pathway influences establishment of stem... 
TISSUE-GROWTH | CANCER ONCOGENE | JAK/STAT PATHWAY | ORGAN SIZE CONTROL | SIGNALING PATHWAY |