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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2019, Volume 514, Issue 1, pp. 224 - 230
Protein synthesis and degradation balance have a crucial role in maintenance of cellular homeostasis and function. The ubiquitin-proteasome system is one of... 
Hsp90 | Proteasome activation | Hsp70 | Proteasome | Protein synthesis inhibition
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2015, Volume 125, Issue 6, pp. 2279 - 2292
Glycosphingolipids (GSLs) are essential constituents of cell membranes and lipid rafts and can modulate signal transduction events. The contribution of GSLs in... 
MULTIPLE-MYELOMA | SIGNAL-TRANSDUCTION | MEDICINE, RESEARCH & EXPERIMENTAL | ALPHA MIP-1-ALPHA | CELL LINE HL-60 | RECEPTOR ACTIVATOR | PROTEIN 1-ALPHA | N-BUTYLDEOXYNOJIRIMYCIN | MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA | KAPPA-B LIGAND | GAUCHER-DISEASE | RANK Ligand - metabolism | Membrane Microdomains - metabolism | Glycosphingolipids - genetics | Insulin-Like Growth Factor I - genetics | Glucosyltransferases - metabolism | src-Family Kinases - metabolism | 1-Deoxynojirimycin - analogs & derivatives | Female | TNF Receptor-Associated Factor 6 - genetics | Osteolysis - pathology | Glucosyltransferases - genetics | Glucosyltransferases - antagonists & inhibitors | Cell Line | Osteoclasts - pathology | Osteolysis - genetics | Glycosphingolipids - biosynthesis | Glycoside Hydrolase Inhibitors - pharmacology | Multiple Myeloma - metabolism | Osteoclasts - metabolism | Osteolysis - metabolism | Mice, Knockout | RANK Ligand - genetics | 1-Deoxynojirimycin - pharmacology | Multiple Myeloma - pathology | Animals | TNF Receptor-Associated Factor 6 - metabolism | Mice | src-Family Kinases - genetics | Membrane Microdomains - pathology | Insulin-Like Growth Factor I - metabolism | Membrane Microdomains - genetics | Multiple Myeloma - genetics | Enzymes | Statistical analysis | Biomedical research | Colleges & universities | Multiple myeloma | Lipids | Biosynthesis | Bone diseases | Bone Biology | Oncology
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2016, Volume 44, Issue 5, pp. 2439 - 2450
Journal Article
Journal Article
Journal Article
PLoS Genetics, ISSN 1553-7390, 07/2018, Volume 14, Issue 7, p. e1007520
Across organisms, manipulation of biosynthetic capacity arrests development early in life, but can increase health- and lifespan post-developmentally. Here we... 
TRANSLATIONAL INHIBITION | LIFE-SPAN | LONGEVITY | METALLOTHIONEIN | GENE | RNA | MITOCHONDRIAL METABOLISM | GENETICS & HEREDITY | RESISTANCE | S6 KINASE | RESTRICTION | AMP-Activated Protein Kinases - metabolism | Longevity - drug effects | Aging - drug effects | Protein Biosynthesis - physiology | Caenorhabditis elegans Proteins - metabolism | Ribosomes - metabolism | Caenorhabditis elegans - physiology | RNA Interference | Pharynx - physiology | Protein Biosynthesis - genetics | Protein Synthesis Inhibitors - pharmacology | Subcutaneous Tissue - metabolism | Gene Expression Regulation, Developmental - physiology | Signal Transduction - genetics | Longevity - genetics | Feeding Behavior - physiology | Biological Evolution | Animals | Aging - physiology | Ribosomes - genetics | Ribosomes - drug effects | Protein Biosynthesis - drug effects | Larva - physiology | Caenorhabditis elegans Proteins - genetics | AMP-Activated Protein Kinases - genetics | Physiological aspects | Caenorhabditis elegans | Microbiological research | Protein biosynthesis | Research | Protein kinases | Oxidative stress | Biosynthesis | Kinases | Proteins | Animal reproduction | Aging | Evolution | Xenobiotics | Worms | Pathogens | Phenotypes | Cell survival | RNA-mediated interference | Translation initiation | Pharynx | Heavy metals | Cycloheximide | Gerontology | Life span | Protein synthesis | Nematodes | Adults | Respiration | Binding sites
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e55194
Fetal growth is critically dependent on energy metabolism in the placenta, which drives active exchange of nutrients. Placental oxygen levels are therefore... 
OXYGEN | SKELETAL-MUSCLE | HIGH-ALTITUDE HYPOXIA | OXIDATIVE STRESS | RESPIRATION | MULTIDISCIPLINARY SCIENCES | METABOLIC ADAPTATION | NITRIC-OXIDE | PREECLAMPSIA | GROWTH RESTRICTION | MICRORNA-210 | Cell Line | Humans | Alkyl and Aryl Transferases - metabolism | MicroRNAs - metabolism | MicroRNAs - pharmacology | Blotting, Western | Oxygen - metabolism | Electron Transport Complex IV - metabolism | Hypoxia - metabolism | Pregnancy | Placenta - physiopathology | Analysis of Variance | Electron Transport Chain Complex Proteins - antagonists & inhibitors | Female | Hypoxia - physiopathology | Iron-Sulfur Proteins - metabolism | Membrane Proteins - metabolism | Cell Culture Techniques | Energy Metabolism - physiology | Real-Time Polymerase Chain Reaction | Altitude | Oxidases | MicroRNA | Growth | Fetus | Protein biosynthesis | Electron transport | Cytochrome | High altitude | Oxidative stress | Energy metabolism | Neurosciences | Target recognition | Cytochrome-c oxidase | Iron | Mitochondrial DNA | Proteins | Electron transport chain | Mitochondria | Rodents | Cell cycle | Fibroblasts | Nutrients | Physiology | Inhibition | Sulfur | Oxygen | Fetuses | MiRNA | Metabolism | Sea level | Ribonucleic acid--RNA | Musculoskeletal system | Placenta | Protein synthesis | MicroRNAs | Nitric oxide | Preeclampsia | Hypoxia | Respiration | Cancer | Apoptosis | RNA | miRNA | Ribonucleic acid
Journal Article