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animals (359) 359
female (164) 164
mice (151) 151
proto-oncogene proteins c-mos - metabolism (139) 139
cell biology (138) 138
proto-oncogene proteins c-mos - genetics (138) 138
humans (120) 120
biochemistry & molecular biology (118) 118
molecular sequence data (112) 112
phosphorylation (98) 98
meiosis (96) 96
meiotic maturation (93) 93
xenopus (89) 89
base sequence (82) 82
proto-oncogene proteins - genetics (81) 81
oocytes - metabolism (79) 79
map kinase (76) 76
oocytes - cytology (75) 75
proto-oncogenes (71) 71
amino acid sequence (70) 70
male (69) 69
oocytes - physiology (63) 63
proto-oncogene proteins c-mos (63) 63
oncology (60) 60
oocytes (58) 58
c-mos (55) 55
cell-cycle (55) 55
developmental biology (50) 50
research (50) 50
cell cycle (49) 49
rna, messenger - metabolism (49) 49
cells, cultured (48) 48
multidisciplinary sciences (48) 48
xenopus laevis (48) 48
protein biosynthesis (47) 47
research article (46) 46
genetics & heredity (45) 45
activation (42) 42
meiosis - physiology (42) 42
mos (42) 42
oocytes - drug effects (42) 42
proto-oncogene product (42) 42
mutation (41) 41
transcription, genetic (41) 41
oocyte maturation (40) 40
cdc2 protein kinase - metabolism (39) 39
index medicus (39) 39
metaphase (39) 39
rats (39) 39
rna, messenger - genetics (39) 39
urogenital system (38) 38
calcium-calmodulin-dependent protein kinases - metabolism (36) 36
eggs (36) 36
enzyme activation (36) 36
proteins (35) 35
signal transduction (35) 35
genes, mos (34) 34
protein-serine-threonine kinases - metabolism (34) 34
proto-oncogene proteins c-mos - physiology (34) 34
reproductive biology (34) 34
rna (34) 34
xenopus-oocytes (34) 34
cloning, molecular (32) 32
embryonic structures (32) 32
gene expression (32) 32
gene expression regulation (32) 32
progesterone - pharmacology (32) 32
cytoplasmic polyadenylation (31) 31
mitosis (30) 30
proto-oncogene proteins - metabolism (30) 30
xenopus proteins - metabolism (30) 30
expression (29) 29
oncogenes (29) 29
cell division (28) 28
maturation-promoting factor (28) 28
mitogen-activated protein kinases - metabolism (28) 28
mouse oocytes (28) 28
cell line (27) 27
fertilization (27) 27
messenger-rna (27) 27
cyclin b - metabolism (26) 26
cytostatic factor (25) 25
oocyte (25) 25
oocytes - enzymology (25) 25
protein kinases - metabolism (25) 25
protein-tyrosine kinases - metabolism (25) 25
3t3 cells (24) 24
reproductive and urinary physiology (24) 24
cell cycle proteins - metabolism (23) 23
maturation (23) 23
physiological aspects (23) 23
proto-oncogene (23) 23
recombinant fusion proteins - metabolism (23) 23
xenopus proteins (23) 23
maturation-promoting factor - metabolism (22) 22
meiosis-ii (22) 22
oocytes - growth & development (22) 22
protein-tyrosine kinases - genetics (22) 22
transfection (22) 22
genetic aspects (21) 21
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Journal Article
Biology of Reproduction, ISSN 0006-3363, 02/2008, Volume 78, Issue 2, pp. 218 - 233
Maturation of immature bovine oocytes requires cytoplasmic polyadenylation and synthesis of a number of proteins involved in meiotic progression and metaphase-II arrest... 
Gamete biology | Aurora kinases | Bovine | CPEB | Meiosis | Oocyte development | Kinases | Oocyte | MESSENGER-RNA TRANSLATION | meiosis | PARTHENOGENETIC ACTIVATION | MAP KINASE | oocyte development | CHROMOSOME CONDENSATION | gamete biology | REPRODUCTIVE BIOLOGY | kinases | oocyte | IN-VITRO MATURATION | CPEB PHOSPHORYLATION | II TRANSITION | MOUSE OOCYTES | GENE-EXPRESSION | bovine | XENOPUS-OOCYTES | Protein-Serine-Threonine Kinases - analysis | Nitriles - pharmacology | mRNA Cleavage and Polyadenylation Factors - metabolism | Cytoplasm - metabolism | RNA, Messenger - metabolism | Cyclin B1 | Embryo, Mammalian - metabolism | Aurora Kinase A | CDC2 Protein Kinase - metabolism | Proto-Oncogene Proteins c-mos - genetics | Aurora Kinase B | Aurora Kinase C | Meiosis - drug effects | Cyclin B - genetics | Cattle | Female | Proto-Oncogene Proteins c-mos - metabolism | mRNA Cleavage and Polyadenylation Factors - genetics | Protein-Serine-Threonine Kinases - metabolism | Cytoplasm - chemistry | mRNA Cleavage and Polyadenylation Factors - analysis | Butadienes - pharmacology | CDC2 Protein Kinase - genetics | Oocytes - growth & development | Fertilization | Oocytes - metabolism | Purines - pharmacology | Metformin - pharmacology | Oocytes - chemistry | Protein-Serine-Threonine Kinases - genetics | Aurora Kinases | Piperazines - pharmacology | Proto-Oncogene Proteins c-mos - analysis | Cyclin B - analysis | Animals | Polyadenylation | CDC2 Protein Kinase - analysis | Cyclin B - metabolism | Protein Kinase Inhibitors - pharmacology | CDC2 Protein Kinase | Piperazines | Embryo, Mammalian | Protein-Serine-Threonine Kinases | Proto-Oncogene Proteins c-mos | Butadienes | Cellular Biology | Oocytes | Life Sciences | Purines | Protein Kinase Inhibitors | Cyclin B | Nitriles | Metformin | RNA, Messenger | mRNA Cleavage and Polyadenylation Factors | Cytoplasm | Reproductive Biology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2014, Volume 111, Issue 52, pp. 18661 - 18666
...) and thus represent a dependency in NSCLCs harboring these alterations, but the genetic basis of EGFR dependence is not fully understood... 
