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Biochemistry, ISSN 0006-2960, 03/2014, Volume 53, Issue 8, pp. 1296 - 1301
Journal Article
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7610, pp. 169 - 172
Ebola viruses (EBOVs) are responsible for repeated outbreaks of fatal infections, including the recent deadly epidemic in West Africa. There are currently no... 
SYSTEM | NIEMANN-PICK C1 | ENTRY | CHOLESTEROL | SMALL-MOLECULE INHIBITORS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ANTIBODY | RECEPTOR | INFECTION | HIV-1 VIRION FUSION | Temperature | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Antiviral Agents - metabolism | Endosomes - metabolism | Protein Subunits - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Ebolavirus - drug effects | Ibuprofen - chemistry | Antiviral Agents - chemistry | Endosomes - drug effects | Viral Envelope Proteins - metabolism | Conserved Sequence | Marburgvirus - chemistry | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Binding Sites | Membrane Fusion - drug effects | Toremifene - metabolism | Toremifene - pharmacology | Cell Line | Antiviral Agents - pharmacology | Ibuprofen - pharmacology | Models, Molecular | Protein Structure, Quaternary - drug effects | Ibuprofen - metabolism | Virus Attachment - drug effects | Ebolavirus - chemistry | Viral Envelope Proteins - antagonists & inhibitors | Protein Stability - drug effects | Viral Envelope Proteins - chemistry | Hydrophobic and Hydrophilic Interactions | Protein Binding | Ligands | Protein Subunits - chemistry | Toremifene - chemistry | Ebola virus | Glycoproteins | Host-virus relationships | Observations | Health aspects | Drug interactions | Drug therapy | Binding sites | Viral infections | Crystal structure
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 02/2007, Volume 14, Issue 2, pp. 230 - 239
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2009, Volume 284, Issue 40, pp. 27384 - 27392
Journal Article
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7577, pp. 245 - 248
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2005, Volume 280, Issue 7, pp. 5892 - 5901
Alzheimer's disease (AD) involves amyloid beta (Abeta) accumulation, oxidative damage, and inflammation, and risk is reduced with increased antioxidant and... 
PROTEIN | CLINICAL-TRIAL | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | ALZHEIMERS-DISEASE | CONGO RED | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | CHEMOPREVENTIVE AGENT | NF-KAPPA-B | CACHE COUNTY | TRANSGENIC MICE | Protein Denaturation - drug effects | Peptide Fragments - toxicity | Benzoates - chemistry | Curcumin - chemistry | Humans | Naproxen - pharmacology | Plaque, Amyloid - chemistry | Curcumin - metabolism | Pyridazines - pharmacology | Alzheimer Disease - pathology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Brain - metabolism | Biphenyl Compounds - pharmacology | Protein Binding - drug effects | Amyloid beta-Peptides - metabolism | Thiazoles | Blood-Brain Barrier - physiology | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Biphenyl Compounds - chemistry | Peptide Fragments - metabolism | Ibuprofen - pharmacology | Plaque, Amyloid - pathology | Amyloid beta-Peptides - toxicity | Curcumin - pharmacology | Solubility | Mice, Transgenic | Protein Structure, Quaternary - drug effects | Blood-Brain Barrier - drug effects | Plaque, Amyloid - genetics | Pyridazines - chemistry | Brain - drug effects | Amyloid beta-Peptides - antagonists & inhibitors | Peptide Fragments - chemistry | Animals | Congo Red | Peptide Fragments - antagonists & inhibitors | Alzheimer Disease - metabolism | Benzoates - pharmacology | Brain - pathology | Cell Line, Tumor | Diamines - chemistry | Diamines - pharmacology | Plaque, Amyloid - metabolism | Mice | Amyloid beta-Peptides - chemistry | Alzheimer Disease - genetics
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 09/2006, Volume 15, Issue 18, pp. 2743 - 2751
Huntington's disease (HD) is a progressive neurodegenerative disorder for which only symptomatic treatments of limited effectiveness are available. Preventing... 
NEURONAL INTRANUCLEAR INCLUSIONS | PATHOGENESIS | ANTIBODIES | INHIBITION | PROTEIN AGGREGATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | POLYPHENOL | DYSFUNCTION | POLYGLUTAMINE AGGREGATION | IDENTIFICATION | DROSOPHILA | Camellia sinensis - chemistry | Exons | Saccharomyces cerevisiae - genetics | Humans | Multiprotein Complexes | Protein Conformation - drug effects | Saccharomyces cerevisiae - drug effects | Drosophila melanogaster - genetics | Recombinant Fusion Proteins - drug effects | Nerve Tissue Proteins - chemistry | Photoreceptor Cells, Invertebrate - drug effects | Microscopy, Atomic Force | Nuclear Proteins - drug effects | Phytotherapy | Catechin - pharmacology | Huntington Disease - drug therapy | Nuclear Proteins - genetics | Motor Neurons - drug effects | Animals, Genetically Modified | Protein Structure, Quaternary - drug effects | Recombinant Fusion Proteins - chemistry | Nuclear Proteins - chemistry | Huntington Disease - metabolism | Nerve Tissue Proteins - drug effects | Nerve Tissue Proteins - genetics | Protein Folding | Saccharomyces cerevisiae - chemistry | Huntingtin Protein | Animals | Models, Biological | Huntington Disease - genetics | Recombinant Fusion Proteins - genetics | Catechin - analogs & derivatives | Mutation | In Vitro Techniques | Nerve Degeneration - drug therapy
Journal Article