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index medicus (744) 744
humans (658) 658
proto-oncogene proteins c-mdm2 (359) 359
oncology (313) 313
p53 (301) 301
animals (292) 292
nuclear proteins (287) 287
tumor suppressor protein p53 - metabolism (286) 286
mdm2 (260) 260
proto-oncogene proteins - biosynthesis (243) 243
tumor suppressor protein p53 - genetics (241) 241
tumor suppressor protein p53 - biosynthesis (233) 233
female (218) 218
mice (215) 215
proto-oncogene proteins c-mdm2 - metabolism (215) 215
proto-oncogene proteins c-mdm2 - genetics (199) 199
apoptosis (197) 197
proto-oncogene proteins - genetics (193) 193
cell biology (186) 186
male (173) 173
biochemistry & molecular biology (172) 172
cell line, tumor (170) 170
cancer (149) 149
proto-oncogene proteins c-mdm2 - biosynthesis (147) 147
expression (141) 141
protein (138) 138
immunohistochemistry (121) 121
middle aged (119) 119
gene expression (109) 109
mutation (109) 109
proto-oncogene proteins - metabolism (106) 106
tumor proteins (102) 102
gene expression regulation, neoplastic (101) 101
aged (100) 100
adult (96) 96
tumor cells, cultured (96) 96
cyclin-dependent kinase inhibitor p21 (95) 95
gene (95) 95
wild-type p53 (92) 92
dna-damage (90) 90
signal transduction (89) 89
neoplasm proteins - biosynthesis (88) 88
genes, p53 (84) 84
proteins (84) 84
transfection (84) 84
activation (83) 83
genetics & heredity (78) 78
phosphorylation (77) 77
apoptosis - drug effects (76) 76
cyclins - biosynthesis (74) 74
dna damage (74) 74
tumor suppressor protein p53 - physiology (74) 74
article (71) 71
cell line (69) 69
p53 protein (69) 69
research (69) 69
neoplasm proteins - genetics (67) 67
nuclear proteins - genetics (67) 67
rna, messenger - genetics (67) 67
prognosis (65) 65
protein binding (65) 65
protein biosynthesis (65) 65
cell cycle (64) 64
cells (64) 64
in-vivo (64) 64
amplification (62) 62
mutations (62) 62
rna, messenger - metabolism (62) 62
tumors (62) 62
nuclear proteins - metabolism (60) 60
rna, messenger - biosynthesis (60) 60
pathology (59) 59
genetic aspects (57) 57
mdm2 protein (57) 57
nuclear proteins - biosynthesis (57) 57
analysis (55) 55
aged, 80 and over (53) 53
degradation (52) 52
molecular sequence data (52) 52
pathway (52) 52
proto-oncogene proteins c-mdm2 - antagonists & inhibitors (52) 52
antineoplastic agents - pharmacology (51) 51
gene-expression (51) 51
oncogene (50) 50
transcriptional activation (49) 49
inhibition (47) 47
physiological aspects (47) 47
blotting, western (46) 46
gene amplification (46) 46
transcription, genetic (46) 46
cell proliferation (45) 45
cells, cultured (45) 45
apoptosis - genetics (44) 44
apoptosis - physiology (43) 43
down-regulation (43) 43
mice, nude (43) 43
reverse transcriptase polymerase chain reaction (42) 42
health aspects (41) 41
oncoprotein mdm2 (41) 41
breast neoplasms - metabolism (40) 40
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Nature Medicine, ISSN 1078-8956, 08/2012, Volume 18, Issue 8, pp. 1239 - 1247
The inactivation of the p53 tumor suppressor pathway, which often occurs through mutations in TP53 (encoding tumor protein 53) is a common step in human... 
