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Nature, ISSN 0028-0836, 01/2016, Volume 529, Issue 7584, pp. 105 - 109
Plasmodium falciparum antigens expressed on the surface of infected erythrocytes are important targets of naturally acquired immunity against malaria, but... 
LIFE-CYCLE | GENE | V(D)J RECOMBINASE | PLASMODIUM-FALCIPARUM | MULTIDISCIPLINARY SCIENCES | SURFACE | LYMPHOMA | TARGETS | DELETIONS | TRANSPOSITION | GENOME | Antibody Specificity | Clone Cells - cytology | Receptors, Immunologic - chemistry | Antigens, Protozoan - immunology | Epitopes, B-Lymphocyte - chemistry | Humans | DNA Transposable Elements - immunology | Molecular Sequence Data | Antibodies, Monoclonal - therapeutic use | Epitopes, B-Lymphocyte - immunology | Plasmodium falciparum - immunology | Malaria Vaccines - chemistry | Clone Cells - immunology | DNA Transposable Elements - genetics | Malaria Vaccines - immunology | Protozoan Proteins - chemistry | Conserved Sequence - immunology | Receptors, Immunologic - immunology | Antigenic Variation - immunology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Erythrocytes - immunology | Amino Acid Sequence | B-Lymphocytes - cytology | Collagen - immunology | Malaria - immunology | Membrane Proteins - immunology | Protein Structure, Tertiary - genetics | Kenya | Mutagenesis, Insertional - genetics | Antibodies, Monoclonal - genetics | Collagen - metabolism | B-Lymphocytes - immunology | Membrane Proteins - chemistry | Erythrocytes - metabolism | Malaria - parasitology | Erythrocytes - parasitology | Receptors, Immunologic - genetics | Protozoan Proteins - immunology | Receptors, Immunologic - metabolism | Antigen-antibody reactions | Host-parasite relationships | Genetic aspects | Malaria | Observations | Genetic variation | Antigens | Immunoglobulins | Genes | Erythrocytes | Monoclonal antibodies | Mutation | Chromosomes
Journal Article
Science, ISSN 0036-8075, 6/2005, Volume 308, Issue 5728, pp. 1626 - 1629
Mammalian Toll-like receptors (TLRs) play an important role in the innate recognition of pathogens by dendritic cells (DCs). Although TLRs are clearly involved... 
Molecules | Pathogens | Cytokines | Dendritic cells | Profilins | Ligands | Reports | Mice | Infections | Parasites | Parasite hosts | IMMUNITY | TOLL-LIKE RECEPTOR-5 | STRANDED-RNA | TOXOPLASMA-GONDII INFECTION | RECOGNITION | GENE | MULTIDISCIPLINARY SCIENCES | RESISTANCE | IL-12 | PARASITE | CUTTING EDGE | Toxoplasma - immunology | Membrane Glycoproteins - metabolism | Dendritic Cells - immunology | Molecular Sequence Data | Genes, Protozoan | NF-kappa B - metabolism | Interleukin-12 - blood | Toll-Like Receptors | Protozoan Proteins - metabolism | Transfection | Antigens, Differentiation - metabolism | Protozoan Proteins - chemistry | Microfilament Proteins - metabolism | Contractile Proteins - metabolism | Interleukin-12 - biosynthesis | Amino Acid Sequence | Microfilament Proteins - chemistry | Microfilament Proteins - isolation & purification | Signal Transduction | Mice, Inbred C57BL | Receptors, Cell Surface - metabolism | Contractile Proteins - chemistry | Myeloid Differentiation Factor 88 | Immunity, Innate | Amino Acid Motifs | Adaptor Proteins, Signal Transducing | Animals | Toxoplasma - genetics | Recombinant Proteins - immunology | Protozoan Proteins - isolation & purification | Microfilament Proteins - immunology | Toxoplasmosis, Animal - immunology | Contractile Proteins - immunology | Contractile Proteins - isolation & purification | Antigens, Differentiation - genetics | Receptors, Immunologic - genetics | Protozoan Proteins - immunology | Receptors, Immunologic - metabolism | Protozoa | Research | Analysis | Proteins | Cellular biology | Protozoan enzymes
Journal Article
Immunity, ISSN 1074-7613, 12/2017, Volume 47, Issue 6, pp. 1197 - 1209.e10
Antibodies against the NANP repeat of circumsporozoite protein (CSP), the major surface antigen of ( ) sporozoites, can protect from malaria in animal models... 
