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Journal Article
Oncogene, ISSN 0950-9232, 06/2016, Volume 35, Issue 26, pp. 3476 - 3484
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 7, pp. 3333 - 3345
Journal Article
Molecular Immunology, ISSN 0161-5890, 07/2012, Volume 51, Issue 3-4, pp. 255 - 262
► Notch signaling is activated in LPS/IFNγ-stimulated macrophages. ► Inhibiting Notch signaling decreased the level of mRNA and secreted IL-12p70. ► Inhibiting... 
Macrophages | Notch signaling | IL-12p40 | c-Rel | C-Rel | BIOCHEMISTRY & MOLECULAR BIOLOGY | IMMUNOLOGY | RESPONSES | INFLAMMATION | DIFFERENTIATION | UP-REGULATION | POLARIZATION | T-CELLS | KAPPA-B ACTIVITY | REQUIREMENT | PLASTICITY | PARADIGM | Amyloid Precursor Protein Secretases - genetics | Interleukin-12 Subunit p40 - genetics | Transcriptional Activation - genetics | Receptors, Notch - metabolism | Homeodomain Proteins - metabolism | Transcriptional Activation - drug effects | Tumor Necrosis Factor-alpha - genetics | Receptors, Notch - genetics | Transcriptional Activation - immunology | Lipopolysaccharides - immunology | Proto-Oncogene Proteins c-rel - immunology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-12 Subunit p40 - immunology | Interleukin-12 Subunit p40 - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Signal Transduction | Macrophage Activation - immunology | Interferon Regulatory Factors - genetics | Amyloid Precursor Protein Secretases - metabolism | Macrophages - metabolism | Mice | Receptor, Notch1 - genetics | Tumor Necrosis Factor-alpha - metabolism | Amyloid Precursor Protein Secretases - immunology | Transcription Factor HES-1 | Macrophage Activation - genetics | Interferon Regulatory Factors - metabolism | Proto-Oncogene Proteins c-rel - metabolism | Homeodomain Proteins - immunology | MAP Kinase Signaling System | Female | Interleukin-12 Subunit p40 - biosynthesis | Macrophages - immunology | Cell Line | Mice, Inbred C57BL | RNA, Messenger - genetics | Receptor, Notch1 - immunology | Receptor, Notch1 - metabolism | Homeodomain Proteins - genetics | Interferon Regulatory Factors - immunology | Animals | Proto-Oncogene Proteins c-rel - genetics | Interferon-gamma - immunology | Basic Helix-Loop-Helix Transcription Factors - immunology | Macrophages - drug effects | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Macrophage Activation - drug effects | Receptors, Notch - immunology | Antigens | Messenger RNA | RNA | Dimethyl sulfoxide | Universities and colleges | Biological response modifiers | Mitogens | macrophages
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2010, Volume 42, Issue 12, pp. 1126 - +
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 02/2013, Volume 210, Issue 2, pp. 269 - 285
Acquisition of self-tolerance in the thymus requires T cells to discriminate strong versus weak T cell receptor binding by self-peptide-MHC complexes. We find... 
DEVELOPING THYMOCYTES | MEDICINE, RESEARCH & EXPERIMENTAL | TISSUE-RESTRICTED ANTIGENS | SELF-PEPTIDE | RECEPTOR TRANSGENIC MICE | IN-VIVO | BIM | NEGATIVE SELECTION | C-MYC | CLONAL DELETION | IMMUNOLOGY | EXPRESSION | Autoimmunity | Cell Proliferation | NF-kappa B - immunology | Proto-Oncogene Proteins c-rel - metabolism | Proto-Oncogene Proteins - biosynthesis | Proto-Oncogene Proteins c-rel - immunology | CARD Signaling Adaptor Proteins - genetics | CD4-Positive T-Lymphocytes - immunology | Membrane Proteins - deficiency | CARD Signaling Adaptor Proteins - metabolism | Bcl-2-Like Protein 11 | Receptors, CCR7 - metabolism | Apoptosis Regulatory Proteins - deficiency | Programmed Cell Death 1 Receptor - biosynthesis | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Transcription Factors - immunology | Apoptosis Regulatory Proteins - biosynthesis | CARD Signaling Adaptor Proteins - immunology | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Lymphocyte Activation | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Self Tolerance | Membrane Proteins - immunology | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Transcription Factors - biosynthesis | Proto-Oncogene Proteins - deficiency | Clonal Deletion - immunology | Mice, Knockout | Membrane Proteins - biosynthesis | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-rel - genetics | NF-kappa B - biosynthesis | Mice | Mutation | Programmed Cell Death 1 Receptor - immunology | DNA-Binding Proteins - biosynthesis | 309
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2015, Volume 194, Issue 6, pp. 2472 - 2476
Journal Article