X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (18017) 18017
Publication (2202) 2202
Book Review (1716) 1716
Book Chapter (85) 85
Conference Proceeding (40) 40
Dissertation (19) 19
Book / eBook (9) 9
Reference (1) 1
Streaming Video (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (17513) 17513
humans (13398) 13398
animals (9442) 9442
mice (6043) 6043
proto-oncogene proteins c-myc - genetics (5524) 5524
oncology (5190) 5190
proto-oncogene proteins c-myc - metabolism (5023) 5023
cell biology (4824) 4824
c-myc (4367) 4367
biochemistry & molecular biology (4142) 4142
female (3907) 3907
apoptosis (3806) 3806
expression (3773) 3773
cell line, tumor (3436) 3436
male (3379) 3379
cancer (3372) 3372
gene expression (3000) 3000
proto-oncogene proteins - genetics (2554) 2554
signal transduction (2488) 2488
proteins (2405) 2405
gene expression regulation, neoplastic (2363) 2363
cell proliferation (2151) 2151
research (2116) 2116
cell line (2103) 2103
phosphorylation (1909) 1909
genetic aspects (1758) 1758
activation (1681) 1681
transfection (1617) 1617
cells, cultured (1611) 1611
molecular sequence data (1608) 1608
middle aged (1572) 1572
tumor cells, cultured (1565) 1565
genetics & heredity (1552) 1552
gene (1536) 1536
mutation (1528) 1528
rats (1515) 1515
tumors (1514) 1514
base sequence (1509) 1509
gene-expression (1508) 1508
cell cycle (1501) 1501
proto-oncogene proteins - metabolism (1486) 1486
gene expression regulation (1462) 1462
rna, messenger - genetics (1462) 1462
article (1460) 1460
genes (1423) 1423
cells (1398) 1398
apoptosis - drug effects (1390) 1390
transcription, genetic (1364) 1364
protein (1324) 1324
multidisciplinary sciences (1317) 1317
adult (1313) 1313
rna, messenger - metabolism (1312) 1312
immunohistochemistry (1310) 1310
proto-oncogene proteins c-akt - metabolism (1256) 1256
analysis (1246) 1246
proliferation (1237) 1237
aged (1236) 1236
myc (1231) 1231
proto-oncogenes (1230) 1230
differentiation (1227) 1227
growth (1214) 1214
genes, myc (1206) 1206
physiological aspects (1194) 1194
promoter regions, genetic (1138) 1138
transcription (1125) 1125
blotting, western (1109) 1109
transcription factors - metabolism (1087) 1087
research article (1084) 1084
hematology (1082) 1082
prognosis (1078) 1078
oncogenes (1075) 1075
down-regulation (1061) 1061
proto-oncogene proteins c-myc - biosynthesis (1057) 1057
transcription factors (1054) 1054
transcription factors - genetics (1016) 1016
reverse transcriptase polymerase chain reaction (1007) 1007
in-vivo (1004) 1004
dna-binding proteins - metabolism (998) 998
mice, transgenic (998) 998
dna-binding proteins - genetics (996) 996
kinases (986) 986
cell proliferation - drug effects (976) 976
protein binding (976) 976
cell differentiation (971) 971
health aspects (967) 967
p53 (954) 954
proto-oncogene proteins c-bcl-2 - metabolism (949) 949
biology (944) 944
abridged index medicus (929) 929
proto-oncogene proteins c-bcl-2 - genetics (903) 903
tumor suppressor protein p53 - metabolism (886) 886
cell growth (880) 880
dna (867) 867
medicine (850) 850
mice, nude (842) 842
amino acid sequence (830) 830
stem cells (827) 827
inhibition (819) 819
rna interference (810) 810
mice, inbred c57bl (808) 808
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (17711) 17711
Chinese (196) 196
Japanese (49) 49
Russian (25) 25
German (23) 23
French (22) 22
Spanish (6) 6
Polish (4) 4
Czech (2) 2
Hungarian (2) 2
Italian (2) 2
Portuguese (2) 2
Serbian (2) 2
Croatian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2014, Volume 111, Issue 52, pp. 18697 - 18702
Journal Article
Cell, ISSN 0092-8674, 2011, Volume 146, Issue 6, pp. 904 - 917
Journal Article
Blood, ISSN 0006-4971, 10/2012, Volume 120, Issue 14, pp. 2843 - 2852
We investigated the therapeutic potential of JQ1, an inhibitor of the BET class of human bromodomain proteins, in B-cell acute lymphoblastic leukemia (B-ALL).... 