circumsporozoite protein | Plasmodium falciparum | natural infection | affinity maturation | protective antibodies | malaria | memory B cells | epitope specificity | human | X-ray structures | SYSTEM | RESPONSES | IMMUNITY | TRANSMISSION | MEMORY B-CELLS | HUMAN MALARIA | STAGE | PLASMODIUM-FALCIPARUM SPOROZOITES | CIRCUMSPOROZOITE PROTEIN | IMMUNOLOGY | MONOCLONAL-ANTIBODIES | Plasmodium berghei - immunology | Immunoglobulin Heavy Chains - biosynthesis | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Humans | B-Lymphocytes - parasitology | Immunoglobulin Heavy Chains - chemistry | Crystallography, X-Ray | Male | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Sporozoites - immunology | Epitopes - immunology | Sporozoites - chemistry | Immunity, Humoral | Female | Protozoan Proteins - chemistry | Antigens, Protozoan - genetics | Protein Interaction Domains and Motifs | Immunoglobulin Heavy Chains - immunology | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Gene Expression | Antigens, Protozoan - chemistry | Antibodies, Protozoan - immunology | Malaria - immunology | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Antibodies, Protozoan - chemistry | Antibodies, Protozoan - biosynthesis | Malaria - prevention & control | Malaria, Falciparum - parasitology | Animals | B-Lymphocytes - immunology | Protein Conformation, beta-Strand | Malaria - parasitology | Malaria, Falciparum - immunology | Protein Binding | Immunologic Memory | Epitopes - chemistry | Mice | Protozoan Proteins - immunology | Viral antibodies | Wildlife conservation | Malaria | Analysis | Children's hospitals | Malaria vaccine | Antibodies | Development and progression | B cells | Health aspects | Antigenic determinants | Vector-borne diseases | Animal models | Immunological memory | Immunoglobulins | Complementarity | Molecular structure | Vaccines | Epitopes | Parasites | Aquatic insects | Immunity | Disease transmission | Lymphocytes B | Coding | Sporozoites | Monoclonal antibodies | Affinity | Immunity (humoral) | Human behavior | Complementarity-determining region 3 | Binding sites | Circumsporozoite protein
Journal Article
Molecular and Cellular Proteomics, ISSN 1535-9476, 12/2013, Volume 12, Issue 12, pp. 3976 - 3986
Malaria, an infectious disease caused by parasites of the Plasmodium genus, is one of the world's major public health concerns causing up to a million deaths... 
HIGH-LEVEL | ENHANCED EXPRESSION | RTS,S/AS01 MALARIA VACCINE | ESCHERICHIA-COLI | BIOCHEMICAL RESEARCH METHODS | PARASITE PLASMODIUM-FALCIPARUM | MULTIGENE FAMILY | PHASE-3 TRIAL | INHIBITORY ANTIBODIES | HETEROLOGOUS EXPRESSION | ERYTHROCYTE INVASION | Proteome - genetics | Antigens, Protozoan - immunology | Immune Sera - chemistry | Humans | Merozoite Surface Protein 1 - genetics | Peptide Library | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Merozoite Surface Protein 1 - metabolism | Antigens, Protozoan - metabolism | Protozoan Proteins - metabolism | Plasmodium falciparum - genetics | Proteome - immunology | Cloning, Molecular | HEK293 Cells | Antigens, Surface - metabolism | Plasmodium falciparum - metabolism | Antigens, Protozoan - genetics | Membrane Proteins - metabolism | Carrier Proteins - immunology | Merozoites - metabolism | Merozoites - immunology | Recombinant Proteins - metabolism | Gene Expression | Membrane Proteins - genetics | Molecular Sequence Annotation | Antigens, Surface - genetics | Sialic Acids - metabolism | Membrane Proteins - immunology | Recombinant Proteins - genetics | Carrier Proteins - genetics | Carrier Proteins - metabolism | Recombinant Proteins - immunology | Merozoite Surface Protein 1 - immunology | Protein Binding | Erythrocytes - parasitology | Merozoites - chemistry | Antigens, Surface - immunology | Proteome - metabolism | Protozoan Proteins - immunology | Technological Innovation and Resources
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2010, Volume 185, Issue 9, pp. 5011 - 5022
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2013, Volume 210, Issue 10, pp. 2071 - 2086
Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular protozoan parasite that resides inside a parasitophorous vacuole. During... 
