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The journal of histochemistry and cytochemistry, ISSN 1551-5044, 2016, Volume 46, Issue 1, pp. 19 - 27
Agrin is a heparan sulfate proteoglycan (HSPG) that is highly concentrated in the synaptic basal lamina at the neuromuscular junction (NMJ). Agrin-like... 
Heparitin Sulfate/metabolism | Neuromuscular Junction/metabolism | Proteoglycans/metabolism | Enzyme-Linked Immunosorbent Assay | Heparan Sulfate Proteoglycans/metabolism | Agrin/biosynthesis | Humans | Rats | Muscle, Skeletal/metabolism | Kidney Cortex/cytology | Antibodies, Monoclonal | Bungarotoxins/metabolism | Immune Sera/metabolism | Microscopy, Immunoelectron | Kidney Glomerulus/cytology | Animals | Adult | Basement Membrane/metabolism | Fluorescent Antibody Technique, Indirect | Microscopy, Fluorescence | Glomerular basement membrane | Agrin | Perlecan | Heparan sulfate proteoglycan | ALPHA-DYSTROGLYCAN | HUMAN TISSUES | DOMAIN-III | RAT | RECEPTOR | PROTEINURIA | MONOCLONAL-ANTIBODY | WIDESPREAD EXPRESSION | CELL BIOLOGY | agrin | perlecan | EXTRACELLULAR-MATRIX | glomerular basement membrane | heparan sulfate proteoglycan | BINDING | Basement Membrane - ultrastructure | Kidney Cortex - metabolism | Neuromuscular Junction - metabolism | Muscle, Skeletal - metabolism | Heparitin Sulfate - metabolism | Kidney Glomerulus - ultrastructure | Agrin - biosynthesis | Immune Sera - metabolism | Kidney Glomerulus - metabolism | Bungarotoxins - metabolism | Kidney Glomerulus - cytology | Kidney Cortex - cytology | Proteoglycans - metabolism | Basement Membrane - metabolism | Neuromuscular Junction - ultrastructure | Heparan Sulfate Proteoglycans - metabolism | Agrin - immunology
Journal Article
The Journal of neuroscience, ISSN 1529-2401, 2011, Volume 31, Issue 42, pp. 14899 - 14909
Multiple sclerosis is a demyelinating disease that affects similar to 2,000,000 people worldwide. In the advanced stages of the disease, endogenous... 
OLIGODENDROCYTE PRECURSORS | FIBROBLAST GROWTH FACTOR-2 | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | MEDICAL PROGRESS | DEMYELINATED LESIONS | ENDOTHELIAL-CELLS | MIRROR MOVEMENTS | DOWN-REGULATION | SYNDROME GENE | LINKED KALLMANNS-SYNDROME | NEUROSCIENCES | Oligodendroglia - metabolism | Cricetulus | Humans | Middle Aged | Cerebral Cortex - pathology | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Male | Glial Fibrillary Acidic Protein - metabolism | Phosphoproteins - metabolism | Cerebral Cortex - metabolism | Antigens, CD - metabolism | Oligodendroglia - drug effects | Transfection - methods | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gangliosides - metabolism | Up-Regulation - physiology | Aged, 80 and over | Fibroblast Growth Factor 2 - metabolism | Adult | Female | Membrane Proteins - metabolism | HLA-DR Antigens - metabolism | Extracellular Matrix Proteins - metabolism | Adult Stem Cells - drug effects | Multiple Sclerosis - metabolism | Cricetinae | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Proteoglycans - metabolism | Antigens - metabolism | Multiple Sclerosis - classification | Nerve Tissue Proteins - metabolism | Oligodendroglia - pathology | Up-Regulation - drug effects | Adult Stem Cells - metabolism | Pyrroles - pharmacology | Animals | Zonula Occludens-1 Protein | Antigens, Differentiation, Myelomonocytic - metabolism | Multiple Sclerosis - pathology | Aged | Mice | Postmortem Changes
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 1864 - 11
Central corneal thickness (CCT) is a highly heritable trait associated with complex eye diseases such as keratoconus and glaucoma. We perform a genome-wide... 