SELECTIVE-INHIBITION | REARRANGEMENT | TRANSLOCATION | PROTEIN | OF-FUNCTION MUTATIONS | HUMAN CANCERS | HEMATOLOGY | EXPRESSION | CELL-LINE | B-PROGENITOR | CRLF2 | Cell Proliferation | Oligonucleotide Array Sequence Analysis | Humans | Gene Expression Profiling | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Receptors, Interleukin-7 - genetics | Flow Cytometry | Chromatin Immunoprecipitation | Janus Kinase 2 - metabolism | Biomarkers, Tumor - metabolism | B-Lymphocytes - pathology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Real-Time Polymerase Chain Reaction | Receptors, Cytokine - genetics | Triazoles - therapeutic use | Receptors, Interleukin-7 - metabolism | RNA, Messenger - genetics | Risk Factors | Janus Kinase 2 - genetics | Transcription Factors - antagonists & inhibitors | Reverse Transcriptase Polymerase Chain Reaction | Proto-Oncogene Proteins c-myc - metabolism | Blotting, Western | Azepines - therapeutic use | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Xenograft Model Antitumor Assays | Animals | Gene Rearrangement | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mice, Inbred NOD | Biomarkers, Tumor - genetics | Mice | Proto-Oncogene Proteins c-myc - genetics | Apoptosis | Index Medicus | Abridged Index Medicus | Lymphoid Neoplasia
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 25, pp. 9157 - 9162
The transcription factor c-MYC is stabilized and activated by phosphorylation at serine 62 (S62) in breast cancer. Protein phosphatase 2A (PP2A) is a critical... 
Tumor cell line | Cell growth | Cell lines | Small interfering RNA | Breast cancer | Breast neoplasms | Heterologous transplantation | Tumors | Cancer | Apoptosis | Breast cancer therapy | Phosphatase activator | TUMOR-SUPPRESSOR PP2A | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | PROTEIN PHOSPHATASE 2A | CIP2A | OVEREXPRESSION | phosphatase activator | CELL-TRANSFORMATION | GENE | breast cancer therapy | MYELOID-LEUKEMIA | DEGRADATION | SUBUNIT | Gene Expression Regulation, Enzymologic - drug effects | Autoantigens - biosynthesis | Histone Chaperones - genetics | Humans | Autoantigens - genetics | Breast Neoplasms - metabolism | Drug Delivery Systems | Gene Knockdown Techniques | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - genetics | Protein Phosphatase 2 - antagonists & inhibitors | Membrane Proteins - genetics | Enzyme Inhibitors - pharmacology | Protein Phosphatase 2 - genetics | Transcription Factors - biosynthesis | Transcription Factors - genetics | Breast Neoplasms - drug therapy | Proto-Oncogene Proteins c-myc - metabolism | Membrane Proteins - biosynthesis | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Gene Expression Regulation, Enzymologic - genetics | Histone Chaperones - biosynthesis | Protein Phosphatase 2 - metabolism | Cell Line, Tumor | Proto-Oncogene Proteins c-myc - genetics | Physiological aspects | Tumor suppressor genes | Care and treatment | Transcription factors | Genetic aspects | Phosphorylation | Gene expression | Cells | Index Medicus | Biological Sciences
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2016, Volume 64, Issue 4, pp. 774 - 789
For many years, a connection between circadian clocks and cancer has been postulated. Here we describe an unexpected function for the circadian repressor CRY2... 
MYC | circadian rhythm | CRY2 | cryptochrome | FBXL3 | circadian clock | ubiquitin | CIRCADIAN CLOCK | CRYPTOCHROME | PROTEIN | UBIQUITIN LIGASE | TUMOR SUPPRESSION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | GENE-EXPRESSION | CANCER-RISK | FACTOR PERIOD 2 | CELL BIOLOGY | Humans | Gene Expression Regulation, Neoplastic | Cryptochromes - genetics | Circadian Clocks - genetics | Lymphoma - mortality | Lymphoma - metabolism | S-Phase Kinase-Associated Proteins - chemistry | Cell Transformation, Neoplastic - genetics | Proteolysis | HEK293 Cells | Cullin Proteins - metabolism | Fibroblasts | Carrier Proteins - chemistry | Lymphoma - pathology | Protein Stability | Cryptochromes - metabolism | Protein Structure, Secondary | Signal Transduction | F-Box Proteins - metabolism | F-Box Proteins - chemistry | Circadian Rhythm - genetics | Lymphoma - genetics | Models, Molecular | S-Phase Kinase-Associated Proteins - metabolism | Cell Transformation, Neoplastic - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Mice, Knockout | Cullin Proteins - chemistry | Cullin Proteins - genetics | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Survival Analysis | S-Phase Kinase-Associated Proteins - genetics | Cryptochromes - chemistry | Mice | Proto-Oncogene Proteins c-myc - genetics | Cell Transformation, Neoplastic - pathology | Proto-Oncogene Proteins c-myc - chemistry | F-Box Proteins - genetics | Ubiquitin | Physiological aspects | Drug discovery | Research institutes | Ligases | Index Medicus | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cell and Molecular Biology | Medicinska och farmaceutiska grundvetenskaper | Cell- och molekylärbiologi
Journal Article