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Biometals, ISSN 0966-0844, 12/2011, Volume 24, Issue 6, pp. 993 - 1004
Life Sciences | Biochemistry, general | Protein tyrosine phosphatases | Microbiology | Fluorescence | Plant Physiology | Copper complex | Inhibition | Pharmacology/Toxicology | Medicine/Public Health, general | Cell Biology | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Humans | Protein Tyrosine Phosphatases - metabolism | Structure-Activity Relationship | Benzimidazoles - chemistry | Enzyme Inhibitors - chemical synthesis | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - chemistry | Protein Tyrosine Phosphatases - antagonists & inhibitors | Protein Tyrosine Phosphatases - chemistry | Protein Tyrosine Phosphatases - genetics | Protein Tyrosine Phosphatases, Non-Receptor - chemistry | Copper - chemistry | Enzyme Inhibitors - chemistry | Protein Tyrosine Phosphatases, Non-Receptor - genetics | Copper - metabolism | Molecular Structure | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - chemistry | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - chemistry | Enzyme Inhibitors - metabolism | Benzimidazoles - chemical synthesis | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - antagonists & inhibitors | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - antagonists & inhibitors | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - chemistry | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Spectrum Analysis - methods | Benzimidazoles - metabolism | Protein Tyrosine Phosphatases, Non-Receptor - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - antagonists & inhibitors | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - antagonists & inhibitors | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - genetics | Protein Tyrosine Phosphatases, Non-Receptor - antagonists & inhibitors | Tyrosine | Phosphatases | Ionization | Analysis | Phenols | T cells | Mass spectrometry | Proteins | Enzymes | Cellular biology | Copper | Spectroscopy | Inhibitors | Derivatives | Index Medicus
Journal Article
Nature immunology, ISSN 1529-2908, 05/2012, Volume 13, Issue 5, pp. 439 - 447
Life Sciences & Biomedicine | Immunology | Science & Technology | Antigens, CD - immunology | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - immunology | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - immunology | Humans | Autoimmunity - genetics | NK Cell Lectin-Like Receptor Subfamily K - immunology | Protein Tyrosine Phosphatases - metabolism | Leukocyte Common Antigens - immunology | Signal Transduction - immunology | Protein Tyrosine Phosphatases - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 22 - immunology | Signaling Lymphocytic Activation Molecule Family Member 1 | Autoimmunity - immunology | Receptors, Antigen, T-Cell - immunology | Lymphocyte Activation | Protein Tyrosine Phosphatase, Non-Receptor Type 22 - genetics | Receptor-Like Protein Tyrosine Phosphatases, Class 3 - immunology | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - genetics | Receptors, Cell Surface - immunology | Receptors, Antigen, B-Cell - immunology | Animals | Lymphocytes - enzymology | Mice | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - deficiency | Protein Tyrosine Phosphatase, Non-Receptor Type 12 - immunology | Tyrosine | Autoimmunity | Phosphatases | Immune response | Lymphocytes | Physiological aspects | Research | Properties | Index Medicus
Journal Article
Journal of inorganic biochemistry, ISSN 0162-0134, 2011, Volume 105, Issue 9, pp. 1138 - 1147
PTPs | Inhibitor | Selectivity | Dinuclear copper complexes | Biochemistry & Molecular Biology | Physical Sciences | Chemistry, Inorganic & Nuclear | Chemistry | Life Sciences & Biomedicine | Science & Technology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Escherichia coli | Humans | Substrate Specificity | Crystallography, X-Ray | Enzyme Inhibitors - chemical synthesis | Spectrometry, Mass, Electrospray Ionization | Transformation, Bacterial | X-Ray Diffraction | Protein Tyrosine Phosphatases, Non-Receptor - genetics | Acids, Heterocyclic - chemical synthesis | Cloning, Molecular | Copper - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - genetics | Acids, Heterocyclic - pharmacology | Recombinant Proteins - metabolism | Recombinant Proteins - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - antagonists & inhibitors | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - antagonists & inhibitors | Models, Molecular | Recombinant Proteins - genetics | Chelating Agents - pharmacology | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - genetics | Potentiometry | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Signal Transduction - drug effects | Protein Tyrosine Phosphatases, Non-Receptor - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - antagonists & inhibitors | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - antagonists & inhibitors | Ligands | Signal Transduction - physiology | Kinetics | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - genetics | Chelating Agents - chemical synthesis | Protein Tyrosine Phosphatases, Non-Receptor - antagonists & inhibitors | Tyrosine | Phenols | Phosphatases | Analysis | Index Medicus
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 03/2013, Volume 123, Issue 3, pp. 1044 - 1065
