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Endocrinology, ISSN 0013-7227, 11/2015, Volume 156, Issue 11, pp. 3937 - 3949
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 09/2014, Volume 111, Issue 39, pp. E4110 - E4118
Journal Article
Obesity, ISSN 1930-7381, 03/2014, Volume 22, Issue 3, pp. 705 - 712
Objective: Obese leptin deficient (ob/ob) mice are a model of adiposity that displays increased levels of fat, glucose, and liver lipids. Our hypothesis is... 
IMPROVES INSULIN SENSITIVITY | OBESITY | NUTRITION & DIETETICS | ACTIVATED PROTEIN-KINASE | METABOLISM | GENE | OXYGENASE-1 | PGC-1-ALPHA | ENDOCRINOLOGY & METABOLISM | REV-ERB-ALPHA | STEATOHEPATITIS | ADIPOSE-TISSUE | Protoporphyrins - administration & dosage | Heme Oxygenase-1 - metabolism | Heme - metabolism | Obesity - drug therapy | Leptin - metabolism | Fibroblast Growth Factors - genetics | Mesoporphyrins - administration & dosage | Glucose Transporter Type 1 - metabolism | Male | Fibroblast Growth Factors - metabolism | Heme Oxygenase-1 - genetics | Glycogen - metabolism | Liver - drug effects | Weight Gain - drug effects | Membrane Proteins - metabolism | Fatty Liver - metabolism | Membrane Proteins - genetics | Liver - metabolism | PPAR alpha - genetics | Transcription Factors - genetics | Obesity - metabolism | Tin Compounds - administration & dosage | Transcription Factors - metabolism | Animals | Glucose Transporter Type 1 - genetics | Mice, Obese | Adiposity - physiology | Mice | PPAR alpha - metabolism | Obesity | Oxidative stress | Phosphorylation | Liver | Lipids | Glucose | Metabolism | Insulin | Proteins | Weight control | Rodents | Epigenetics | Insulin resistance | Diabetes | Index Medicus | non-alcoholic fatty liver disease (NAFLD) | PPARα | non-alcoholic steatohepatitis (NASH) | obesity | FGF21 | Heme, PGC-1α, heme oxygenase
Journal Article
Plant Physiology, ISSN 0032-0889, 5/2013, Volume 162, Issue 1, pp. 63 - 73
The NADPH-dependent thioredoxin reductase C (NTRC) is involved in redox-related regulatory processes in chloroplasts and nonphotosynthetic active plastids.... 
Proteins | Enzymes | Chloroplasts | Tetrapyrroles | Biosynthesis | Plants | Physiological regulation | BIOCHEMISTRY AND METABOLISM | Thioredoxin | Plastids | Seedlings | REDOX-MODIFICATION | ARABIDOPSIS-THALIANA | PROTEIN | CHLOROPHYLL BIOSYNTHESIS | MAGNESIUM CHELATASE | LIGHT | PROTOPORPHYRIN-IX METHYLTRANSFERASE | CHLOROPLAST | ADP-GLUCOSE PYROPHOSPHORYLASE | 5-AMINOLEVULINIC ACID SYNTHESIS | PLANT SCIENCES | Chloroplasts - enzymology | Arabidopsis - enzymology | Thioredoxin-Disulfide Reductase - genetics | Seedlings - genetics | Seedlings - enzymology | Arabidopsis Proteins - metabolism | Protoporphyrins - genetics | Thioredoxins - genetics | Thioredoxin-Disulfide Reductase - metabolism | Light | Gene Expression Regulation, Plant | Plastids - genetics | Plastids - metabolism | Thioredoxins - metabolism | NADP - metabolism | Plant Leaves - enzymology | Chloroplasts - genetics | Thioredoxin-Disulfide Reductase - chemistry | Arabidopsis Proteins - genetics | Oxidation-Reduction | Protoporphyrins - metabolism | Tetrapyrroles - metabolism | Chloroplasts - metabolism | Arabidopsis - metabolism | Peroxiredoxins | Arabidopsis - genetics | Plastids - enzymology | Methyltransferases | Plant Leaves - genetics | Plant Leaves - metabolism | Tetrapyrroles - genetics | NADP - genetics | Seedlings - metabolism | Arabidopsis | Pyrrole | Cellular control mechanisms | Physiological aspects | Research | Properties | Observations | Index Medicus | Biochemistry and Metabolism
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2014, Volume 124, Issue 10, pp. 4294 - 4304
Journal Article
Cell death & disease, ISSN 2041-4889, 06/2017, Volume 8, Issue 6, pp. e2841 - e2841
Cytoprotective gene heme oxygenase 1 (HO-1) could be induced by nuclear factor E2-related factor 2 (Nrf2) nuclear translocation. The purpose of this study was... 
