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Laboratory Investigation, ISSN 0023-6837, 2008, Volume 88, Issue 3, pp. 264 - 274
A fine balance between anabolic and catabolic mechanisms maintains extracellular matrix homeostasis in articular cartilage, and shifts toward degradation are... 
MMP | β-catenin signaling | Articular cartilage | Chondrocyte | Wnt | Osteoarthritis | articular cartilage | ENDOCHONDRAL OSSIFICATION | TRANSCRIPTION FACTORS | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATED PROTEIN-KINASE | osteoarthritis | PATHOLOGY | BETA-CATENIN | beta-catenin signaling | DIFFERENTIATED PHENOTYPE | CARTILAGE | chondrocyte | BONE | EXPRESSION | Immunohistochemistry | Chondrocytes - cytology | Luciferases - metabolism | Extracellular Matrix - metabolism | Cytoplasm - metabolism | L Cells (Cell Line) | Proteoglycans - secretion | Wnt Proteins - metabolism | Hemagglutinins - metabolism | Extracellular Matrix - genetics | Cell Nucleus - metabolism | Transfection | Trypsin - pharmacology | Wnt Proteins - genetics | Cartilage, Articular - metabolism | Interleukin-1beta - metabolism | Adenoviridae - genetics | Female | Cell Culture Techniques | Osteoarthritis - pathology | Chondrocytes - metabolism | Genes, Reporter | Disease Models, Animal | Recombinant Proteins - metabolism | Rabbits | Guinea Pigs | Signal Transduction | beta Catenin | Luciferases - analysis | Matrix Metalloproteinase 13 - genetics | Cells, Cultured | Joints - pathology | Matrix Metalloproteinase 3 - metabolism | Proteoglycans - analysis | Cell Separation - methods | Epitopes | Recombinant Proteins - pharmacology | Matrix Metalloproteinase 13 - metabolism | Culture Media, Conditioned | ADAM Proteins - metabolism | Animals | Mice | Wnt Proteins - physiology | ADAM Proteins - genetics | Cartilage, Articular - drug effects | Matrix Metalloproteinase 3 - genetics | Index Medicus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 4/2003, Volume 161, Issue 1, pp. 169 - 186
Neurogenesis is known to persist in the adult mammalian central nervous system (CNS). The identity of the cells that generate new neurons in the postnatal CNS... 
Adult stem cells | Neurons | Multipotent stem cells | Stem cells | Central nervous system | Fluorescence | Neural stem cells | Progenitor cells | Cells | Hippocampus | Differentiation | Glia | Oligodendrocyte progenitor | Adult neurogenesis | Stem cell | adult neurogenesis | OPTIC-NERVE | differentiation | RADIAL GLIAL-CELLS | OLIGODENDROCYTE PRECURSOR CELLS | MOUSE | glia | CELL BIOLOGY | HIPPOCAMPUS | NEURAL STEM-CELLS | GREEN FLUORESCENT PROTEIN | oligodendrocyte progenitor | stem cell | ADULT-RAT | CENTRAL-NERVOUS-SYSTEM | DENTATE GYRUS | Oligodendroglia - metabolism | Nestin | Action Potentials - genetics | gamma-Aminobutyric Acid - metabolism | Multipotent Stem Cells - metabolism | Neurons - cytology | Spheroids, Cellular - cytology | Promoter Regions, Genetic - genetics | Recombinant Fusion Proteins | Cell Differentiation - genetics | Models, Animal | Neurons - metabolism | Oligodendroglia - cytology | Hippocampus - growth & development | Animals, Newborn | Astrocytes - cytology | 2',3'-Cyclic-Nucleotide Phosphodiesterases - genetics | Dentate Gyrus - metabolism | Neural Pathways - growth & development | Spheroids, Cellular - metabolism | Cells, Cultured | Proteoglycans - metabolism | Mice, Transgenic | Antigens - metabolism | Nerve Tissue Proteins | 2',3'-Cyclic-Nucleotide Phosphodiesterases - metabolism | Hippocampus - cytology | Hippocampus - metabolism | Dentate Gyrus - cytology | Phenotype | Animals | Multipotent Stem Cells - cytology | Neural Pathways - cytology | Dentate Gyrus - growth & development | Neural Pathways - metabolism | Mice | Intermediate Filament Proteins - metabolism | Proteoglycans - genetics | Antigens - genetics | Astrocytes - metabolism | Neurogenetics | Research | Pregnancy | Cellular biology | NG2 antigen | Index Medicus | stem cell; oligodendrocyte progenitor; differentiation; adult neurogenesis; glia
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 05/2008, Volume 215, Issue 2, pp. 452 - 463
Journal Article
Science, ISSN 0036-8075, 4/2011, Volume 332, Issue 6028, pp. 484 - 488
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, pp. e68332 - e68332
Previously, we screened a proteoglycan for anti-hyperglycemic, named FYGL, from Ganoderma Lucidum. For further research of the antidiabetic mechanisms of FYGL... 
