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PloS one, ISSN 1932-6203, 12/2010, Volume 5, Issue 12, pp. e14222 - e14222
.... Here the potential of this plant is explored for rapid production of precursors of artemisinin, a sesquiterpenoid compound that is used for malaria treatment... 
acid | reductase | expression system | plants | biosynthesis | annua | yield | tobacco | molecular-cloning | antimalarial-drug artemisinin | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Oligonucleotides - chemistry | Antimalarials - metabolism | Chemistry, Pharmaceutical - methods | Gas Chromatography-Mass Spectrometry | Models, Chemical | Plant Extracts - pharmacology | Tobacco - metabolism | Open Reading Frames | Cytochrome P-450 Enzyme System - metabolism | Mitochondria - metabolism | Oxygen - metabolism | Antimalarials - pharmacology | Artemisinins - pharmacology | Plant Extracts - metabolism | Agrobacterium tumefaciens - metabolism | Plant Leaves - metabolism | Tobacco - genetics | Drug Design | Artemisinins - metabolism | Plant Proteins - metabolism | Oxidases | Malaria | Transferases | Genetic aspects | Fermentation | Chemical synthesis | Health aspects | Drugs | Biotechnology | Metabolomics | Dehydrogenases | Laboratories | Genes | Artemisinin | Alcohol | Biosynthesis | Drug resistance | Proteins | Engineering | Leaves | Parasitic diseases | Precursors | Physiology | Oxidation | Trends | Vector-borne diseases | Plants (botany) | Metabolism | Chromatography | Tobacco | Acids | Headspace | Growth hormones | Scientific imaging | Infiltration | Mass spectrometry | Pharmaceuticals | Reductase | Index Medicus
Journal Article
Nature reviews. Molecular cell biology, ISSN 1471-0080, 09/2016, Volume 18, Issue 1, pp. 18 - 30
Journal Article
Cell metabolism, ISSN 1550-4131, 06/2012, Volume 15, Issue 6, pp. 838 - 847
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 09/2010, Volume 330, Issue 6000, pp. 70 - 74
Taxol (paclitaxel) is a potent anticancer drug first isolated from the Taxus brevifolia Pacific yew tree. Currently, cost-efficient production of Taxol and its... 
Enzymes | Cellular metabolism | Terpenoids | Chemical engineering | Bioreactors | Plasmids | REPORTS | Operons | Biosynthesis | Indoles | Streams | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Metabolomics | NADPH-Ferrihemoprotein Reductase - genetics | Erythritol - analogs & derivatives | Cytochrome P-450 Enzyme System - metabolism | Taxoids - metabolism | Organophosphorus Compounds - metabolism | Recombinant Fusion Proteins - metabolism | Farnesyltranstransferase - metabolism | Escherichia coli K12 - metabolism | Hemiterpenes - metabolism | Indoles - metabolism | Terpenes - metabolism | Erythritol - metabolism | Isomerases - genetics | Diterpenes - metabolism | NADPH-Ferrihemoprotein Reductase - metabolism | Paclitaxel - biosynthesis | Oxidation-Reduction | Fermentation | Taxus - enzymology | Metabolic Networks and Pathways - genetics | Genetic Engineering | Sugar Phosphates - metabolism | Farnesyltranstransferase - genetics | Cytochrome P-450 Enzyme System - genetics | Isomerases - metabolism | Escherichia coli K12 - genetics | Alkenes - metabolism | Escherichia coli K12 - enzymology | Physiological aspects | Research | Health aspects | Escherichia coli | Biological transport | Biochemistry | Pharmacology | E coli | Drugs | Pathways | Searching | Taxol | Modules | Modular | Pacific yew | Optimization | Index Medicus
Journal Article