X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (23701) 23701
Publication (3983) 3983
Book Review (987) 987
Book Chapter (44) 44
Dissertation (23) 23
Conference Proceeding (22) 22
Data Set (5) 5
Magazine Article (5) 5
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (22765) 22765
proto-oncogene proteins c-akt - metabolism (17617) 17617
humans (16310) 16310
animals (14365) 14365
mice (9152) 9152
phosphorylation (8155) 8155
signal transduction (8108) 8108
phosphatidylinositol 3-kinases - metabolism (6938) 6938
cell line, tumor (6595) 6595
apoptosis (6011) 6011
male (6005) 6005
cell biology (5923) 5923
proto-oncogene proteins c-akt - genetics (5800) 5800
female (5659) 5659
oncology (5461) 5461
signal transduction - drug effects (4917) 4917
biochemistry & molecular biology (4913) 4913
activation (4725) 4725
expression (4716) 4716
akt (4523) 4523
cancer (3901) 3901
proteins (3426) 3426
rats (3320) 3320
proto-oncogene proteins c-akt (3268) 3268
apoptosis - drug effects (3257) 3257
cells, cultured (3225) 3225
kinases (3169) 3169
cell proliferation (3104) 3104
akt protein (2838) 2838
cell line (2803) 2803
gene expression (2755) 2755
proto-oncogene proteins - metabolism (2618) 2618
research (2539) 2539
cell proliferation - drug effects (2508) 2508
phosphorylation - drug effects (2374) 2374
article (2355) 2355
growth (2158) 2158
pathway (2152) 2152
phosphatidylinositol 3-kinases - genetics (2114) 2114
proto-oncogene proteins c-akt - antagonists & inhibitors (2095) 2095
blotting, western (2082) 2082
research article (2078) 2078
signal transduction - physiology (2066) 2066
mice, inbred c57bl (2003) 2003
cells (2002) 2002
analysis (1970) 1970
tor serine-threonine kinases - metabolism (1970) 1970
transfection (1954) 1954
inhibition (1933) 1933
multidisciplinary sciences (1927) 1927
gene expression regulation, neoplastic (1894) 1894
mutation (1884) 1884
protein-serine-threonine kinases - metabolism (1882) 1882
enzyme activation (1849) 1849
mice, knockout (1807) 1807
rna interference (1790) 1790
medicine (1783) 1783
phosphatidylinositol 3-kinases - antagonists & inhibitors (1777) 1777
genetic aspects (1764) 1764
proliferation (1749) 1749
rodents (1744) 1744
physiological aspects (1705) 1705
middle aged (1692) 1692
survival (1642) 1642
cell survival - drug effects (1587) 1587
antineoplastic agents - pharmacology (1585) 1585
extracellular signal-regulated map kinases - metabolism (1565) 1565
down-regulation (1564) 1564
protein-serine-threonine kinases (1552) 1552
metastasis (1544) 1544
health aspects (1522) 1522
science (1495) 1495
tumors (1495) 1495
rna, messenger - metabolism (1492) 1492
up-regulation (1485) 1485
insulin (1473) 1473
gene-expression (1465) 1465
disease models, animal (1446) 1446
phosphatidylinositol 3-kinase (1423) 1423
oxidative stress (1422) 1422
physiology (1409) 1409
cell cycle (1380) 1380
rna, messenger - genetics (1373) 1373
biology (1371) 1371
mice, nude (1366) 1366
in-vivo (1335) 1335
1-phosphatidylinositol 3-kinase (1322) 1322
adult (1319) 1319
time factors (1305) 1305
protein kinase inhibitors - pharmacology (1301) 1301
enzyme inhibitors - pharmacology (1287) 1287
in-vitro (1280) 1280
signal transduction - genetics (1276) 1276
cell growth (1264) 1264
cell survival (1247) 1247
nf-kappa-b (1235) 1235
nf-kappa b - metabolism (1229) 1229
signaling pathway (1228) 1228
breast cancer (1222) 1222
abridged index medicus (1214) 1214
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (23500) 23500
Chinese (153) 153
Japanese (19) 19
Russian (15) 15
French (12) 12
German (3) 3
Spanish (2) 2
Italian (1) 1
Korean (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Blood, ISSN 0006-4971, 11/2014, Volume 124, Issue 19, pp. 3016 - 3019
Journal Article
Cancer Cell, ISSN 1535-6108, 2006, Volume 10, Issue 1, pp. 51 - 64
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2012, Volume 44, Issue 8, pp. 941 - 945
Journal Article
Nature Genetics, ISSN 1061-4036, 08/2012, Volume 44, Issue 8, pp. 934 - 940
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2011, Volume 365, Issue 7, pp. 611 - 619
Journal Article
Journal Article
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2012, Volume 15, Issue 5, pp. 725 - 738
Mammalian target of rapamycin complex 2 (mTORC2) phosphorylates and activates AGC kinase family members, including Akt, SGK1, and PKC, in response to... 
