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Nature, ISSN 0028-0836, 12/2010, Volume 468, Issue 7326, pp. 973 - 977
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2009, Volume 106, Issue 48, pp. 20411 - 20416
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2008, Volume 105, Issue 8, pp. 3041 - 3046
Journal Article
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, pp. 6744 - 6744
Pancreatic ductal adenocarcinoma (PDA) has a dismal prognosis and insights into both disease etiology and targeted intervention are needed. A total of 109... 
SIGNATURES | MODELS | DUCTAL ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | TUMOR | SOMATIC MUTATION | COPY-NUMBER ALTERATION | GENOMIC CHARACTERIZATION | CARCINOMA | PROGRESSION | DISCOVERY | Cell Cycle - genetics | RNA-Binding Proteins - genetics | Prognosis | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Middle Aged | Carcinoma, Adenosquamous - drug therapy | Male | Antineoplastic Agents - therapeutic use | DNA Repair - genetics | Molecular Targeted Therapy | Tumor Suppressor Protein p53 - genetics | Carcinoma, Pancreatic Ductal - genetics | DNA Copy Number Variations | Genetic Variation | Pancreatic Neoplasms - drug therapy | Aged, 80 and over | Adult | Female | Nuclear Proteins - genetics | Carcinoma, Adenosquamous - pathology | Pancreatic Neoplasms - pathology | Kaplan-Meier Estimate | Pancreatic Neoplasms - genetics | Carcinoma, Adenosquamous - genetics | Transcription Factors - genetics | Carcinoma, Pancreatic Ductal - pathology | Sequence Analysis, DNA | Carcinoma, Pancreatic Ductal - drug therapy | Drug Resistance, Neoplasm - genetics | Exome - genetics | Gene Amplification | Sulfonamides - therapeutic use | Wnt Signaling Pathway - genetics | Proto-Oncogene Proteins B-raf - genetics | Retinoblastoma Protein - genetics | Genes, myc - genetics | Indoles - therapeutic use | Aged | BRCA2 Protein - genetics | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7339, pp. 467 - 472
Multiple myeloma is an incurable malignancy of plasma cells, and its pathogenesis is poorly understood. Here we report the massively parallel sequencing of 38... 
PATHOGENESIS | B-CELL LYMPHOMA | BLIMP-1 | GENE | MULTIDISCIPLINARY SCIENCES | STRESS-RESPONSE | EXOSOME | CLASSIFICATION | DIFFERENTIATION | HUMAN CANCER | SOMATIC MUTATIONS | Ribonucleases - genetics | Ribonucleases - chemistry | Genomics | Humans | Molecular Sequence Data | NF-kappa B - metabolism | DNA Repair - genetics | Multiple Myeloma - drug therapy | DNA Mutational Analysis | Protein Biosynthesis - genetics | Multiple Myeloma - enzymology | Proto-Oncogene Proteins B-raf - metabolism | Amino Acid Sequence | Oncogenes - genetics | Models, Molecular | Exons - genetics | Signal Transduction - genetics | Multiple Myeloma - metabolism | Mutation - genetics | Open Reading Frames - genetics | Genome, Human - genetics | Homeodomain Proteins - genetics | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | RNA Processing, Post-Transcriptional - genetics | Proto-Oncogene Proteins B-raf - genetics | CpG Islands - genetics | Blood Coagulation - genetics | Protein Conformation | Histones - metabolism | Transcription, Genetic - genetics | Exosome Multienzyme Ribonuclease Complex | Methylation | Homeostasis - genetics | Multiple Myeloma - genetics | Usage | Multiple myeloma | Development and progression | Genetic aspects | Research | Nucleotide sequencing | Methods | Cancer | Proteins | Pathogenesis | Homeostasis | Genetics | Genomes | Mutation | Kinases | Mass spectrometry | Index Medicus
Journal Article
Nature medicine, ISSN 1078-8956, 2015, Volume 21, Issue 11, pp. 1350 - 1356
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 5, pp. 652 - 663
We have investigated the role of individual members of the Raf/Mek/Erk cascade in the onset of oncogene-driven non-small cell lung carcinoma (NSCLC). Ablation... 
C-RAF-1 GENE | APOPTOSIS | TUMOR PROGRESSION | ONCOLOGY | MAP KINASE | GROWTH | ORAL MEK INHIBITOR | PHASE-II | MICE | BRAF | CANCER | CELL BIOLOGY | Fibroblasts - enzymology | Cell Proliferation | Humans | Gene Expression Regulation, Neoplastic | Mitogen-Activated Protein Kinase 1 - deficiency | Lung Neoplasms - pathology | MAP Kinase Kinase 1 - genetics | Transfection | RNA Interference | Time Factors | Cellular Senescence | Mitogen-Activated Protein Kinase 1 - genetics | MAP Kinase Kinase 2 - genetics | Proto-Oncogene Proteins B-raf - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Proto-Oncogene Proteins B-raf - deficiency | Lung Neoplasms - enzymology | MAP Kinase Kinase 2 - deficiency | Mitogen-Activated Protein Kinase 3 - genetics | Proto-Oncogene Proteins c-raf - genetics | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Tumor Burden | Proto-Oncogene Proteins c-raf - metabolism | Mice, Knockout | Gene Expression Regulation, Enzymologic | Animals | Proto-Oncogene Proteins B-raf - genetics | Proto-Oncogene Proteins c-raf - deficiency | Cell Line, Tumor | Mice | Mitogen-Activated Protein Kinase 3 - deficiency | Carcinoma, Non-Small-Cell Lung - enzymology | Genes, ras | Apoptosis | MAP Kinase Kinase 1 - deficiency | Development and progression | Carcinoma | Lung cancer, Non-small cell | Phosphotransferases | Cancer | Index Medicus
Journal Article