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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2009, Volume 106, Issue 44, pp. 18740 - 18744
The transcription factor gene MYB was identified recently as an oncogene that is rearranged/duplicated in some human leukemias. Here we describe a new... 
Head | MicroRNA | Transfection | Salivary glands | Exons | Genes | Cell lines | Oncogenes | Adenoid cystic carcinoma | Tumors | miRNA | Fusion oncogene | Chromosome translocation | TARGET | TRANSLOCATION | MULTIDISCIPLINARY SCIENCES | fusion oncogene | chromosome translocation | C-MYB | LET-7 | adenoid cystic carcinoma | IDENTIFICATION | REARRANGEMENTS | DIFFERENTIATION | CELL | EXPRESSION | Chromosomes, Human, Pair 8 - genetics | Translocation, Genetic | Oncogene Proteins, Fusion - metabolism | Carcinoma, Adenoid Cystic - pathology | Leukemia-Lymphoma, Adult T-Cell - genetics | Humans | Middle Aged | RNA, Messenger - genetics | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Male | RNA, Messenger - metabolism | Chromosomes, Human, Pair 6 - genetics | Head and Neck Neoplasms - pathology | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Carcinoma, Adenoid Cystic - genetics | Oncogene Proteins, Fusion - genetics | Base Sequence | Adult | Female | Head and Neck Neoplasms - genetics | Aged | MicroRNAs - genetics | Evaluation | Adenoids | Carcinoma | Physiological aspects | Properties | Gene expression | Cancer | Proto-oncogenes | Proteins | Leukemia | Breast cancer | Head & neck cancer | Cells | Index Medicus | Biological Sciences | MicroRNAs/genetics | Pair 8/genetics | RNA | Oncogene Proteins | Genetic | Adult T-Cell/genetics | Pair 6/genetics | Breast Neoplasms/genetics/pathology | Chromosomes | Human | Translocation | Messenger/genetics/metabolism | Gene Expression Regulation | Cell and Molecular Biology | Head and Neck Neoplasms/genetics/pathology | Leukemia-Lymphoma | Adenoid Cystic/genetics/pathology | Fusion/genetics/metabolism | Neoplastic | Cell- och molekylärbiologi
Journal Article
Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7413, pp. 660 - 664
Journal Article
Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7409, pp. 106 - 110
Medulloblastomas are themost commonmalignant brain tumours in children(1). Identifying and understanding the genetic events that drive these tumours is... 
COMPLEX | STRUCTURAL BASIS | LANDSCAPE | CHILDHOOD | MULTIDISCIPLINARY SCIENCES | GENES | Transcription Factors - chemistry | Humans | Hedgehog Proteins - metabolism | Wnt Proteins - metabolism | Promoter Regions, Genetic - genetics | Tumor Suppressor Protein p53 - genetics | TCF Transcription Factors - metabolism | Patched Receptors | Cerebellar Neoplasms - classification | DEAD-box RNA Helicases - metabolism | Medulloblastoma - genetics | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Child | DEAD-box RNA Helicases - chemistry | DNA Helicases - genetics | Intracellular Signaling Peptides and Proteins - genetics | DNA Helicases - chemistry | Histone-Lysine N-Methyltransferase - genetics | Signal Transduction | Models, Molecular | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | Protein Structure, Tertiary - genetics | Cerebellar Neoplasms - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Nuclear Proteins - chemistry | beta Catenin - metabolism | Genome, Human - genetics | beta Catenin - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Histone Methyltransferases | Histone-Lysine N-Methyltransferase - metabolism | LIM Domain Proteins - genetics | Medulloblastoma - classification | Patched-1 Receptor | Receptors, Cell Surface - genetics | Medulloblastoma | Physiological aspects | Development and progression | Genetic aspects | Research | Nucleotide sequencing | Metastasis | DNA sequencing | Cancer | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7339, pp. 467 - 472
Multiple myeloma is an incurable malignancy of plasma cells, and its pathogenesis is poorly understood. Here we report the massively parallel sequencing of 38... 
