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by Marouli, Eirini and Graff, Mariaelisa and Medina-Gomez, Carolina and Lo, Ken Sin and Wood, Anew R and Kjaer, Troels R and Fine, Rebecca S and Lu, Yingchang and Schurmann, Claudia and Highland, Heather M and Rüeger, Sina and Thorleifsson, Gudmar and Justice, Anne E and Lamparter, David and Stirrups, Kathleen E and Turcot, Valérie and Young, Kristin L and Winkler, Thomas W and Esko, Tõnu and Karaderi, Tugce and Locke, Adam E and Masca, Nicholas G. D and Ng, Maggie C. Y and Mudgal, Poorva and Rivas, Manuel A and Vedantam, Sailaja and Mahajan, Anubha and Guo, Xiuqing and Abecasis, Goncalo and Aben, Katja K and Adair, Linda S and Alam, Dewan S and Albrecht, Eva and Allin, Kristine H and Allison, Matthew and Amouyel, Philippe and Appel, Emil V and Arveiler, Dominique and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Banas, Bernhard and Bang, Lia E and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bonnycastle, Lori L and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Burt, Amber A and Butterworth, Adam S and Carey, David J and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Cocca, Massimiliano and Collins, Francis S and Cook, James P and Corley, Janie and Galbany, Jordi Corominas and Cox, Amanda J and Cuellar-Partida, Gabriel and Danesh, John and Davies, Gail and de Bakker, Paul I. W and de Borst, Gert J and de Denus, Simon and de Groot, Mark C. H and de Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and den Hollander, Anneke I and Dennis, Joe G and Di Angelantonio, Emanuele and nos, Fotios and Du, Mengmeng and Dunning, Alison M and Easton, Douglas F and Ebeling, Tapani and Edwards, Todd L and Ellinor, Patrick T and Elliott, Paul and Evangelou, Evangelos and Farmaki, Aliki-Eleni and Faul, Jessica D and ... and EPIC-CVD Consortium and GoT2D Genes Consortium and MAGIC Investigators and Global Lipids Genetics Consortium and EPIC-InterAct Consortium and ReproGen Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium and CHD Exome+ Consortium and The EPIC-InterAct Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2017, Volume 542, Issue 7640, pp. 186 - 190
Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so... 
MULTIDISCIPLINARY SCIENCES | MISSING HERITABILITY | GENETIC ARCHITECTURE | INTERLEUKIN-11 | MICE | MUTATIONS | GENOME-WIDE ASSOCIATION | Cell Adhesion Molecules - genetics | Gene Frequency - genetics | Humans | Glycoproteins - metabolism | Male | Intercellular Signaling Peptides and Proteins - metabolism | Hedgehog Proteins - genetics | Proteolysis | NADPH Oxidases - genetics | Adult | Female | Interleukin-11 Receptor alpha Subunit - genetics | Somatomedins - metabolism | Glycosaminoglycans - biosynthesis | Glycoproteins - genetics | Multifactorial Inheritance - genetics | Procollagen N-Endopeptidase - genetics | Intercellular Signaling Peptides and Proteins - genetics | Interferon Regulatory Factors - genetics | Proteoglycans - biosynthesis | NADPH Oxidase 4 | Body Height - genetics | Genome, Human - genetics | Phenotype | Receptors, Androgen - genetics | Alleles | Genetic Variation - genetics | Pregnancy-Associated Plasma Protein-A - metabolism | ADAMTS Proteins - genetics | Stature | Genetic aspects | Observations | Genetic variation | Studies | Datasets | Disease | Genes | Deoxyribonucleic acid--DNA | Index Medicus | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Health Sciences
Journal Article
Journal Article
P L o S Genetics (Print), ISSN 1553-7390, 04/2011, Volume 7, Issue 4, pp. e1001372 - e1001372
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 505, Issue 7482, pp. 212 - 217
Non-small-cell lung cancer (NSCLC) is the most prevalent histological cancer subtype worldwide(1). As the majority of patients present with invasive,... 
TRANSFORMATION | MESSENGER-RNAS | OVEREXPRESSION | TGF-BETA | GENE | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | LET-7 | INHIBITOR | BINDING | EXPRESSION DATA | Receptors, Transforming Growth Factor beta - genetics | Cell Proliferation | Humans | Lung Neoplasms - pathology | MicroRNAs - metabolism | Proteoglycans - deficiency | RNA Isoforms - metabolism | HMGA2 Protein - genetics | Gene Expression Regulation, Neoplastic - genetics | Disease Models, Animal | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Argonaute Proteins - metabolism | RNA Isoforms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Proteoglycans - biosynthesis | Disease Progression | Neoplasm Metastasis - genetics | Receptors, Transforming Growth Factor beta - biosynthesis | Animals | Cell Line, Tumor | Binding, Competitive - genetics | Mice | MicroRNAs - genetics | Transcription, Genetic - genetics | Neoplasm Invasiveness - genetics | Transforming Growth Factor beta - metabolism | Proteoglycans - genetics | Receptors, Transforming Growth Factor beta - deficiency | RNA sequencing | Gene targeting | Development and progression | Genetic aspects | Genetic transcription | Lung cancer, Non-small cell | Identification and classification | Methods | Proteins | Hypothesis testing | Survival analysis | Hypotheses | Transplants & implants | Lung cancer | Genomes | Tumorigenesis | Mutation | Gene expression | Tumors | Index Medicus
Journal Article
Hepatology, ISSN 0270-9139, 09/2013, Volume 58, Issue 3, pp. 966 - 975
Journal Article
PLoS Genetics, ISSN 1553-7390, 03/2011, Volume 7, Issue 3, pp. e1001332 - e1001332
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 3/2003, Volume 160, Issue 5, pp. 753 - 767
Cell migration and invasion are fundamental components of tumor cell metastasis. Increased focal adhesion kinase (FAK) expression and tyrosine phosphorylation... 
