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Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7547, pp. 368 - 372
Drug resistance invariably limits the clinical efficacy of targeted therapy with kinase inhibitors against cancer(1,2). Here we show that targeted therapy with... 
CNS CELL-TYPES | MELANOMA | METASTASIS | MICROENVIRONMENT | TRANSLATIONAL PROFILING APPROACH | MULTIDISCIPLINARY SCIENCES | RAF INHIBITOR RESISTANCE | ACQUIRED-RESISTANCE | KINASE INHIBITORS | DRUG-RESISTANCE | CANCER CHEMORESISTANCE | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | Clone Cells - drug effects | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Proto-Oncogene Proteins c-fos - deficiency | Adenocarcinoma - metabolism | Neoplasm Metastasis - drug therapy | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Female | Proto-Oncogene Proteins c-akt - metabolism | Melanoma - metabolism | Tumor Microenvironment - drug effects | Cell Survival - drug effects | Melanoma - pathology | Down-Regulation - drug effects | Enzyme Activation - drug effects | Adenocarcinoma - drug therapy | Disease Progression | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Cell Movement - drug effects | Lung Neoplasms - secretion | Melanoma - secretion | Animals | Clone Cells - pathology | Metabolome - drug effects | Signal Transduction - drug effects | Neoplasm Metastasis - pathology | Protein Kinase Inhibitors - therapeutic use | Melanoma - drug therapy | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Adenocarcinoma - secretion | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Drug Resistance, Neoplasm - drug effects | Antimitotic agents | Pharmaceutical research | Care and treatment | Oncology, Experimental | Dosage and administration | Research | Drug therapy | Drug resistance | Antineoplastic agents | Tumors | Cancer | Melanoma | Mutation | Metastasis | Kinases | Cancer therapies
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2003, Volume 23, Issue 27, pp. 9116 - 9122
Journal Article
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2012, Volume 122, Issue 8, pp. 2898 - 2910
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 06/2002, Volume 21, Issue 27, pp. 4266 - 4276
The two calgranulins S100A8 and S100A9 were found to be differentially expressed at sites of acute and chronic inflammation. Here we have employed the phorbol... 
Epidermis | Papilloma | Inflammation | Tumor promoter | AP-1 | CALCIUM-BINDING PROTEINS | MOUSE KERATINOCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | RECEPTOR | MRP14 | CELL BIOLOGY | GENE | ONCOLOGY | inflammation | papilloma | GENETICS & HEREDITY | tumor promoter | DIFFERENTIATION | MALIGNANT PROGRESSION | EXPRESSION | epidermis | Calgranulin B | Tetradecanoylphorbol Acetate - pharmacology | Calgranulin A | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - chemically induced | Carcinogens - toxicity | Proto-Oncogene Proteins c-fos - deficiency | S100 Proteins - genetics | Calcium - physiology | Carcinogens - pharmacology | Dexamethasone - pharmacology | Genes, fos | Female | Gene Expression Regulation, Neoplastic - drug effects | S100 Proteins - biosynthesis | Drug Eruptions - genetics | Papilloma - chemically induced | Papilloma - metabolism | Drug Eruptions - etiology | Papilloma - genetics | Calcium-Binding Proteins - biosynthesis | Specific Pathogen-Free Organisms | Antineoplastic Agents, Hormonal - pharmacology | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | Protein Kinase C - antagonists & inhibitors | Skin Neoplasms - chemically induced | Mice, Inbred Strains | Disease Progression | Mice, Knockout | Skin Neoplasms - metabolism | Gene Expression Regulation - drug effects | Drug Eruptions - metabolism | Antigens, Differentiation - biosynthesis | Animals | Tetradecanoylphorbol Acetate - toxicity | Keratinocytes - drug effects | Keratinocytes - metabolism | Skin Neoplasms - genetics | Transcription Factor AP-1 - physiology | Leukocytes - drug effects | Antigens, Differentiation - genetics | Mice | Leukocytes - metabolism | Proto-Oncogene Proteins c-fos - physiology | Calcium-Binding Proteins - genetics
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 06/2005, Volume 174, Issue 12, pp. 7703 - 7710
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 11/2000, Volume 14, Issue 21, pp. 2695 - 2700
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 04/2013, Volume 38, Issue 5, pp. 895 - 906
Patients with epilepsy are at high risk for major depression relative to the general population, and both disorders are associated with changes in adult... 
epilepsy | adult neurogenesis | immediate early gene | neural progenitor | alternative splicing | proliferation | TGF-BETA | INCREASED EXPRESSION | PSYCHIATRY | TRANSCRIPTION | INDUCTION | NEUROSCIENCES | DELTA-FOSB | NEUROPEPTIDE VGF | SEIZURES | GENE | GALANIN | PHARMACOLOGY & PHARMACY | BRAIN | Microtubule-Associated Proteins - metabolism | Male | Phosphopyruvate Hydratase - metabolism | Electroencephalography | Depression - genetics | Neurogenesis - genetics | Proto-Oncogene Proteins c-fos - deficiency | Microarray Analysis | Depression - complications | Epilepsy - genetics | Bromodeoxyuridine - metabolism | Disease Models, Animal | Gene Expression Regulation - genetics | Kainic Acid - pharmacology | Mice, Inbred C57BL | Mice, Transgenic | Neuropeptides - metabolism | Excitatory Amino Acid Agonists - pharmacology | Hippocampus - pathology | Mutation - genetics | Epilepsy - complications | Gene Expression Regulation - drug effects | Animals | Proto-Oncogene Proteins c-fos - genetics | Cell Proliferation - drug effects | Mice | Alternative splicing | Brain | subventricular zone | Animal models | FosB protein | Neuropathology | Epilepsy | Translation initiation | Forebrain | Depression | Gene expression | Neurogenesis | Risk factors | Immediate-early proteins | Dentate gyrus | Ischemia | Neural stem cells | Ventricle (lateral) | Hippocampus | animal models | neurogenetics | unipolar | molecular & cellular neurobiology | bipolar | depression | Original
Journal Article