DECORIN | CHROMATIN STATES | POLYMORPHISMS | RISK-FACTOR | MULTIDISCIPLINARY SCIENCES | MOUSE | GENE-EXPRESSION | MUTATIONS | HERITABILITY | LUMICAN | KERATOCONUS | Lumican - metabolism | Glaucoma, Open-Angle - genetics | Humans | Corneal Diseases - metabolism | Corneal Dystrophies, Hereditary - ethnology | Corneal Diseases - genetics | Ehlers-Danlos Syndrome - genetics | Corneal Dystrophies, Hereditary - pathology | Loeys-Dietz Syndrome - metabolism | Mendelian Randomization Analysis | Fibrillin-1 - metabolism | Cornea - pathology | Keratoconus - pathology | Corneal Diseases - pathology | Decorin - genetics | Gene Expression | Eye Diseases, Hereditary - pathology | Lumican - genetics | ADAMTS Proteins - metabolism | Proteoglycans - metabolism | Ehlers-Danlos Syndrome - ethnology | European Continental Ancestry Group | Myopia - pathology | Cornea - metabolism | Myopia - ethnology | Loeys-Dietz Syndrome - pathology | Corneal Diseases - ethnology | Marfan Syndrome - metabolism | Marfan Syndrome - pathology | Cornea - abnormalities | Quantitative Trait Loci | Proteoglycans - genetics | ADAMTS Proteins - genetics | Transforming Growth Factor beta2 - metabolism | Corneal Dystrophies, Hereditary - genetics | Glaucoma, Open-Angle - pathology | Keratoconus - metabolism | Loeys-Dietz Syndrome - ethnology | Glaucoma, Open-Angle - ethnology | Myopia - metabolism | Ehlers-Danlos Syndrome - pathology | Marfan Syndrome - ethnology | Keratoconus - genetics | Glaucoma, Open-Angle - metabolism | Fibrillin-1 - genetics | Eye Diseases, Hereditary - ethnology | Genome-Wide Association Study | Quantitative Trait, Heritable | Corneal Dystrophies, Hereditary - metabolism | Marfan Syndrome - genetics | Eye Diseases, Hereditary - genetics | Myopia - genetics | Asian Continental Ancestry Group | Keratoconus - ethnology | Ehlers-Danlos Syndrome - metabolism | Loeys-Dietz Syndrome - genetics | Polymorphism, Single Nucleotide | Transforming Growth Factor beta2 - genetics | Genome, Human | Decorin - metabolism | Eye Diseases, Hereditary - metabolism | Glaucoma | Cornea | Genes | Myopia | Association analysis | Genomes | Gene expression | Tissues | Connective tissues | Keratoconus | Collagen | Eye diseases | Extracellular matrix
Journal Article
Neuron, ISSN 0896-6273, 2003, Volume 40, Issue 3, pp. 485 - 499
The CNS is thought to develop from self-renewing stem cells that generate neurons, astrocytes, and oligodendrocytes. Other data, however, have suggested that... 
OLIGODENDROCYTE LINEAGE | PROGENITOR CELLS | TRANSCRIPTION FACTORS | GLIAL-RESTRICTED PRECURSORS | RAT CEREBRAL-CORTEX | SONIC HEDGEHOG | EMBRYONIC SPINAL-CORD | NEURAL-TUBE | CENTRAL-NERVOUS-SYSTEM | MAMMALIAN FOREBRAIN | NEUROSCIENCES | Immunohistochemistry | Green Fluorescent Proteins | O Antigens - metabolism | Embryo, Mammalian | Cell Count | Homeodomain Proteins - metabolism | Fibroblast Growth Factor 2 - pharmacology | Glial Fibrillary Acidic Protein - metabolism | Hedgehog Proteins | RNA, Messenger - biosynthesis | Time Factors | SOXE Transcription Factors | Neurons - metabolism | Basic Helix-Loop-Helix Transcription Factors | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Enzyme Inhibitors - pharmacology | Proteoglycans - metabolism | Rats | Oligodendrocyte Transcription Factor 2 | Mice | Astrocytes - metabolism | Oligodendroglia - metabolism | Flow Cytometry - methods | Epithelial Cells - metabolism | Epithelial Cells - drug effects | PAX7 Transcription Factor | Carbocyanines - metabolism | DNA-Binding Proteins - metabolism | Dose-Response Relationship, Drug | Tubulin - metabolism | Transfection | Reverse Transcriptase Polymerase Chain Reaction - methods | beta-Galactosidase - metabolism | Fibroblast Growth Factor 2 - physiology | Bromodeoxyuridine - metabolism | Spinal Cord - cytology | Cell Differentiation - physiology | High Mobility Group Proteins - metabolism | Cells, Cultured | Zebrafish Proteins | Antigens - metabolism | Body Patterning - physiology | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Spinal Cord - embryology | Blotting, Northern | Animals | Cell Aggregation | Stem Cells - physiology | Trans-Activators - metabolism | Epidermal Growth Factor - pharmacology | In Vitro Techniques | Luminescent Proteins - metabolism | Spinal cord | Scholarships & fellowships | Neurosciences | Rodents | Stem cells | Experiments | Neurogenesis
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