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Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 39, pp. 16211 - 16220
Macroautophagy is a fundamental and evolutionarily conserved catabolic process that eradicates damaged and aging macromolecules and organelles in eukaryotic... 
MATRIX METALLOPROTEINASES | SIGNALING PATHWAYS | LIPID-METABOLISM | ENDOREPELLIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | GROWTH | IMPRINTED GENE | VII COLLAGEN | CANCER | LYSOSOMAL BIOGENESIS | Endothelium, Vascular - cytology | AMP-Activated Protein Kinases - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Endothelium, Vascular - drug effects | Aorta - metabolism | Recombinant Fusion Proteins - metabolism | Autophagy - drug effects | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - agonists | Vascular Endothelial Growth Factor Receptor-2 - genetics | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | RNA Interference | Kruppel-Like Transcription Factors - metabolism | Human Umbilical Vein Endothelial Cells - cytology | Peptide Fragments - genetics | Decorin - genetics | Recombinant Proteins - metabolism | Peptide Fragments - metabolism | Human Umbilical Vein Endothelial Cells - drug effects | AMP-Activated Protein Kinases - antagonists & inhibitors | Aorta - drug effects | Cells, Cultured | Recombinant Proteins - chemistry | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Recombinant Fusion Proteins - chemistry | Kruppel-Like Transcription Factors - chemistry | Gene Expression Regulation - drug effects | Receptors, Growth Factor - agonists | Peptide Fragments - chemistry | Animals | Signal Transduction - drug effects | Endothelium, Vascular - metabolism | Active Transport, Cell Nucleus - drug effects | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Protein Kinase Inhibitors - pharmacology | Aorta - cytology | Kruppel-Like Transcription Factors - genetics | Sus scrofa | Decorin - metabolism | Receptors, Growth Factor - metabolism | Index Medicus | Glycobiology and Extracellular Matrices | autophagy | decorin | endothelial cell | VEGF | proteoglycan
Journal Article
Matrix Biology, ISSN 0945-053X, 05/2012, Volume 31, Issue 4, pp. 234 - 245
Perlecan (Hspg2) is a heparan sulfate proteoglycan expressed in basement membranes and cartilage. Perlecan deficiency (Hspg2 ) in mice and humans causes lethal... 
VEGF signaling | Vascular invasion | Growth plate | Endochondral bone formation | Perlecan | FACTOR-RECEPTOR | SCHWARTZ-JAMPEL-SYNDROME | DYSSEGMENTAL DYSPLASIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | BRANCHING MORPHOGENESIS | SILVERMAN-HANDMAKER TYPE | CARTILAGE DEVELOPMENT | CELL BIOLOGY | IMPAIRED ANGIOGENESIS | HEPARAN-SULFATE | ENDOTHELIAL GROWTH-FACTOR | ALPHA-2-BETA-1 INTEGRIN | Growth Plate - pathology | Cartilage - pathology | Mice, Transgenic - metabolism | Vascular Endothelial Growth Factor A - metabolism | Hypertrophy - metabolism | Embryo, Mammalian - metabolism | Heparan Sulfate Proteoglycans - genetics | Bone Marrow - metabolism | Cell Differentiation | Transgenes | Chondrocytes - metabolism | Chondrocytes - pathology | Signal Transduction | Endothelial Cells - metabolism | Matrix Metalloproteinase 13 - genetics | Mice, Transgenic - genetics | Cartilage - metabolism | Growth Plate - metabolism | Basement Membrane - metabolism | Matrix Metalloproteinase 13 - metabolism | Mice, Knockout | Animals | Embryo, Mammalian - embryology | Heparan Sulfate Proteoglycans - metabolism | Bone Marrow - pathology | Mice | Neovascularization, Pathologic - metabolism | Endothelial Cells - pathology | Osteoblasts - metabolism | Osteogenesis | Cell Movement | Endothelial growth factors | Vascular endothelial growth factor | Cells | Index Medicus
Journal Article
Stem Cells and Development, ISSN 1547-3287, 08/2013, Volume 22, Issue 16, pp. 2298 - 2314
Stem cells ensure tissue regeneration, while overgrowth of adipogenic cells may compromise organ recovery and impair function. In myopathies and muscle atrophy... 
