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ACCOUNTS OF CHEMICAL RESEARCH, ISSN 0001-4842, 03/2019, Volume 52, Issue 3, pp. 818 - 832
Proteins are well-known to undergo a variety of post-translational modifications (PTMs). One such PTM is citrullination, an arginine modification that is... 
IN-VITRO | DESIGN | INHIBITION | PROTEIN-ARGININE-DEIMINASE-4 PAD4 | SCREEN | HALOACETAMIDINE | CALCIUM | CL-AMIDINE | INACTIVATORS | SUFFICIENT | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
ACS Applied Materials & Interfaces, ISSN 1944-8244, 01/2017, Volume 9, Issue 1, pp. 152 - 158
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 02/2015, Volume 58, Issue 3, pp. 1337 - 1344
Protein arginine deiminases (PADs) catalyze the post-translational hydrolysis of arginine residues to form citrulline. This once obscure modification is now... 
NEUTROPHIL EXTRACELLULAR TRAPS | IN-VITRO | IDENTIFY | CHEMISTRY, MEDICINAL | CITRULLINATED PROTEINS | PROTEIN-ARGININE-DEIMINASE-4 PAD4 | MECHANISM | PEPTIDYLARGININE DEIMINASE | CL-AMIDINE | TETRACYCLINE | MURINE MODELS
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2018, Volume 9, Issue 10, pp. 1013 - 1018
Protein arginine deiminase 4 (PAD4) is a calcium-dependent enzyme that catalyzes the conversion of arginine to citrulline within target proteins. Dysregulation... 
inflammatory disease | mechanism-based inhibitor | Protein arginine deiminase | rheumatoid arthritis | citrullination | RHEUMATOID-ARTHRITIS | METHYLATION | ACTIVATION | DESIGN | CHEMISTRY, MEDICINAL | NEUTROPHILS | EPIGENETIC REGULATION | TISSUES | EXPRESSION | BLOOD
Journal Article
Journal Article
Theoretical Chemistry Accounts, ISSN 1432-881X, 2012, Volume 131, Issue 12, pp. 1 - 14
Journal Article
Journal Article
ChemBioChem, ISSN 1439-4227, 09/2018, Volume 19, Issue 17, pp. 1806 - 1809
Protein arginine deiminases (PADs) have recently emerged at the forefront of drug‐discovery programs for several human disorders. Despite this, a precise... 
autoimmune diseases | protein citrullination | post-translational modifications | protein arginine deiminase | activity-based probes | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITOR | DISCOVERY | Arginine | Investigations | Proteins | Proteomics | Biology | Drug discovery | Drug development | Probes
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2003, Volume 34, Issue 4, pp. 395 - 402
Journal Article