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Clinical Cancer Research, ISSN 1078-0432, 08/2017, Volume 23, Issue 15, pp. 4242 - 4250
Journal Article
Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7545, pp. 57 - 62
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2012, Volume 18, Issue 8, pp. 1239 - 1247
The inactivation of the p53 tumor suppressor pathway, which often occurs through mutations in TP53 (encoding tumor protein 53) is a common step in human... 
MEDICINE, RESEARCH & EXPERIMENTAL | N-RAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-SUPPRESSOR ACTIVITY | STAPLED P53 | BRAF | MALIGNANT-MELANOMA | P53 PATHWAY | CELL-DEATH | CELL BIOLOGY | BREAST-CANCER | METASTATIC MELANOMA | IN-VIVO | Up-Regulation | Proto-Oncogene Proteins c-mdm2 - genetics | Tumor Suppressor Protein p53 - antagonists & inhibitors | Apoptosis - drug effects | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Recombinant Fusion Proteins - physiology | Skin Neoplasms - chemistry | Male | Melanocytes - metabolism | Neoplasm Proteins - antagonists & inhibitors | Cell Line, Tumor - transplantation | Proto-Oncogene Proteins - biosynthesis | Tumor Suppressor Protein p53 - physiology | Cell-Penetrating Peptides - pharmacology | Nuclear Proteins - biosynthesis | Female | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Cell Line, Tumor - metabolism | Melanoma - chemistry | Proto-Oncogene Proteins c-mdm2 - biosynthesis | Proto-Oncogene Proteins - antagonists & inhibitors | Tumor Stem Cell Assay | Membrane Proteins - genetics | Neoplasm Proteins - biosynthesis | Melanoma, Experimental - etiology | Mice, Inbred C57BL | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Melanoma - pathology | Melanoma - secondary | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Melanoma, Experimental - genetics | GTP Phosphohydrolases - genetics | Keratinocytes - metabolism | Mice, Nude | Nuclear Proteins - antagonists & inhibitors | Proto-Oncogene Proteins - physiology | Signal Transduction - physiology | Mice | Nuclear Proteins - physiology | Drug Resistance, Neoplasm - physiology | Drug Resistance, Neoplasm - drug effects | Care and treatment | Gene mutations | Melanoma | Diagnosis | Research | Gene expression | Identification and classification | Skin cancer | Proteins | Cell growth | Mutation | Cell cycle | Index Medicus
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 12/2009, Volume 27, Issue 34, pp. 5743 - 5750
Journal Article
Cancer Cell, ISSN 1535-6108, 2010, Volume 18, Issue 4, pp. 367 - 381
Journal Article
Oncogene, ISSN 0950-9232, 08/2015, Volume 34, Issue 33, pp. 4300 - 4310
Many cancers express mutant p53 proteins that have lost wild-type tumor suppressor activity and, in many cases, have acquired oncogenic functions that can... 
ACTIVATION | COMPLEX | DOMAIN | PROTEIN | ISOFORMS | P73 FUNCTION | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | P63 | CELL BIOLOGY | ONCOLOGY | GENETICS & HEREDITY | DEGRADATION | MUTATIONS | Genetic aspects | Research | Tumor proteins | Properties | Oncology, Experimental | Cancer | Mutation | Tumors | Index Medicus | Original
Journal Article
Cell, ISSN 0092-8674, 2006, Volume 126, Issue 3, pp. 503 - 514
Journal Article
Molecular Cell, ISSN 1097-2765, 2008, Volume 30, Issue 3, pp. 277 - 289
Journal Article
Nature Cell Biology, ISSN 1465-7392, 08/2015, Volume 17, Issue 8, pp. 973 - 983
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2016, Volume 22, Issue 4, pp. 868 - 876
Journal Article