MEDICINE, RESEARCH & EXPERIMENTAL | N-RAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-SUPPRESSOR ACTIVITY | STAPLED P53 | BRAF | MALIGNANT-MELANOMA | P53 PATHWAY | CELL-DEATH | CELL BIOLOGY | BREAST-CANCER | METASTATIC MELANOMA | IN-VIVO | Up-Regulation | Proto-Oncogene Proteins c-mdm2 - genetics | Tumor Suppressor Protein p53 - antagonists & inhibitors | Apoptosis - drug effects | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Recombinant Fusion Proteins - physiology | Skin Neoplasms - chemistry | Male | Melanocytes - metabolism | Neoplasm Proteins - antagonists & inhibitors | Cell Line, Tumor - transplantation | Proto-Oncogene Proteins - biosynthesis | Tumor Suppressor Protein p53 - physiology | Cell-Penetrating Peptides - pharmacology | Nuclear Proteins - biosynthesis | Female | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Cell Line, Tumor - metabolism | Melanoma - chemistry | Proto-Oncogene Proteins c-mdm2 - biosynthesis | Proto-Oncogene Proteins - antagonists & inhibitors | Tumor Stem Cell Assay | Membrane Proteins - genetics | Neoplasm Proteins - biosynthesis | Melanoma, Experimental - etiology | Mice, Inbred C57BL | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Melanoma - pathology | Melanoma - secondary | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Melanoma, Experimental - genetics | GTP Phosphohydrolases - genetics | Keratinocytes - metabolism | Mice, Nude | Nuclear Proteins - antagonists & inhibitors | Proto-Oncogene Proteins - physiology | Signal Transduction - physiology | Mice | Nuclear Proteins - physiology | Drug Resistance, Neoplasm - physiology | Drug Resistance, Neoplasm - drug effects | Care and treatment | Gene mutations | Melanoma | Diagnosis | Research | Gene expression | Identification and classification | Skin cancer | Proteins | Cell growth | Mutation | Cell cycle | Index Medicus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 02/2008, Volume 10, Issue 2, pp. 138 - 148
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 01/2016, Volume 35, Issue 3, pp. 358 - 365
Journal Article
Journal of Nanoscience and Nanotechnology, ISSN 1533-4880, 07/2015, Volume 15, Issue 7, pp. 4815 - 4828
China is one of the countries with the highest incidence of gastric cancer, and accounts for over 40% of all new gastric cancer cases in the world. Genetic... 
MRNA expression | Basal excision repair (ber) | NEIL2 | Genotyping | APE1 | DNA Repair | Reactive oxygen species (ros) | MDM2 | CYP2E1 | Gastric cancer | Single nucleotide polymorphism (snp) | mRNA Expression | WASTE-WATER TREATMENT | PHYSICS, APPLIED | Reactive Oxygen Species (ROS) | MATERIALS SCIENCE, MULTIDISCIPLINARY | IN-VITRO SELECTION | BASE EXCISION-REPAIR | FUNCTIONAL MAGNETIC NANOPARTICLES | Gastric Cancer | SINGLE NUCLEOTIDE POLYMORPHISM | IRON-OXIDE NANOPARTICLES | PHYSICS, CONDENSED MATTER | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | Basal Excision Repair (BER) | THROUGHPUT GENOTYPING METHOD | POLYMERASE-CHAIN-REACTION | Single Nucleotide Polymorphism (SNP) | DUAL-COLOR HYBRIDIZATION | HUMAN DNA GLYCOSYLASE | Proto-Oncogene Proteins c-mdm2 - genetics | Humans | Middle Aged | Stomach Neoplasms - metabolism | DNA-(Apurinic or Apyrimidinic Site) Lyase - biosynthesis | Male | Stomach Neoplasms - pathology | Cytochrome P-450 CYP2E1 - genetics | Case-Control Studies | Cytochrome P-450 CYP2E1 - biosynthesis | DNA-(Apurinic or Apyrimidinic Site) Lyase - genetics | DNA Glycosylases - biosynthesis | Aged, 80 and over | Adult | Female | Stomach Neoplasms - epidemiology | Proto-Oncogene Proteins c-mdm2 - biosynthesis | Stomach Neoplasms - genetics | Genetic Predisposition to Disease | Gene Frequency | DNA Glycosylases - genetics | Gene Expression Regulation | China - epidemiology | Asian Continental Ancestry Group | Alleles | Aged | Polymorphism, Single Nucleotide | Carcinogens | Genes | Risk | Nanostructure | Gene expression | Risk analysis | Polymorphism | Cancer
Journal Article
Cancer Cell, ISSN 1535-6108, 2010, Volume 18, Issue 3, pp. 220 - 230
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 07/2013, Volume 45, Issue 7, pp. 1468 - 1478
Journal Article