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blotting, western (105) 105
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protein (102) 102
lymphocyte specific protein tyrosine kinase p56 (98) 98
phosphoproteins - metabolism (96) 96
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phosphorylation - drug effects (88) 88
cell line, tumor (86) 86
lymphocyte specific protein tyrosine kinase p56 - metabolism (85) 85
long-term potentiation (84) 84
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analysis (68) 68
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precipitin tests (64) 64
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Journal Article
Science, ISSN 0036-8075, 9/2011, Volume 333, Issue 6049, pp. 1647 - 1651
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2013, Volume 110, Issue 32, pp. 12867 - 12874
The importance of dynamics to biomolecular function is becoming increasingly clear. A description of the structure-function relationship must, therefore,... 
Proteins | Chemical equilibrium | Enzymes | Spectroscopy | Molecular structure | RNA | PERSPECTIVE | DNA | Chemical bases | Biomolecules | Nuclear magnetic resonance | Energy landscape | Invisible states | Structure-function paradigm | Transiently and sparsely populated biomolecular states | invisible states | 3-DIMENSIONAL FOURIER SYNTHESIS | MULTIDISCIPLINARY SCIENCES | NUCLEAR-MAGNETIC-RESONANCE | structure-function paradigm | CHEMICAL-EXCHANGE | X-RAY ANALYSIS | energy landscape | ON-PATHWAY INTERMEDIATE | DOMAIN FOLDING PATHWAY | FF DOMAIN | FRAME SPIN RELAXATION | DIHYDROFOLATE-REDUCTASE | RELAXATION DISPERSION NMR | transiently and sparsely populated biomolecular states | Protein Structure, Tertiary | Reproducibility of Results | Calmodulin - metabolism | Calcium - metabolism | Models, Molecular | Calcium - chemistry | Protein Folding | src Homology Domains | Proto-Oncogene Proteins c-fyn - metabolism | Nuclear Magnetic Resonance, Biomolecular - methods | Protein Binding | Protein Conformation | Proto-Oncogene Proteins c-fyn - chemistry | Calmodulin - chemistry | Nuclear magnetic resonance spectroscopy | Research | Properties | Molecular biology | Methods | Binding sites (Biochemistry) | Atoms & subatomic particles | Molecules | Nuclear magnetic resonance--NMR | Index Medicus | structure–function paradigm | Biological Sciences
Journal Article
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 02/2013, Volume 288, Issue 6, pp. 4056 - 4065
The mechanisms underlying Tau-related synaptic and cognitive deficits and the interrelationships between Tau species, their clearance pathways, and synaptic... 
DOMAIN | PROTEIN | PHOSPHORYLATION | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCIBLE MOUSE MODELS | PATHOLOGY | PLAQUES | DETERMINES AGGREGATION | RECEPTORS | OLIGOMERS | Disks Large Homolog 4 Protein | Solubility - drug effects | Tauopathies - genetics | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Tauopathies - pathology | tau Proteins - metabolism | Male | Intracellular Signaling Peptides and Proteins - metabolism | Synapses - genetics | Synapses - pathology | Proto-Oncogene Proteins c-akt - genetics | Receptors, N-Methyl-D-Aspartate - genetics | Proto-Oncogene Proteins c-fyn - genetics | Heat-Shock Proteins - genetics | Proteolysis - drug effects | Synapses - metabolism | tau Proteins - genetics | Protein Multimerization - genetics | Aged, 80 and over | Behavior, Animal - drug effects | Female | Membrane Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Membrane Proteins - genetics | Heat-Shock Proteins - metabolism | Curcumin - pharmacology | Mice, Transgenic | Hippocampus - pathology | Hippocampus - metabolism | Tauopathies - metabolism | Animals | Proto-Oncogene Proteins c-fyn - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Aged | Mice | Tauopathies - drug therapy | Protein Multimerization - drug effects | Index Medicus | Hsp90 | Molecular Bases of Disease | Neurodegenerative Diseases | Human Tau Transgenic Mice | Heat Shock Proteins | Tau | Curcumin | Tau Oligomers | Alzheimer Disease | Neurological Diseases
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2017, Volume 36, Issue 21, pp. 3120 - 3138
The cause of protein accumulation in neurodegenerative disease is incompletely understood. In Alzheimer's disease ( AD ), the axonally enriched protein Tau... 
amyloid‐β | protein synthesis | microtubule‐associated protein Tau | Src kinase Fyn | proximity ligation assay | amyloid-β | microtubule-associated protein Tau | S6 PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CEREBROSPINAL-FLUID | SYNAPTIC PLASTICITY | MOUSE MODELS | CELL BIOLOGY | amyloid-beta | COGNITIVE IMPAIRMENTS | PRION PROTEIN | MESSENGER-RNA | T-CELLS | AMYLOID-BETA OLIGOMERS | TRANSGENIC MICE | Neurons - pathology | Protein Biosynthesis | Ribosomal Protein S6 Kinases - metabolism | Embryo, Mammalian | Humans | Injections, Intraventricular | tau Proteins - metabolism | Male | Alzheimer Disease - pathology | MAP Kinase Signaling System | Proto-Oncogene Proteins c-fyn - genetics | Neurons - ultrastructure | tau Proteins - genetics | Amyloid beta-Protein Precursor - metabolism | HEK293 Cells | Puromycin - pharmacology | Neurons - metabolism | Amyloid beta-Peptides - administration & dosage | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Gene Expression Regulation | Hippocampus - pathology | Mice, Knockout | Stereotaxic Techniques | Hippocampus - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Proto-Oncogene Proteins c-fyn - metabolism | Alzheimer Disease - metabolism | Mice | Alzheimer Disease - genetics | Ribosomal Protein S6 Kinases - genetics | Phosphorylation | Translation | Neurodegenerative diseases | Extracellular signal-regulated kinase | Protein biosynthesis | Activation | Pharmacology | Agglomeration | Kinases | Accumulation | Proteins | Signal transduction | Signaling | Detachment | Clonal deletion | Tau protein | Protein synthesis | Microtubules | Deletion | β-Amyloid | Transduction | Alzheimers disease | Alzheimer's disease | Fyn protein | Index Medicus | Neuroscience | Protein Biosynthesis & Quality Control
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 10/2011, Volume 31, Issue 19, pp. 3963 - 3974
Journal Article