MEDICINE, RESEARCH & EXPERIMENTAL | GONDII INFECTION | DENDRITIC CELLS | DOCKING INTERACTIONS | IFN-GAMMA | GENE-EXPRESSION | RESISTANCE | P38-ALPHA | IMMUNOLOGY | KINASE ACTIVATION | BINDING | AUTOPHOSPHORYLATION | Toxoplasma - immunology | Phosphorylation | Toxoplasmosis - immunology | Humans | Protein Multimerization | Molecular Sequence Data | Gene Expression Profiling | Protozoan Proteins - genetics | Cell Nucleus - metabolism | Protozoan Proteins - metabolism | Toxoplasmosis - metabolism | Gene Deletion | Early Growth Response Protein 1 - genetics | Female | Protozoan Proteins - chemistry | Protein Interaction Domains and Motifs | p38 Mitogen-Activated Protein Kinases - metabolism | Gene Order | Macrophages - immunology | Amino Acid Sequence | Cell Line | Chemokines - biosynthesis | Proto-Oncogene Proteins c-fos - metabolism | Models, Molecular | Inflammation - immunology | Amino Acid Motifs | Protein Transport | Macrophages - metabolism | Sequence Alignment | Animals | Toxoplasma - genetics | Inflammation - genetics | Protein Binding | Protein Conformation | Proto-Oncogene Proteins c-fos - genetics | Mice | Enzyme Activation | p38 Mitogen-Activated Protein Kinases - chemistry | Early Growth Response Protein 1 - metabolism | Protozoan Proteins - immunology | Cluster Analysis | Life Sciences | Biochemistry, Molecular Biology | Genomics
Journal Article
Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 580 - 590
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, p. e106241
Background: Fifteen volunteers were immunized with three doses of plasmid DNA encoding P. falciparum circumsporozoite protein (CSP) and apical membrane... 
APICAL MEMBRANE ANTIGEN-1 | RESPONSES | IMMUNOGENICITY | PROTEIN | PROTECTION | LIVER STAGES | SAFETY | MULTIDISCIPLINARY SCIENCES | VACCINE | CANDIDATE | CD8(+) T-CELLS | Antigens, Protozoan - immunology | DNA - immunology | Humans | Malaria, Falciparum - pathology | DNA - administration & dosage | Membrane Proteins - immunology | Plasmodium falciparum - immunology | Epitopes - immunology | Membrane Proteins - administration & dosage | Malaria, Falciparum - parasitology | Interleukin-2 - immunology | Malaria Vaccines - administration & dosage | Interferon-gamma - immunology | Antigens, Protozoan - administration & dosage | Malaria Vaccines - immunology | Malaria, Falciparum - immunology | Tumor Necrosis Factor-alpha - immunology | Plasmodium falciparum - pathogenicity | Adult | Immunologic Memory | Protozoan Proteins - administration & dosage | Adenoviridae - immunology | CD8-Positive T-Lymphocytes - immunology | Protozoan Proteins - immunology | Infection | Plasmodium falciparum | Immunization | Malaria | Adenoviruses | DNA | Interferon | T cells | Health aspects | Antigenic determinants | CD8 antigen | Liver | Effector cells | Lymphocytes T | Infections | Vaccines | Immunity | Proteins | Immunology | Interleukin 2 | Lymphocytes | Plasmid DNA | Volunteers | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Circumsporozoite protein | Vector-borne diseases | Antigens | Medical research | Immunological memory | Memory cells | Priming | Epitopes | Tumor necrosis factor-α | Vectors (Biology) | Membrane proteins | Plasmids | γ-Interferon | Comparative analysis | Deoxyribonucleic acid
Journal Article
Nature Communications, ISSN 2041-1723, 11/2013, Volume 4, Issue 1, p. 2836
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2013, Volume 9, Issue 12, pp. 1 - 17
Journal Article