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The New England Journal of Medicine, ISSN 0028-4793, 08/2017, Volume 377, Issue 9, pp. 829 - 838
Alectinib, a potent ALK tyrosine kinase inhibitor, was more effective and somewhat less toxic than crizotinib when used as primary therapy in patients with ALK... 
RESISTANT | MEDICINE, GENERAL & INTERNAL | MODELS | ANTITUMOR-ACTIVITY | INHIBITOR ALECTINIB | CHEMOTHERAPY | Lung Neoplasms - drug therapy | Pyrazoles - therapeutic use | Follow-Up Studies | Lung Neoplasms - mortality | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Protein Kinase Inhibitors - adverse effects | Central Nervous System Neoplasms - secondary | Young Adult | Pyridines - adverse effects | Anaplastic Lymphoma Kinase | Antineoplastic Agents - adverse effects | Aged, 80 and over | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Adult | Female | Receptor Protein-Tyrosine Kinases - analysis | Pyrazoles - adverse effects | Pyridines - therapeutic use | Crizotinib | Carbazoles - adverse effects | Kaplan-Meier Estimate | Carcinoma, Non-Small-Cell Lung - mortality | Disease-Free Survival | Animals | Piperidines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Piperidines - adverse effects | Intention to Treat Analysis | Carbazoles - therapeutic use | Carcinoma, Non-Small-Cell Lung - drug therapy | Central Nervous System Neoplasms - drug therapy | Drugs | Care and treatment | Analysis | Comparative analysis | Lung cancer, Non-small cell | Health aspects | Systemic diseases | Toxicity | Lung cancer | Central nervous system | Non-small cell lung carcinoma | Oncology | Nervous system | Metastasis | Radiation therapy | Patients | Lymphoma | Cancer therapies | Survival | Mutation | Protein-tyrosine kinase | Drug dosages | Tumors | Index Medicus | Abridged Index Medicus
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2014, Volume 106, Issue 2, p. djt378
Journal Article
Cancer Cell, ISSN 1535-6108, 2010, Volume 18, Issue 3, pp. 244 - 257
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 2, pp. 234 - 242
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2018, Volume 378, Issue 8, pp. 731 - 739
Journal Article
Gastroenterology, ISSN 0016-5085, 2012, Volume 142, Issue 4, pp. 1021 - 1031.e15
Background & Aims Cholangiocarcinoma is a heterogeneous disease with a poor outcome that accounts for 5%−10% of primary liver cancers. We characterized its... 
Gastroenterology and Hepatology | CCA | Gene Expression | Hepatic | Genetic Analysis | SURVIVAL | INTRAHEPATIC CHOLANGIOCARCINOMA | PHASE-II | RECEPTOR | EXPRESSION PROFILES | BREAST-CANCER | BILIARY CANCER | LUNG-CANCER | HEPATOCELLULAR-CARCINOMA | MUTATIONS | GASTROENTEROLOGY & HEPATOLOGY | Immunohistochemistry | Receptor, Epidermal Growth Factor - genetics | Proto-Oncogene Proteins p21(ras) | Oligonucleotide Array Sequence Analysis | Humans | Middle Aged | Tumor Microenvironment | Male | Bile Duct Neoplasms - enzymology | Time Factors | Bile Duct Neoplasms - genetics | Cholangiocarcinoma - enzymology | Precision Medicine | Genetic Predisposition to Disease | Risk Assessment | Risk Factors | ras Proteins - antagonists & inhibitors | Survival Rate | Blotting, Western | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Phenotype | Belgium | Cell Line, Tumor | Cholangiocarcinoma - genetics | Mutation | Quinazolines - pharmacology | Trastuzumab | Cluster Analysis | Protein-Tyrosine Kinases - antagonists & inhibitors | ras Proteins - genetics | Prognosis | United States | Laser Capture Microdissection | Molecular Targeted Therapy | Patient Selection | Protein-Tyrosine Kinases - genetics | Antibodies, Monoclonal, Humanized - pharmacology | Female | Antineoplastic Agents - pharmacology | Bile Duct Neoplasms - drug therapy | Proto-Oncogene Proteins - antagonists & inhibitors | Bile Ducts, Intrahepatic - pathology | Cholangiocarcinoma - mortality | Kaplan-Meier Estimate | Proportional Hazards Models | Gene Expression Profiling - methods | Proto-Oncogene Proteins - genetics | Chi-Square Distribution | Bile Ducts, Intrahepatic - enzymology | Cholangiocarcinoma - pathology | Cholangiocarcinoma - drug therapy | Proto-Oncogene Proteins B-raf - genetics | Bile Duct Neoplasms - mortality | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Aged | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Bile Duct Neoplasms - pathology | Protein-Tyrosine Kinases - analysis | Queensland | Tyrosine | Genes | Amino acids | Transforming growth factors | Gene expression | Liver cancer | Epidermal growth factor | Analysis | Phenols | Genetic research | Genetic aspects | Health aspects | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 1, p. e15640
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2012, Volume 13, Issue 10, pp. 1011 - 1019
Journal Article
Nature Genetics, ISSN 1061-4036, 11/2000, Volume 26, Issue 3, pp. 283 - 289