LIVER ISCHEMIA/REPERFUSION INJURY | OXIDATIVE STRESS | REACTIVE OXYGEN | NRF2 | GENE | BRG1 | HEME OXYGENASE-1 | CHROMATIN-REMODELING COMPLEXES | RESPONSE ELEMENT PATHWAY | EXPRESSION | CELL BIOLOGY | Chromatin - metabolism | Heme Oxygenase-1 - metabolism | Liver - pathology | Luciferases - metabolism | Protoporphyrins - pharmacology | Hepatocytes - pathology | Hepatocytes - metabolism | NAD(P)H Dehydrogenase (Quinone) - genetics | Luciferases - genetics | Heme Oxygenase-1 - genetics | Adenoviridae - genetics | NF-E2-Related Factor 2 - genetics | Membrane Proteins - metabolism | Nuclear Proteins - genetics | DNA Helicases - genetics | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | Genes, Reporter | Chromatin - chemistry | Cell Line | Promoter Regions, Genetic | Genetic Vectors - chemistry | Reperfusion Injury - pathology | Signal Transduction | Membrane Proteins - genetics | Liver - metabolism | Gene Expression Regulation | Genetic Vectors - metabolism | Mice, Transgenic | Nuclear Proteins - metabolism | Transcription Factors - genetics | Heme Oxygenase-1 - antagonists & inhibitors | Protein Transport | Transcription Factors - metabolism | DNA Helicases - metabolism | Animals | Membrane Proteins - antagonists & inhibitors | Active Transport, Cell Nucleus - drug effects | NF-E2-Related Factor 2 - metabolism | NAD(P)H Dehydrogenase (Quinone) - metabolism | Mice | Adenoviridae - metabolism | BRG1 protein | Immunoprecipitation | Liver diseases | Liver | Heme oxygenase (decyclizing) | Regulatory sequences | Gene expression | Nuclear transport | Chromatin remodeling | Oxygenase | Transfection | Reperfusion | Ischemia | Hepatocytes | Cellular biology | Rodents | Heme | Hypoxia | Brahma-related gene | NRF2 protein | Index Medicus | Original
Journal Article
The Plant Cell, ISSN 1040-4651, 11/2011, Volume 23, Issue 11, pp. 3992 - 4012
Journal Article
Cell, ISSN 0092-8674, 07/2014, Volume 158, Issue 1, pp. 25 - 40
Journal Article
The Plant Cell, ISSN 1040-4651, 11/2009, Volume 21, Issue 11, pp. 3473 - 3492
We hypothesized that chloroplast energy imbalance sensed through alterations in the redox state of the photosynthetic electron transport chain, measured as... 
Cotyledons | Phenotypes | Chloroplasts | Greening | Photons | Plants | Irradiance | Chlorophylls | Seedlings | Plant cells | ALTERNATIVE OXIDASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLASTOQUINONE POOL | CHLORELLA-VULGARIS | PLANT SCIENCES | CELL BIOLOGY | ENERGY-BALANCE | HARVESTING COMPLEX-II | GENE-EXPRESSION | PHOTOSYSTEM-II | PLASTID TERMINAL OXIDASE | MG-PROTOPORPHYRIN IX | CHLOROPLAST BIOGENESIS | ATP-Dependent Proteases - genetics | Temperature | Arabidopsis - growth & development | Mitochondrial Proteins | Genetic Variation - physiology | Metalloproteases - metabolism | Arabidopsis Proteins - metabolism | Mutation - physiology | Mitochondria - genetics | Light | Photosynthesis - physiology | Thylakoids - genetics | Membrane Proteins - metabolism | Energy Metabolism - genetics | Chloroplasts - genetics | Arabidopsis Proteins - genetics | Oxidation-Reduction | Oxidoreductases - metabolism | Membrane Proteins - genetics | Oxidoreductases - genetics | Gene Expression Regulation, Plant - genetics | Metalloproteases - genetics | Electron Transport Chain Complex Proteins - genetics | Mitochondria - metabolism | Cotyledon - genetics | Cotyledon - metabolism | Chloroplasts - metabolism | Thylakoids - metabolism | Arabidopsis - metabolism | Arabidopsis - genetics | Phenotype | Plant Leaves - genetics | Plant Leaves - metabolism | Plant Leaves - growth & development | Electron Transport Chain Complex Proteins - metabolism | Cotyledon - growth & development | Plant Proteins | Photic Stimulation | ATP-Dependent Proteases - metabolism | Arabidopsis thaliana | Physiological aspects | Leaves | Genetic aspects | Variegation | Research | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, pp. e50082 - e50082
Accumulation of protoporphyrin IX (PpIX) in malignant cells is the basis of 5-aminolevulinic acid (ALA)-mediated photodynamic therapy. We studied the... 