PATHOGENESIS | B-CELL LYMPHOMA | BLIMP-1 | GENE | MULTIDISCIPLINARY SCIENCES | STRESS-RESPONSE | EXOSOME | CLASSIFICATION | DIFFERENTIATION | HUMAN CANCER | SOMATIC MUTATIONS | Ribonucleases - genetics | Ribonucleases - chemistry | Genomics | Humans | Molecular Sequence Data | NF-kappa B - metabolism | DNA Repair - genetics | Multiple Myeloma - drug therapy | DNA Mutational Analysis | Protein Biosynthesis - genetics | Multiple Myeloma - enzymology | Proto-Oncogene Proteins B-raf - metabolism | Amino Acid Sequence | Oncogenes - genetics | Models, Molecular | Exons - genetics | Signal Transduction - genetics | Multiple Myeloma - metabolism | Mutation - genetics | Open Reading Frames - genetics | Genome, Human - genetics | Homeodomain Proteins - genetics | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | RNA Processing, Post-Transcriptional - genetics | Proto-Oncogene Proteins B-raf - genetics | CpG Islands - genetics | Blood Coagulation - genetics | Protein Conformation | Histones - metabolism | Transcription, Genetic - genetics | Exosome Multienzyme Ribonuclease Complex | Methylation | Homeostasis - genetics | Multiple Myeloma - genetics | Usage | Multiple myeloma | Development and progression | Genetic aspects | Research | Nucleotide sequencing | Methods | Cancer | Proteins | Pathogenesis | Homeostasis | Genetics | Genomes | Mutation | Kinases | Mass spectrometry | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, pp. 6744 - 6744
Pancreatic ductal adenocarcinoma (PDA) has a dismal prognosis and insights into both disease etiology and targeted intervention are needed. A total of 109... 
SIGNATURES | MODELS | DUCTAL ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | TUMOR | SOMATIC MUTATION | COPY-NUMBER ALTERATION | GENOMIC CHARACTERIZATION | CARCINOMA | PROGRESSION | DISCOVERY | Cell Cycle - genetics | RNA-Binding Proteins - genetics | Prognosis | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Middle Aged | Carcinoma, Adenosquamous - drug therapy | Male | Antineoplastic Agents - therapeutic use | DNA Repair - genetics | Molecular Targeted Therapy | Tumor Suppressor Protein p53 - genetics | Carcinoma, Pancreatic Ductal - genetics | DNA Copy Number Variations | Genetic Variation | Pancreatic Neoplasms - drug therapy | Aged, 80 and over | Adult | Female | Nuclear Proteins - genetics | Carcinoma, Adenosquamous - pathology | Pancreatic Neoplasms - pathology | Kaplan-Meier Estimate | Pancreatic Neoplasms - genetics | Carcinoma, Adenosquamous - genetics | Transcription Factors - genetics | Carcinoma, Pancreatic Ductal - pathology | Sequence Analysis, DNA | Carcinoma, Pancreatic Ductal - drug therapy | Drug Resistance, Neoplasm - genetics | Exome - genetics | Gene Amplification | Sulfonamides - therapeutic use | Wnt Signaling Pathway - genetics | Proto-Oncogene Proteins B-raf - genetics | Retinoblastoma Protein - genetics | Genes, myc - genetics | Indoles - therapeutic use | Aged | BRCA2 Protein - genetics | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7536, pp. 583 - 588
Journal Article
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, pp. 6691 - 6691
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7488, pp. 371 - 375
Cervical cancer is responsible for 10-15% of cancer-related deaths in women worldwide(1,2). The aetiological role of infection with high-risk human papilloma... 
DOMAIN | CATALOG | FUSION | MULTIDISCIPLINARY SCIENCES | FRAMEWORK | HUMAN-PAPILLOMAVIRUS | SENSITIVE DETECTION | CANCER | EXPRESSION | SOMATIC MUTATIONS | DISCOVERY | F-Box-WD Repeat-Containing Protein 7 | Receptor, ErbB-2 - genetics | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - virology | Genomics | Humans | E1A-Associated p300 Protein - genetics | Core Binding Factor beta Subunit - genetics | Case-Control Studies | Papillomaviridae - genetics | Tumor Suppressor Protein p53 - genetics | DNA Mutational Analysis | Mitogen-Activated Protein Kinase 1 - genetics | Cell Cycle Proteins - genetics | Female | NF-E2-Related Factor 2 - genetics | Adenocarcinoma - genetics | Papillomaviridae - physiology | HLA-B Antigens - genetics | Gene Expression Regulation, Neoplastic - genetics | Proto-Oncogene Proteins c-ets | Virus Integration - genetics | Proto-Oncogene Proteins - genetics | DNA Copy Number Variations - genetics | Transcriptome - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Uterine Cervical Neoplasms - genetics | Adenocarcinoma - virology | Genome, Human - genetics | Papillomavirus Infections - genetics | Exome - genetics | Uterine Cervical Neoplasms - virology | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Prevention | Gene mutations | Oncology, Experimental | Exome sequencing | Genetic aspects | Research | Cervical cancer | Cancer | Human papillomavirus | Mutation | Index Medicus
Journal Article