INSULIN | CELLS | PROTEIN | MESSENGER-RNA | TYROSINE-PHOSPHATASE 1B | MULTIDISCIPLINARY SCIENCES | LIVER | RESISTANCE | GLUCOKINASE | EXTRACTS | GENE-TRANSCRIPTION | Islets of Langerhans - drug effects | Liver - enzymology | C-Peptide - blood | Antioxidants - metabolism | Glycated Hemoglobin A - metabolism | Male | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Insulin - blood | Liver - drug effects | Islets of Langerhans - metabolism | Muscle, Skeletal - drug effects | C-Peptide - metabolism | Disease Models, Animal | Glucose Transporter Type 4 | Glucose Transporter Type 2 | Liver - metabolism | Mice, Inbred C57BL | Insulin Resistance | Glucokinase - metabolism | Hypolipidemic Agents - pharmacology | Reishi - metabolism | Hypoglycemic Agents - pharmacology | Blood Glucose - drug effects | Diabetes Mellitus, Type 2 - blood | Insulin - metabolism | Animals | Proteoglycans - pharmacology | Phosphoenolpyruvate Carboxykinase (ATP) - metabolism | Glucose - metabolism | Mice | Oxidative Stress - drug effects | Diabetes Mellitus, Type 2 - drug therapy | Biological Factors - pharmacology | Antioxidants | Isoenzymes | Analysis | Anticholesteremic agents | Muscles | Glycosylated hemoglobin | Amino acids | Hypoglycemic agents | Glucose | Dextrose | Oxidative stress | Animal models | Laboratories | Homeostasis | Pyruvic acid | Phosphatase | Fruit bodies | Proteins | Engineering | Signal transduction | Reduction | Hyperglycemia | Chinese medicine | Rodents | Hemoglobin | Protein transport | Pancreas | Polymers | Drug dosages | Glucose transporter | Enzymes | Ganoderma lucidum | Secretion | Complications | Diabetes mellitus | Metabolism | Insulin | Skeletal muscle | Herbal medicine | Glucokinase | Diabetes | Transporter | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 2006, Volume 127, Issue 3, pp. 523 - 537
Journal Article
PLoS Pathogens, ISSN 1553-7366, 04/2012, Volume 8, Issue 4, pp. e1002616 - e1002616
Pseudomonas aeruginosa, an important opportunistic pathogen of man, exploits numerous factors for initial attachment to the host, an event required to... 