Original Research Reports | PROGENITOR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | BONE-MARROW | BLOOD-VESSEL FORMATION | MICROVASCULAR PERICYTES | MYOGENIC SATELLITE CELLS | MESENCHYMAL STEM-CELLS | PERIVASCULAR CELLS | CELL & TISSUE ENGINEERING | TRANSPLANTATION | SMOOTH-MUSCLE | IN-VIVO | MUSCULAR-DYSTROPHIES | HEMATOLOGY | Pericytes - cytology | Male | Muscle, Skeletal - metabolism | CD146 Antigen - genetics | Green Fluorescent Proteins - genetics | Muscle, Skeletal - injuries | Muscle, Skeletal - cytology | Receptor, Platelet-Derived Growth Factor beta - genetics | Regeneration - genetics | Pericytes - transplantation | Nestin - genetics | Female | Adipogenesis - genetics | Cell Lineage - genetics | Genes, Reporter | Receptor, Platelet-Derived Growth Factor beta - metabolism | Green Fluorescent Proteins - metabolism | Gene Expression | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Pericytes - metabolism | Proteoglycans - metabolism | Mice, Transgenic | Antigens - metabolism | Nestin - metabolism | Animals | CD146 Antigen - metabolism | Endothelial Cells - cytology | Mice, Nude | Receptor, Platelet-Derived Growth Factor alpha - genetics | Luminescent Proteins - genetics | Mice | Proteoglycans - genetics | Antigens - genetics | Luminescent Proteins - metabolism | Muscles | Physiological aspects | Contractility (Biology) | Regeneration | Research | Endothelium | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2013, Volume 288, Issue 4, pp. 2210 - 2222
Journal Article
Journal of cell science, ISSN 0021-9533, 2004, Volume 117, Issue Part 15, pp. 3189 - 3199
Journal Article
Cell, ISSN 0092-8674, 03/2005, Volume 120, Issue 6, pp. 857 - 871
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, pp. e0184028 - e0184028
Journal Article
Experimental Neurology, ISSN 0014-4886, 2006, Volume 198, Issue 2, pp. 275 - 284
Stem cell transplantation was introduced as a mean of cell replacement therapy, but the mechanism by which it confers clinical improvement in experimental... 
Neural stem cells | Multiple sclerosis | Transplantation | Inflammation | Demyelination | STEM-CELLS | neural stem cells | multiple sclerosis | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | SPINAL-CORD | NEUROSCIENCES | CUTTING EDGE | RECOVERY | MULTIPLE-SCLEROSIS | inflammation | demyelination | transplantation | AXONAL-INJURY | CENTRAL-NERVOUS-SYSTEM | GROWTH-FACTOR | T-CELLS | Nestin | O Antigens - metabolism | Fibroblast Growth Factor 2 - pharmacology | Lymphocyte Function-Associated Antigen-1 - metabolism | Phosphopyruvate Hydratase - metabolism | Green Fluorescent Proteins - genetics | Glial Fibrillary Acidic Protein - metabolism | RNA, Messenger - biosynthesis | Encephalomyelitis, Autoimmune, Experimental - chemically induced | Encephalitis - metabolism | Encephalitis - surgery | Reverse Transcriptase Polymerase Chain Reaction - methods | Neurons - physiology | Female | Neural Cell Adhesion Molecule L1 - metabolism | Neurons - drug effects | Disease Models, Animal | Animals, Newborn | Encephalomyelitis, Autoimmune, Experimental - surgery | Green Fluorescent Proteins - metabolism | Myelin Sheath - pathology | Mice, Inbred C57BL | Sialic Acids - metabolism | Encephalitis - pathology | Gene Expression Regulation - physiology | Proteoglycans - metabolism | Mice, Transgenic | Antigens - metabolism | Ki-1 Antigen - metabolism | Gene Expression Regulation - drug effects | Immunohistochemistry - methods | Nerve Tissue Proteins - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Stem Cell Transplantation - methods | Animals | Axons - pathology | Bromodeoxyuridine - pharmacokinetics | Encephalomyelitis, Autoimmune, Experimental - complications | Blotting, Northern - methods | Mice | Epidermal Growth Factor - pharmacology | Intermediate Filament Proteins - metabolism | Amyloid beta-Protein Precursor | Encephalitis - etiology | Encephalomyelitis | Analysis | Stem cells | T cells | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2014, Volume 289, Issue 6, pp. 3262 - 3275
Background: TGF- is a mediator of lung diseases treated with glucocorticoids, but TGF-/glucocorticoid interactions in the lung have not been studied. Results:... 
Transforming Growth Factor Beta (TGFbeta) | DEXAMETHASONE | SMAD Transcription Factor | Glucocorticoids | PULMONARY ARTERIAL-HYPERTENSION | Lung | BONE MORPHOGENETIC PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL PROLIFERATION | MECHANISMS | BALANCE | PHARMACOKINETICS | CORTICOSTEROIDS | Fibroblast | EXPRESSION | GROWTH-FACTOR-BETA-1 | NIH 3T3 Cells | Receptors, Transforming Growth Factor beta - genetics | Humans | Smad3 Protein - metabolism | Lung - cytology | Smad3 Protein - genetics | Smad2 Protein - genetics | Smad1 Protein - genetics | Female | Lung - metabolism | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Endothelial Cells - metabolism | Protein-Serine-Threonine Kinases - genetics | Smad2 Protein - metabolism | Proteoglycans - metabolism | Activin Receptors, Type I - metabolism | Activin Receptors, Type I - genetics | Animals | Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - metabolism | Signal Transduction - drug effects | Endothelial Cells - cytology | Glucocorticoids - pharmacology | Smad1 Protein - metabolism | Signal Transduction - physiology | Fibroblasts - cytology | Mice | Transforming Growth Factor beta - metabolism | Proteoglycans - genetics | Index Medicus | Signal Transduction
Journal Article