Cell motility | Phosphorylation | Phenotypes | Cell growth | Cell cycle | Biological invasions | Antibodies | Pseudopodia | Focal adhesions | Cells | FAK | Motility | Src | JNK | Invasion | CARCINOMA-CELLS | TYROSINE PHOSPHORYLATION | JUN NH2-TERMINAL KINASE | NULL CELLS | CELL BIOLOGY | SIGNAL-TRANSDUCTION | MATRIX METALLOPROTEINASES | invasion | IN-VIVO | motility | FOCAL ADHESION KINASE | GROWTH-FACTOR | V-SRC | Crk-Associated Substrate Protein | Laminin - pharmacology | Oncogene Protein pp60(v-src) - metabolism | Pseudopodia - ultrastructure | rac GTP-Binding Proteins - metabolism | Phosphoproteins - metabolism | Protein-Tyrosine Kinases - deficiency | Focal Adhesion Kinase 1 | Recombinant Fusion Proteins - metabolism | Cell Movement - genetics | Proteins | Matrix Metalloproteinase 9 - metabolism | Protein-Tyrosine Kinases - genetics | Cell Size - genetics | Matrix Metalloproteinase 9 - genetics | rac GTP-Binding Proteins - genetics | JNK Mitogen-Activated Protein Kinases | Collagen - pharmacology | Eukaryotic Cells - enzymology | Fibronectins - pharmacology | Cells, Cultured | Focal Adhesion Protein-Tyrosine Kinases | Genetic Vectors - metabolism | Proteoglycans - metabolism | Oncogene Protein pp60(v-src) - genetics | Signal Transduction - genetics | Phosphoproteins - genetics | Fibronectins - metabolism | Genetic Vectors - genetics | Collagen - metabolism | Neoplasm Metastasis - genetics | Animals | Proteoglycans - pharmacology | Pseudopodia - metabolism | Retinoblastoma-Like Protein p130 | Pseudopodia - genetics | Recombinant Fusion Proteins - genetics | Mitogen-Activated Protein Kinases - genetics | Eukaryotic Cells - cytology | Mice | Laminin - metabolism | Neoplasm Invasiveness - genetics | Drug Combinations | Mitogen-Activated Protein Kinases - metabolism | Tumor antigens | Cytology | Cell adhesion | Physiological aspects | Genetic aspects | Research | Gene expression | Genetic regulation | Cell migration | Cellular biology | Index Medicus | motility; invasion; FAK; Src; JNK
Journal Article
Urology, ISSN 0090-4295, 2015, Volume 86, Issue 6, pp. 1241.e1 - 1241.e9
Objective To determine whether insulin-like growth factor (IGF-1) deficiency can cause testicular damage and to examine changes of the testicular morphology... 
Urology | SYSTEM | LIVER-CIRRHOSIS | HORMONE | LEYDIG-CELLS | HUMAN SKIN | ALCOHOL | HUMAN TESTIS | ATROPHY | UROLOGY & NEPHROLOGY | EXPRESSION | GROWTH-FACTOR-I | Insulin-Like Growth Factor I - pharmacology | Gene Expression - drug effects | Gene Expression - genetics | beta Catenin - analysis | Zonula Occludens-1 Protein - analysis | Male | Insulin-Like Growth Factor I - genetics | Vascular Endothelial Growth Factor A - genetics | Tight Junctions - chemistry | Blood-Testis Barrier - chemistry | Cytochrome P-450 CYP3A - genetics | Fertilins | Disease Models, Animal | Receptors, FSH - analysis | Insulin-Like Growth Factor Binding Proteins - genetics | CD18 Antigens - genetics | Extracellular Matrix Proteins - genetics | Insulin-Like Growth Factor I - deficiency | Metalloproteases - genetics | Organ Size | Cadherins - analysis | Genotype | Signal Transduction - genetics | Receptor, IGF Type 1 - genetics | Receptors, Somatotropin - genetics | Testis - chemistry | Transforming Growth Factor alpha - genetics | Membrane Glycoproteins - genetics | Receptors, Somatotropin - analysis | Tissue Inhibitor of Metalloproteinase-1 - genetics | Animals | Testis - pathology | Transforming Growth Factor beta - genetics | Signal Transduction - drug effects | Connective Tissue Growth Factor - genetics | Inhibins - genetics | Mice | Testis - physiopathology | ADAM Proteins - genetics | Proteoglycans - genetics | Gene expression | Physiological aspects | Somatotropin | Analysis | Genes | Index Medicus
Journal Article
Genome Research, ISSN 1088-9051, 11/2015, Volume 25, Issue 11, pp. 1646 - 1655
Journal Article
PLOS Genetics, ISSN 1553-7390, 2011, Volume 7, Issue 3, pp. e1001324 - e1001324