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Journal of Clinical Oncology, ISSN 0732-183X, 11/2006, Volume 24, Issue 31, pp. 5034 - 5042
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 06/2009, Volume 27, Issue 16, pp. 2622 - 2629
Purpose PTEN, AKT, and KRAS are epidermal growth factor receptor (EGFR) downstream regulators. KRAS mutations confer resistance to cetuximab. This... 
CELL LUNG-CANCER | PANITUMUMAB | K-RAS MUTATIONS | THERAPY | GROWTH-FACTOR-RECEPTOR | EFFICACY | ONCOLOGY | SIGNALING PATHWAY | RESISTANCE | EGFR | CHEMOTHERAPY | Immunohistochemistry | Predictive Value of Tests | ras Proteins - genetics | Phosphorylation | Proto-Oncogene Proteins p21(ras) | Colorectal Neoplasms - genetics | Humans | Middle Aged | PTEN Phosphohydrolase - analysis | Drug Resistance, Neoplasm | Male | Patient Selection | Antibodies, Monoclonal, Humanized | Antineoplastic Agents, Phytogenic - administration & dosage | Time Factors | DNA Mutational Analysis | Colorectal Neoplasms - drug therapy | Adult | Camptothecin - administration & dosage | Female | Retrospective Studies | Cetuximab | Camptothecin - analogs & derivatives | Colorectal Neoplasms - mortality | Colorectal Neoplasms - enzymology | Risk Assessment | Kaplan-Meier Estimate | Proportional Hazards Models | Proto-Oncogene Proteins - genetics | Treatment Outcome | Receptor, Epidermal Growth Factor - analysis | Protein Kinase Inhibitors - administration & dosage | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins c-akt - analysis | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Colorectal Neoplasms - secondary | Italy - epidemiology | Aged | Mutation | Longitudinal Studies | Index Medicus
Journal Article
Modern Pathology, ISSN 0893-3952, 11/2013, Volume 26, Issue 11, pp. 1525 - 1535
The switch/sucrose non-fermentable (SWI/SNF) subunit ARID1A (AT-rich interactive domain 1A gene) has been recently postulated as a novel tumor suppressor of... 
endometrial cancer | microsatellite instability | ARID1A | Lynch syndrome | METHYLATION | COMPLEX | MSI | REMODELING GENE ARID1A | PATHOLOGY | HNPCC | TUMOR-SUPPRESSOR | GRADE | COMPONENT | MUTATIONS | Immunohistochemistry | MutL Protein Homolog 1 | ras Proteins - genetics | Microsatellite Instability | Proto-Oncogene Proteins p21(ras) | Nuclear Proteins - analysis | Prognosis | Humans | Middle Aged | PTEN Phosphohydrolase - analysis | Gene Expression Regulation, Neoplastic | DNA-Binding Proteins - analysis | SMARCB1 Protein | Tumor Suppressor Protein p53 - analysis | Endometrial Neoplasms - genetics | DNA Mutational Analysis | Aged, 80 and over | Adult | Colorectal Neoplasms, Hereditary Nonpolyposis - enzymology | Female | Nuclear Proteins - genetics | Promoter Regions, Genetic | Genetic Predisposition to Disease | Endometrial Neoplasms - enzymology | Signal Transduction | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Down-Regulation | Gene Silencing | Proto-Oncogene Proteins - genetics | Phosphatidylinositol 3-Kinases - genetics | Phenotype | Class I Phosphatidylinositol 3-Kinases | Chromosomal Proteins, Non-Histone - analysis | Adaptor Proteins, Signal Transducing - genetics | Proto-Oncogene Proteins c-akt - analysis | Endometrial Neoplasms - pathology | Aged | Transcription Factors - analysis | Mutation | Index Medicus
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 01/2011, Volume 88, Issue 1, pp. 42 - 56
Journal Article
Oncogene, ISSN 0950-9232, 01/2011, Volume 30, Issue 2, pp. 142 - 152
Recently, the orphan receptor G protein-coupled receptor 55 (GPR55) has been proposed as a potential cannabinoid receptor, although controversy remains on its... 