Genes | Epidermal cells | Cell lines | Open reading frames | Growth factor receptors | Viability | Genetic mutation | Genetic screening | Cells | Lung neoplasms | ORF | Epidermal growth factor receptor | Non-small cell lung cancer | non-small cell lung cancer | TARGETED THERAPY | WILD-TYPE | GEFITINIB | epidermal growth factor receptor | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | KINASE INHIBITORS | TYROSINE KINASES | GROWTH-FACTOR RECEPTOR | ERLOTINIB RESISTANCE | MUTATIONS | C-SRC | Receptor, Epidermal Growth Factor - genetics | Receptor, trkB | Humans | Membrane Glycoproteins - biosynthesis | Receptor Protein-Tyrosine Kinases - biosynthesis | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Receptor, Fibroblast Growth Factor, Type 1 - genetics | MAP Kinase Signaling System | Proto-Oncogene Proteins c-mos - genetics | Receptor, trkA - biosynthesis | Protein-Tyrosine Kinases - genetics | Protein-Tyrosine Kinases - biosynthesis | Proto-Oncogene Proteins c-raf - biosynthesis | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Receptor, Epidermal Growth Factor - biosynthesis | Lung Neoplasms - enzymology | Proto-Oncogene Proteins c-raf - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Membrane Glycoproteins - genetics | Receptor, Fibroblast Growth Factor, Type 2 - biosynthesis | Gene Expression Regulation, Enzymologic | Receptor Protein-Tyrosine Kinases - genetics | Cell Line, Tumor | Receptor, trkA - genetics | Carcinoma, Non-Small-Cell Lung - enzymology | Proto-Oncogene Proteins c-mos - biosynthesis | Receptor, Fibroblast Growth Factor, Type 1 - biosynthesis | Receptor, Fibroblast Growth Factor, Type 2 - genetics | Protein research | Oncology, Experimental | Genetic aspects | Research | Lung cancer, Non-small cell | Gene expression | Cancer | Biological Sciences
Journal Article
Molecular Phylogenetics and Evolution, ISSN 1055-7903, 10/1998, Volume 10, Issue 2, pp. 259 - 263
Journal Article
The EMBO Journal, ISSN 0261-4189, 05/1996, Volume 15, Issue 10, pp. 2582 - 2592
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 07/2008, Volume 10, Issue 7, pp. 858 - 865
Journal Article
Leukemia, ISSN 0887-6924, 01/2008, Volume 22, Issue 1, pp. 138 - 146
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 08/2002, Volume 21, Issue 15, pp. 4026 - 4036
In Xenopus oocytes, the c‐mos proto‐oncogene product has been proposed to act downstream of progesterone to control the entry into meiosis I, the transition from meiosis I to meiosis II, which is characterized by the absence of S phase... 
mos | Xenopus | oocyte | proto‐oncogene | cdc2 | Mos | Oocyte | Proto-oncogene | Cdc2 | C-MOS | ACTIVATED PROTEIN-KINASE | MAP KINASE | CYCLIN-B | BIOCHEMISTRY & MOLECULAR BIOLOGY | METAPHASE-II ARREST | MAMMALIAN SOMATIC-CELLS | CELL BIOLOGY | CYTOSTATIC FACTOR ACTIVITY | proto-oncogene | MEIOSIS-II | MOUSE OOCYTES | ONCOGENE PRODUCT | Protein Kinases - metabolism | Meiosis - physiology | Oligodeoxyribonucleotides, Antisense - pharmacology | Species Specificity | Xenopus Proteins - genetics | Oogenesis - physiology | Recombinant Fusion Proteins - physiology | Cyclin B2 | Proto-Oncogene Proteins c-mos - physiology | Genetic Complementation Test | Ribosomal Protein S6 Kinases | MAP Kinase Signaling System | CDC2 Protein Kinase - metabolism | Proto-Oncogene Proteins c-mos - genetics | Oocytes - cytology | Meiosis - drug effects | Egg Proteins - physiology | Proto-Oncogene Proteins c-mos - deficiency | Oocytes - drug effects | Female | Oogenesis - drug effects | Xenopus laevis - genetics | Oocytes - metabolism | Morpholines - pharmacology | DNA Replication | Oogenesis - genetics | Meiosis - genetics | Animals | Xenopus Proteins - deficiency | Xenopus Proteins - physiology | Cyclin B - metabolism | Protein Biosynthesis - drug effects | Enzyme Activation | Xenopus laevis - physiology | Egg Proteins - genetics | Life Sciences | Cellular Biology | Reproductive Biology
Journal Article