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Nature, ISSN 0028-0836, 03/2012, Volume 483, Issue 7391, pp. 570 - 575
Journal Article
Molecular Cell, ISSN 1097-2765, 06/2015, Volume 58, Issue 6, pp. 1028 - 1039
The bromodomain and extraterminal (BET) protein BRD4 is a validated drug target in leukemia, yet its regulatory function in this disease is not well... 
SELECTIVE-INHIBITION | RECRUITMENT | C/EBP-ALPHA | CREB-BINDING PROTEIN | CHROMATIN | ACETYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | C-MYC | P-TEFB | BRD4 | CELL BIOLOGY | Transcriptional Regulator ERG | NIH 3T3 Cells | Oncogene Proteins - genetics | Humans | Leukemia, Myeloid - genetics | Proto-Oncogene Proteins c-myb - genetics | Gene Expression Profiling | Leukemia, Myeloid - pathology | RNA Interference | Proto-Oncogene Protein c-fli-1 - metabolism | Protein Binding - drug effects | Trans-Activators - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins - metabolism | Acute Disease | Proto-Oncogene Protein c-fli-1 - genetics | CCAAT-Enhancer-Binding Protein-beta - genetics | Oncogene Proteins - metabolism | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | CCAAT-Enhancer-Binding Protein-beta - metabolism | Proto-Oncogene Proteins c-myb - metabolism | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Acetylation - drug effects | Animals | Hematopoietic System - metabolism | Leukemia, Myeloid - metabolism | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Trans-Activators - metabolism | Mice | Histones - metabolism | DNA binding proteins | Medicine, Experimental | Medical research | Chromatin | Lysine
Journal Article
Nature Communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, p. 11208
Journal Article
Nature Medicine, ISSN 1078-8956, 03/2017, Volume 23, Issue 3, pp. 386 - 395
Journal Article
Oncogene, ISSN 0950-9232, 2013, Volume 32, Issue 42, pp. 5089 - 5100
Ewing sarcoma provides an important model for transcription-factor-mediated oncogenic transformation because of its reliance on the ETS-type fusion oncoprotein... 
Ewing sarcoma | Repression | Transcription | NuRD | EWS/FLI | PROTEIN-PROTEIN | TARGET | TRANSFORMATION | CELLS | DNA-BINDING | transcription | BIOCHEMISTRY & MOLECULAR BIOLOGY | PEDIATRIC SOLID TUMORS | FUSION GENE | CELL BIOLOGY | ONCOLOGY | RESPONSE ELEMENTS | GENETICS & HEREDITY | repression | EXPRESSION | REVEALS | Oncogene Proteins, Fusion - metabolism | Humans | Gene Expression Regulation, Neoplastic | Sarcoma, Ewing - pathology | Co-Repressor Proteins - metabolism | Mi-2 Nucleosome Remodeling and Deacetylase Complex - genetics | Mi-2 Nucleosome Remodeling and Deacetylase Complex - metabolism | Bone Neoplasms - pathology | Histone Demethylases - genetics | Cell Transformation, Neoplastic - genetics | Proto-Oncogene Protein c-fli-1 - metabolism | Transcription, Genetic | Bone Neoplasms - genetics | Genes, Tumor Suppressor | Protein Structure, Tertiary | Proto-Oncogene Protein c-fli-1 - genetics | RNA-Binding Protein EWS - genetics | Histone Deacetylases - metabolism | RNA-Binding Protein EWS - metabolism | Co-Repressor Proteins - genetics | Xenograft Model Antitumor Assays | Histone Demethylases - metabolism | Animals | Mice, Nude | Oncogene Proteins, Fusion - genetics | Protein-Lysine 6-Oxidase - metabolism | Cell Line, Tumor | Protein-Lysine 6-Oxidase - genetics | Sarcoma, Ewing - genetics | Genetic aspects | Genetic transcription | Research | Carcinogenesis | Ewing's sarcoma | Testing | Cancer | Proteins | Cellular biology | Gene expression | EWS | FLI
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2015, Volume 47, Issue 9, pp. 1073 - 1078
Journal Article