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2010, Advances in experimental medicine and biology, ISBN 1441967052, Volume 687., xvii, 145
This book highlights the relevance of the BCL‑2 family of proteins in apoptosis, physiology and disease... 
pathology | physiology | metabolism | Proto-Oncogene Proteins c-bcl-2 | Tumor proteins | Neoplasms | Apoptosis
Book
Cancer cell, ISSN 1535-6108, 11/2006, Volume 10, Issue 5, pp. 375 - 388
BCL-2 proteins are critical for cell survival and are overexpressed in many tumors... 
CELLCYCLE | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | bcl-2-Associated X Protein - chemistry | Humans | Leukemia, Myeloid, Acute - metabolism | Nitrophenols - metabolism | bcl-2 Homologous Antagonist-Killer Protein - genetics | Piperazines - metabolism | Neoplasm Proteins - metabolism | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Biphenyl Compounds - metabolism | Biphenyl Compounds - therapeutic use | Recombinant Fusion Proteins - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Nitrophenols - therapeutic use | Hematopoietic Stem Cells - physiology | Leukemia, Myeloid, Acute - drug therapy | Proto-Oncogene Proteins c-bcl-2 - chemistry | Dimerization | bcl-2-Associated X Protein - genetics | Protein Structure, Tertiary | Cell Line | bcl-2-Associated X Protein - metabolism | Piperazines - therapeutic use | Animals | Sulfonamides - therapeutic use | Myeloid Cell Leukemia Sequence 1 Protein | Sulfonamides - metabolism | Recombinant Fusion Proteins - genetics | Protein Conformation | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Mice | Apoptosis - physiology | Drug Resistance, Neoplasm - physiology | Proto-Oncogene Proteins c-bcl-2 - genetics | RNA, Small Interfering - metabolism | Proteins | Oncology, Experimental | Lung cancer | Bone marrow | Transplantation | Lymphomas | Research | Hematopoietic stem cells | Cancer | Apoptosis | Index Medicus
Journal Article
Journal Article
Molecular cell, ISSN 1097-2765, 02/2005, Volume 17, Issue 3, pp. 393 - 403
Apoptosis is initiated when Bcl-2 and its prosurvival relatives are engaged by proapoptotic BH3-only proteins via interaction of its BH3 domain with a groove on the Bcl-2-like proteins... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Humans | Molecular Sequence Data | Proto-Oncogene Proteins - chemistry | Neoplasm Proteins - metabolism | Genetic Complementation Test | Proto-Oncogene Proteins c-bcl-2 - metabolism | Bcl-2-Like Protein 11 | Carrier Proteins - chemistry | Proto-Oncogene Proteins c-bcl-2 - chemistry | Membrane Proteins - metabolism | Neoplasm Proteins - genetics | Peptide Fragments - genetics | Cell Survival - physiology | Binding, Competitive | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | bcl-X Protein | Peptide Fragments - metabolism | Membrane Proteins - genetics | Models, Molecular | Recombinant Proteins - chemistry | Neoplasm Proteins - chemistry | Proto-Oncogene Proteins - genetics | Recombinant Proteins - genetics | Proteins - genetics | Sequence Homology, Amino Acid | Carrier Proteins - genetics | Peptide Fragments - chemistry | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Proteins - metabolism | Membrane Proteins - chemistry | Models, Biological | Myeloid Cell Leukemia Sequence 1 Protein | Biosensing Techniques | Ligands | Mice | Apoptosis - physiology | Proteins - chemistry | In Vitro Techniques | Proto-Oncogene Proteins c-bcl-2 - genetics | Index Medicus
Journal Article
Structure (London), ISSN 0969-2126, 01/2018, Volume 26, Issue 1, pp. 153 - 160.e4
BCL-2 family proteins are high-priority cancer targets whose structures provide essential blueprints for drug design... 
BFL-1/A1 | BCL-2 | BCL-2 family | MCL-1 | covalent inhibitor | BIM | apoptosis | stapled peptide | BH3-only protein | NOXA | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Apoproteins - chemistry | Proto-Oncogene Proteins - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Crystallography, X-Ray | Proto-Oncogene Proteins - chemistry | Proto-Oncogene Proteins c-bcl-2 - metabolism | Cloning, Molecular | Escherichia coli - metabolism | Minor Histocompatibility Antigens - genetics | Proto-Oncogene Proteins c-bcl-2 - chemistry | Protein Interaction Domains and Motifs | Binding Sites | Apoproteins - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Protein Conformation, alpha-Helical | Apoproteins - antagonists & inhibitors | Gene Expression | Genetic Vectors - chemistry | Genetic Vectors - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Antineoplastic Agents - chemistry | Peptide Fragments - chemical synthesis | Minor Histocompatibility Antigens - metabolism | Peptide Fragments - chemistry | Protein Conformation, beta-Strand | Escherichia coli - genetics | Apoproteins - genetics | Hydrophobic and Hydrophilic Interactions | Protein Binding | Ligands | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Proto-Oncogene Proteins c-bcl-2 - genetics | Minor Histocompatibility Antigens - chemistry | Proteins | Cysteine | Analysis | Crystals | Structure | Cystine | Apoptosis | Index Medicus | BFL-1
Journal Article
Journal Article
Cell (Cambridge), ISSN 0092-8674, 09/2005, Volume 122, Issue 6, pp. 927 - 939
Journal Article
Nature medicine, ISSN 1546-170X, 01/2013, Volume 19, Issue 2, pp. 202 - 208
Journal Article