ACTIVATED PROTEIN-KINASE | GROWTH-FACTOR-RECEPTOR | MICROBIOLOGY | CELL POLARITY | TRANSMEMBRANE CONDUCTANCE REGULATOR | IN-VITRO | INVASION | VIROLOGY | INNATE IMMUNE-RESPONSES | TRANSACTIVATION | IV PILI | PARASITOLOGY | WOUND REPAIR | Pseudomonas aeruginosa - immunology | Lung - microbiology | Receptor, Epidermal Growth Factor - genetics | Heparin - metabolism | Adhesins, Bacterial - genetics | Humans | Heparin - genetics | Phosphatidylinositol 3-Kinases - metabolism | Fimbriae, Bacterial - genetics | Enzyme Activation - immunology | Phosphatidylinositol 3-Kinases - immunology | Proto-Oncogene Proteins c-akt - genetics | Adhesins, Bacterial - metabolism | Respiratory Mucosa - microbiology | Pseudomonas Infections - metabolism | Receptor, Epidermal Growth Factor - metabolism | Heparan Sulfate Proteoglycans - genetics | Pseudomonas aeruginosa - metabolism | Respiratory Mucosa - immunology | Flagella - immunology | Fimbriae, Bacterial - immunology | Lung - metabolism | Flagella - genetics | Proto-Oncogene Proteins c-akt - metabolism | Cell Line | Receptor, Epidermal Growth Factor - immunology | Bacterial Adhesion - immunology | Pseudomonas Infections - microbiology | Heparan Sulfate Proteoglycans - immunology | Pseudomonas Infections - genetics | Pseudomonas Infections - immunology | Phosphatidylinositol 3-Kinases - genetics | Heparin - immunology | Flagella - metabolism | Proto-Oncogene Proteins c-akt - immunology | Pseudomonas aeruginosa - genetics | Heparan Sulfate Proteoglycans - metabolism | Bacterial Adhesion - genetics | Mutation | Respiratory Mucosa - metabolism | Adhesins, Bacterial - immunology | Enzyme Activation - genetics | Lung - immunology | Fimbriae, Bacterial - metabolism | Epithelial cells | Physiological aspects | Pseudomonas aeruginosa | Research | Virulence (Microbiology) | Health aspects | Airway (Medicine) | Protein binding | Heparan sulfate | Proteins | Epidermal growth factor | Microbiology | Mortality | Infections | Bacteriology | Index Medicus
Journal Article
FEBS Journal, ISSN 1742-464X, 05/2013, Volume 280, Issue 10, pp. 2382 - 2398
During progression to heart failure (HF), myocardial extracellular matrix (ECM) alterations and tissue inflammation are central. Lumican is an ECM‐localized... 
heart failure | lumican | fibrosis | inflammation | pressure overload | LYSYL OXIDASE | DIFFERENTIAL EXPRESSION | RISK-FACTORS | COLLAGEN CROSS-LINKING | BIOCHEMISTRY & MOLECULAR BIOLOGY | METALLOPROTEINASES | IN-VITRO | INHIBITION | LEUCINE-RICH PROTEOGLYCANS | MOUSE MODEL | EXTRACELLULAR-MATRIX | Cardiomyopathy, Dilated - pathology | Interleukin-1beta - pharmacology | Phosphorylation | Chondroitin Sulfate Proteoglycans - genetics | Rats, Wistar | Humans | Middle Aged | Transforming Growth Factor beta1 - metabolism | Extracellular Matrix - metabolism | Stress, Mechanical | Male | NF-kappa B - metabolism | Smad3 Protein - metabolism | RNA, Messenger - metabolism | Smad3 Protein - genetics | Chondroitin Sulfate Proteoglycans - pharmacology | Adult | Female | Keratan Sulfate - pharmacology | Lumican | Lung - metabolism | Fibroblasts - metabolism | Animals, Newborn | Lung - pathology | Collagen Type I - metabolism | Echocardiography | Signal Transduction | Mice, Inbred C57BL | RNA, Messenger - genetics | Chondroitin Sulfate Proteoglycans - metabolism | Keratan Sulfate - metabolism | Organ Size | Rats | Heart Failure - metabolism | Transforming Growth Factor beta1 - genetics | Heart Failure - pathology | Fibroblasts - pathology | Keratan Sulfate - genetics | Cardiomyopathy, Dilated - metabolism | Animals | Mice | Oxidases | Heart failure | Bone morphogenetic proteins | RNA | Collagen | Proteins | Cytokines | Cellular biology | Pathogenesis | Index Medicus
Journal Article
Journal Article