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Phosphorylation | Humans | Transcriptome | MicroRNAs - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Programmed Cell Death 1 Receptor - physiology | Signal Transduction - immunology | ZAP-70 Protein-Tyrosine Kinase - metabolism | Cell Line | HLA-A2 Antigen - immunology | Immunotherapy, Adoptive | Antigens, Neoplasm - immunology | Lymphocyte Activation | Programmed Cell Death 1 Receptor - metabolism | Membrane Proteins - immunology | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Receptors, Antigen, T-Cell, alpha-beta - genetics | CD8-Positive T-Lymphocytes - physiology | CD8-Positive T-Lymphocytes - enzymology | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Down-Regulation - immunology | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - antagonists & inhibitors | Antimony Sodium Gluconate - pharmacology | Protein Binding | MicroRNAs - genetics | Protein Processing, Post-Translational | Receptors, Antigen, T-Cell, alpha-beta - metabolism | CD8-Positive T-Lymphocytes - immunology | Programmed Cell Death 1 Receptor - genetics | Antigen receptors, T cell | Receptors | Phosphatases | Physiological aspects | Cellular immunity | Genetic aspects | Research | Gene expression | T cells | Index Medicus | Abridged Index Medicus
Journal Article
Nature medicine, ISSN 1078-8956, 07/2018, Volume 24, Issue 7, pp. 954 - 960
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Pancreatic Neoplasms - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Lung Neoplasms - metabolism | Pancreatic Neoplasms - pathology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Lung Neoplasms - pathology | Mutation - genetics | Carcinogenesis - metabolism | Disease Progression | Carcinogenesis - pathology | Mitogen-Activated Protein Kinase Kinases - metabolism | Animals | Protein Kinase Inhibitors - therapeutic use | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - deficiency | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | Tyrosine | Care and treatment | Cellular signal transduction | Genetic aspects | Research | Gene expression | Cancer | Adenocarcinoma | Animal models | Xenotransplantation | Lung cancer | Phosphatase | Carcinogenesis | K-Ras protein | Proteins | Signal transduction | Carcinogens | Allosteric properties | Clonal deletion | Organoids | Dependence | Xenografts | Protein-tyrosine kinase receptors | Inhibition | Pancreas | Protein-tyrosine kinase | MAP kinase | Tumor cell lines | Signaling | Tumors | Protein-tyrosine-phosphatase | Index Medicus
Journal Article
Cancer letters, ISSN 0304-3835, 2013, Volume 345, Issue 1, pp. 140 - 148
Hematology, Oncology and Palliative Medicine | Capillarisin | PTP | STAT3 | Multiple myeloma | Apoptosis | Life Sciences & Biomedicine | Oncology | Science & Technology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Apoptosis - drug effects | Humans | Multiple Myeloma - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - biosynthesis | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Multiple Myeloma - drug therapy | Multiple Myeloma - pathology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - biosynthesis | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Signal Transduction - drug effects | Cell Line, Tumor | Enzyme Induction - drug effects | Cell Proliferation - drug effects | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - genetics | Chromones - pharmacology | Multiple Myeloma - genetics | STAT3 Transcription Factor - metabolism | Tyrosine | Phenols | Phosphatases | Vascular endothelial growth factor | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 09/2018, Volume 132, Issue 13, pp. 1413 - 1425
THROMBOCYTOPENIA | ACTIVATION | MICE | PROTEIN | PHOSPHORYLATION | Life Sciences & Biomedicine | Hematology | Science & Technology | Blood Platelets - pathology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Phosphorylation | Receptors, Immunologic - chemistry | Signal Transduction | Mice, Inbred C57BL | Homeostasis | Models, Molecular | Mice, Transgenic | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - chemistry | Thrombocytopenia - pathology | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - chemistry | Thrombocytopenia - metabolism | Protein Interaction Maps | src Homology Domains | Thrombocytopenia - genetics | Point Mutation | Animals | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Blood Platelets - metabolism | Mice | Receptors, Immunologic - genetics | Binding Sites | Receptors, Immunologic - metabolism | 37 | 35 | Platelets and Thrombopoiesis
Journal Article
The FEBS journal, ISSN 1742-464X, 01/2013, Volume 280, Issue 2, pp. 346 - 378
kinase | tyrosine phosphatase | cancer | drug discovery | signal transduction | diabetes | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Pregnancy | Catalytic Domain | Phosphorylation | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism | Signal Transduction | Humans | Models, Molecular | Crystallography, X-Ray | Female | Placenta - enzymology | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - chemistry | Tyrosine | Enzymes | Phosphatases | Home economics | Physiological aspects | Phenols | Hypoglycemic agents | Proteins | Signal transduction | Biochemistry | Index Medicus
Journal Article