TRANSCRIPTION FACTORS | LIPID-METABOLISM | INSULIN-RESISTANCE | ELEMENT-BINDING PROTEIN-1C | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | MOTIF PHOSPHORYLATION | DIABETIC-NEPHROPATHY | GLUCOSE-UTILIZATION | CELL-GROWTH | PHOSPHOINOSITIDE 3-KINASE | CELL BIOLOGY | Glucose Intolerance - metabolism | Phosphorylation | Liver - enzymology | TOR Serine-Threonine Kinases - metabolism | Homeostasis | Glycogen Synthase Kinase 3 beta | Male | Hepatocytes - metabolism | Mechanistic Target of Rapamycin Complex 2 | Hyperglycemia - genetics | Proto-Oncogene Proteins c-akt - genetics | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - metabolism | Forkhead Transcription Factors - metabolism | Trans-Activators - genetics | Hyperinsulinism - genetics | Insulin - genetics | Lipogenesis | Proto-Oncogene Proteins c-akt - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Gluconeogenesis | Hyperinsulinism - metabolism | Glucose Intolerance - genetics | Signal Transduction | Liver - metabolism | Glucokinase - genetics | Glucose - genetics | Lipid Metabolism | Forkhead Transcription Factors - genetics | Glucokinase - metabolism | Glycogen Synthase Kinase 3 - metabolism | Mice, Knockout | Hyperglycemia - metabolism | Proteins - genetics | Insulin - metabolism | Animals | Proteins - metabolism | Trans-Activators - deficiency | Glycogen Synthase Kinase 3 - genetics | Sterol Regulatory Element Binding Protein 1 - genetics | Glucose - metabolism | Glycolysis | Trans-Activators - metabolism | Forkhead Box Protein O1 | Mice | Transcription Factors | Glucose metabolism | Hyperglycemia | Glucose | Isoenzymes | Dextrose | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2012, Volume 18, Issue 8, pp. 2316 - 2325
Purpose: This study evaluated the clinical relevance of the dual-targeting strategy involving PI3K/AKT/mTOR and RAF/MEK/ERK pathways. Experimental Design: We... 
COLON-CANCER | METASTATIC MELANOMA | PIK3CA MUTATIONS | PI3K | ONCOLOGY | COLORECTAL-CANCER | RESISTANCE | BRAF | ANTITUMOR-ACTIVITY | MEK INHIBITORS | TUMORS | Neoplasms - metabolism | Extracellular Signal-Regulated MAP Kinases - drug effects | TOR Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Middle Aged | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Male | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Molecular Targeted Therapy | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - genetics | Proto-Oncogene Proteins c-akt - genetics | TOR Serine-Threonine Kinases - antagonists & inhibitors | Young Adult | MAP Kinase Signaling System - genetics | TOR Serine-Threonine Kinases - genetics | Neoplasms - genetics | Aged, 80 and over | Adult | Female | Proto-Oncogene Proteins c-akt - metabolism | Proto-Oncogene Proteins p21(ras) - metabolism | Neoplasms - drug therapy | Phosphatidylinositol 3-Kinases - genetics | MAP Kinase Signaling System - drug effects | Proto-Oncogene Proteins B-raf - genetics | Proto-Oncogene Proteins p21(ras) - antagonists & inhibitors | Adolescent | Aged | Mutation | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Index Medicus
Journal Article
Tumor Biology, ISSN 1010-4283, 03/2015, Volume 36, Issue 3, pp. 1477 - 1486
Journal Article