prostate cancer | ABC transporters | phospholipase A2 | lysophosphatidylinositol | G-protein-coupled receptor | GPR55 | MIGRATION | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG-RESISTANCE | IDENTIFICATION | CELL BIOLOGY | HUMAN PROSTATE-CANCER | L-ALPHA-LYSOPHOSPHATIDYLINOSITOL | ONCOLOGY | PROTEIN-COUPLED RECEPTOR | LYSOPHOSPHOLIPIDS | GENETICS & HEREDITY | EXPRESSION | Lysophospholipids - metabolism | Prostatic Neoplasms - metabolism | RNA, Small Interfering - genetics | Cell Proliferation | Phospholipases A2 - analysis | Receptors, G-Protein-Coupled - metabolism | Humans | Ovarian Neoplasms - pathology | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Piperidines - pharmacology | Biomarkers, Tumor - metabolism | Female | Ovarian Neoplasms - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Ovarian Neoplasms - drug therapy | Prostatic Neoplasms - drug therapy | Pyrazoles - pharmacology | Autocrine Communication | Prostatic Neoplasms - pathology | Multidrug Resistance-Associated Proteins - analysis | Receptors, G-Protein-Coupled - analysis | Biomarkers, Tumor - analysis | Phospholipases A2 - metabolism | Down-Regulation - drug effects | Extracellular Signal-Regulated MAP Kinases - analysis | Proto-Oncogene Proteins c-akt - analysis | Cell Line, Tumor | Biomarkers, Tumor - genetics | Receptors, G-Protein-Coupled - genetics | Multidrug Resistance-Associated Proteins - metabolism | Cell proliferation | Physiological aspects | Cell receptors | Research | Cancer cells | Proteins | Ribonucleic acid--RNA | Neurons | Cells | Cancer | Index Medicus
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 12/2010, Volume 299, Issue 6, pp. C1562 - C1570
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 09/2007, Volume 13, Issue 17, pp. 4964 - 4973
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0133699 - e0133699
Avian reovirus (ARV) protein p17 has been shown to regulate cell cycle and autophagy by activation of p53/PTEN pathway; nevertheless, it is still unclear how... 
CELL-CYCLE REGULATION | PHOSPHATIDYLINOSITOL 3-KINASE/AKT | APOPTOSIS | PORE COMPLEX | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | KINASE | TRANSCRIPTION | GROWTH | TUMOR-SUPPRESSOR | AKT | TOR Serine-Threonine Kinases - metabolism | Humans | Cercopithecus aethiops | Phosphatidylinositol 3-Kinases - metabolism | Viral Proteins - metabolism | MAP Kinase Signaling System | Protein Interaction Maps | Tumor Suppressor Protein p53 - analysis | Phosphatidylinositol 3-Kinases - analysis | Reoviridae Infections - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Vero Cells | Viral Proteins - analysis | Reoviridae Infections - pathology | Amino Acid Sequence | Cell Line | Signal Transduction | Nuclear Pore Complex Proteins - metabolism | Tumor Suppressor Protein p53 - metabolism | PTEN Phosphohydrolase - metabolism | Nuclear Pore Complex Proteins - analysis | Nuclear Localization Signals | Orthoreovirus, Avian - physiology | Host-Pathogen Interactions | Animals | Proto-Oncogene Proteins c-akt - analysis | Physiological aspects | Cellular signal transduction | Research | Tumor proteins | Reoviruses | Health aspects | Porins | TOR protein | Phosphorylation | Transcription factors | Senescence | Transcription | Agricultural biotechnology | p53 Protein | Viruses | AKT protein | Arrestin | Genomes | Infections | Activation | Kinases | Cyclin D1 | Inactivation | Phosphatase | Autophagy | Nuclei | Accumulation | Cyclin-dependent kinase 4 | Proteins | Signal transduction | Hepatitis | Animal vaccines | Pathways | Cell cycle | Localization | Ubiquitin-protein ligase | Translocation | Deactivation | Extracellular signal-regulated kinase | 1-Phosphatidylinositol 3-kinase | Signaling | Cyclin-dependent kinase inhibitor p21 | Molecular biology | Phagocytosis | Cytoplasm | PTEN protein | Viral infections | Apoptosis | Index Medicus
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 09/2010, Volume 28, Issue 27, pp. 4240 - 4246
Journal Article