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Journal of Biological Chemistry, ISSN 0021-9258, 1761, Volume 289, Issue 18, pp. 12467 - 12484
Background: Metabolic stresses, including hyperinsulinemia, promote insulin resistance. Results: Monoclonal antibodies raised against Ser(P)/Thr(P) residues in... 
PROTEIN-KINASE-C | SIGNALING PATHWAYS | Metabolic Stress | Signal Transduction | IRS1 | PLECKSTRIN-HOMOLOGY-DOMAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | Insulin Resistance | Insulin Signaling | PHOSPHOPROTEOME REVEALS | Monoclonal Antibodies | Protein Phosphorylation | DIET-INDUCED OBESITY | MASS-SPECTROMETRY | IRS-1 SERINE PHOSPHORYLATION | SKELETAL-MUSCLE CELLS | IN-VIVO | Cell Signaling | Phosphotyrosine Signaling | REGULATORY ROLE | CHO Cells | Cricetulus | TOR Serine-Threonine Kinases - metabolism | Humans | Phosphatidylinositol 3-Kinases - metabolism | Insulin Receptor Substrate Proteins - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Threonine - metabolism | Antigens, CD - genetics | Antigens, CD - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Receptor, Insulin - genetics | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Phosphorylation - drug effects | Insulin Receptor Substrate Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Protein-Serine-Threonine Kinases - metabolism | Insulin - pharmacology | Cricetinae | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Rats | Serine - metabolism | Blotting, Western | Hypoglycemic Agents - pharmacology | Tyrosine - metabolism | Animals | Signal Transduction - drug effects | Tunicamycin - pharmacology | Thapsigargin - pharmacology | Anisomycin - pharmacology | Receptor, Insulin - metabolism | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Index Medicus | Metabolism
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1768, Volume 289, Issue 19, pp. 12989 - 12999
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 1768, Volume 289, Issue 19, pp. 13476 - 13491
Journal Article
The Journal of Physiology, ISSN 0022-3751, 11/2008, Volume 586, Issue 22, pp. 5589 - 5600
Sepsis causes muscle atrophy and insulin resistance, but the underlying mechanisms are unclear. Therefore, the present study examined the effects of... 
KINASE-ACTIVITY | PHYSIOLOGY | ATROPHY | INSULIN-RESISTANCE | LIPOPOLYSACCHARIDE INFUSION | GENE-EXPRESSION | FOXO TRANSCRIPTION FACTORS | ACTIVATION CAUSES | CRITICALLY-ILL PATIENTS | NEUROSCIENCES | PYRUVATE-DEHYDROGENASE COMPLEX | UBIQUITIN-PROTEASOME PATHWAY | SKP Cullin F-Box Protein Ligases - genetics | Male | Muscle, Skeletal - metabolism | Sepsis - complications | RNA, Messenger - metabolism | Proto-Oncogene Proteins c-akt - genetics | Forkhead Transcription Factors - metabolism | Insulin Resistance - physiology | Sepsis - metabolism | Muscle Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Muscular Atrophy - etiology | Protein-Serine-Threonine Kinases - metabolism | Muscular Atrophy - metabolism | Oxidation-Reduction | Signal Transduction | RNA, Messenger - genetics | Carbohydrate Metabolism | Protein-Serine-Threonine Kinases - genetics | Rats | Muscular Atrophy - genetics | SKP Cullin F-Box Protein Ligases - metabolism | Forkhead Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Rats, Sprague-Dawley | Sepsis - genetics | Muscle Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Models, Biological | Insulin Resistance - genetics | Forkhead Box Protein O3 | Lactates | Messenger RNA | Glycogen | Proteolysis | Oxidation-reduction reaction | Insulin resistance | Protein biosynthesis | Mitogens | Index Medicus | Integrative
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2012, Volume 104, Issue 3, pp. 228 - 239
Journal Article
Experimental Neurology, ISSN 0014-4886, 2009, Volume 219, Issue 1, pp. 93 - 103
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 1991, Volume 2, Issue 12, pp. 1001 - 1009
Journal Article
Journal Article
International Journal of Oncology, ISSN 1019-6439, 2008, Volume 33, Issue 5, pp. 959 - 967
Estrogen and progestin are involved in ovarian carcinogenesis. Change in nm23-H1 expression and the PIK3/AKT pathway are involved in carcinogenesis,... 
nm23-H1 | Phosphatidylinositol 3-kinase pathway | Progestin | Estrogen | Ovarian cancer | MIGRATION | estrogen | phosphatidylinositol 3-kinase pathway | progestin | NM23 | ovarian cancer | PHOSPHORYLATION | INDUCTION | ONCOLOGY | SQUAMOUS-CELL CARCINOMA | ENDOMETRIAL | PROGNOSTIC-SIGNIFICANCE | GROWTH-FACTOR | EXPRESSION | ORAL-CONTRACEPTIVES | Phosphorylation | Adenocarcinoma - pathology | Prognosis | Humans | Middle Aged | Ovarian Neoplasms - pathology | Medroxyprogesterone Acetate - pharmacology | Phosphatidylinositol 3-Kinases - metabolism | Ovarian Neoplasms - mortality | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | NM23 Nucleoside Diphosphate Kinases - metabolism | Proto-Oncogene Proteins c-akt - genetics | Cystadenoma, Serous - enzymology | Dose-Response Relationship, Drug | Neoplasm Metastasis | RNA Interference | Time Factors | Female | Estrogens - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cystadenoma, Serous - therapy | Antineoplastic Agents, Hormonal - pharmacology | Adenocarcinoma - enzymology | Progestins - pharmacology | Ovarian Neoplasms - enzymology | Cystadenoma, Serous - mortality | Adenocarcinoma - therapy | Signal Transduction - drug effects | Cell Line, Tumor | Ovarian Neoplasms - therapy | Protein Kinase Inhibitors - pharmacology | Neoplasm Staging | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Adenocarcinoma - mortality | Cell Movement | Cystadenoma, Serous - pathology | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Journal Article