MYRISTOYLATION | BLADDER-CANCER | APOPTOSIS | MULTIDISCIPLINARY SCIENCES | GROWTH | TRAFFICKING | PHOTODYNAMIC DIAGNOSIS | HL-60 CELLS | MECHANISMS | PORPHYRIN HOMEOSTASIS | EXPRESSION | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Aminolevulinic Acid - toxicity | Humans | Endoplasmic Reticulum - metabolism | Neoplasm Proteins - metabolism | Recombinant Fusion Proteins - metabolism | Heterocyclic Compounds, 4 or More Rings | ATP-Binding Cassette Transporters - genetics | Biological Transport | Aminolevulinic Acid - metabolism | U937 Cells | HEK293 Cells | ATP-Binding Cassette Transporters - metabolism | Doxorubicin - metabolism | Neoplasm Proteins - genetics | Gene Expression | Peptide Transporter 1 | Aminolevulinic Acid - pharmacology | Protoporphyrins - metabolism | Glycosylation | Mitochondria - metabolism | Adenosine - pharmacology | Diketopiperazines | Symporters - metabolism | Protein Transport | Ferrochelatase - metabolism | Adenosine - analogs & derivatives | Cell Line, Tumor | Recombinant Fusion Proteins - genetics | Golgi Apparatus - metabolism | Proteins | Anthracyclines | Photochemotherapy | Cancer | Cytochrome | Microscopic analysis | Proteinase | Confocal | Aminolevulinic acid | Cytosol | Experiments | Doxorubicin | Urology | Accumulation | Mitochondria | Polysaccharides | Protoporphyrin | Localization | N-glycosidase | Pharmaceutical sciences | Polyclonal antibodies | University graduates | Medical research | Fractionation | Photodynamic therapy | Ferrochelatase | Cloning | Endoglycosidase H | Histology | Breast cancer | N-glycans | Tumor cell lines | Dentistry | Organelles | Exports | Golgi apparatus | Medicine | Endopeptidase K | Acids | Cellular biology | Protoporphyrin IX | Endoplasmic reticulum | Transporter | ABC transporter | Apoptosis | Index Medicus
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 8/2016, Volume 53, Issue 6, pp. 3586 - 3595
3-Hydroxy-3-methylglutaric aciduria (HMGA) is an inherited metabolic disorder caused by 3-hydroxy-3-methylglutaryl-CoA lyase deficiency. It is biochemically... 
Neurology | Oxidative stress | Neurosciences | Biomedicine | Astrocytes | Cytokine production | Neurobiology | ERK pathway | 3-Hydroxy-3-methylglutaric aciduria | Proinflammatory response | Cell Biology | GLIOMA-CELLS | RAT | GLIAL-CELLS | INTERLEUKIN-6 | NEUROSCIENCES | CEREBRAL-CORTEX | DAMAGE | HYPOGLYCEMIA | CENTRAL-NERVOUS-SYSTEM | BRAIN | Amino Acid Metabolism, Inborn Errors - complications | Inflammation - pathology | Reactive Oxygen Species - metabolism | Rats, Wistar | Antioxidants - metabolism | Astrocytes - pathology | Cerebral Cortex - pathology | Protoporphyrins - pharmacology | Male | NF-kappa B - metabolism | Meglutol - metabolism | Gliosis - pathology | Inflammation - complications | Amino Acid Metabolism, Inborn Errors - metabolism | Inflammation - metabolism | Flavonoids - pharmacology | Amino Acid Metabolism, Inborn Errors - pathology | Heme Oxygenase (Decyclizing) - antagonists & inhibitors | Heme Oxygenase (Decyclizing) - metabolism | Astrocytes - drug effects | Acetyl-CoA C-Acetyltransferase - deficiency | Cytokines - metabolism | Gliosis - metabolism | Cells, Cultured | Mitochondria - metabolism | Mitochondria - drug effects | Cell Shape - drug effects | Animals | MAP Kinase Signaling System - drug effects | Meglutol - analogs & derivatives | Metabolome - drug effects | Acetyl-CoA C-Acetyltransferase - metabolism | Astrocytes - metabolism | Brain | Chromosomal proteins | Metabolites | Cytokines | Seizures (Medicine) | Injuries | Organic acids | Metabolic disorders | Index Medicus
Journal Article