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Science, ISSN 0036-8075, 6/2005, Volume 308, Issue 5728, pp. 1626 - 1629
Mammalian Toll-like receptors (TLRs) play an important role in the innate recognition of pathogens by dendritic cells (DCs). Although TLRs are clearly involved... 
Molecules | Pathogens | Cytokines | Dendritic cells | Profilins | Ligands | Reports | Mice | Infections | Parasites | Parasite hosts | IMMUNITY | TOLL-LIKE RECEPTOR-5 | STRANDED-RNA | TOXOPLASMA-GONDII INFECTION | RECOGNITION | GENE | MULTIDISCIPLINARY SCIENCES | RESISTANCE | IL-12 | PARASITE | CUTTING EDGE | Toxoplasma - immunology | Membrane Glycoproteins - metabolism | Dendritic Cells - immunology | Molecular Sequence Data | Genes, Protozoan | NF-kappa B - metabolism | Interleukin-12 - blood | Toll-Like Receptors | Protozoan Proteins - metabolism | Transfection | Antigens, Differentiation - metabolism | Protozoan Proteins - chemistry | Microfilament Proteins - metabolism | Contractile Proteins - metabolism | Interleukin-12 - biosynthesis | Amino Acid Sequence | Microfilament Proteins - chemistry | Microfilament Proteins - isolation & purification | Signal Transduction | Mice, Inbred C57BL | Receptors, Cell Surface - metabolism | Contractile Proteins - chemistry | Myeloid Differentiation Factor 88 | Immunity, Innate | Amino Acid Motifs | Adaptor Proteins, Signal Transducing | Animals | Toxoplasma - genetics | Recombinant Proteins - immunology | Protozoan Proteins - isolation & purification | Microfilament Proteins - immunology | Toxoplasmosis, Animal - immunology | Contractile Proteins - immunology | Contractile Proteins - isolation & purification | Antigens, Differentiation - genetics | Receptors, Immunologic - genetics | Protozoan Proteins - immunology | Receptors, Immunologic - metabolism | Protozoa | Research | Analysis | Proteins | Cellular biology | Protozoan enzymes
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0148517
Plasmodium falciparum, the human pathogen responsible for the most dangerous malaria infection, survives and develops in mature erythrocytes through the export... 
HSP70 CHAPERONES | J PROTEINS | DNAJ | YEAST HSP40 | PLASMODIUM-FALCIPARUM | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | MOLECULAR CHAPERONE | DIMERIZATION | PARASITE | Protein Aggregates | Molecular Chaperones - metabolism | Humans | Molecular Chaperones - chemistry | Recombinant Proteins | Protozoan Proteins - genetics | Thiosulfate Sulfurtransferase - metabolism | Protozoan Proteins - metabolism | Plasmodium falciparum - genetics | Plasmodium falciparum - metabolism | Protozoan Proteins - chemistry | HSP70 Heat-Shock Proteins - chemistry | HSP40 Heat-Shock Proteins - chemistry | HSP40 Heat-Shock Proteins - metabolism | HSP40 Heat-Shock Proteins - genetics | HSP40 Heat-Shock Proteins - isolation & purification | Molecular Chaperones - genetics | Adenosine Triphosphatases - metabolism | HSP70 Heat-Shock Proteins - genetics | HSP70 Heat-Shock Proteins - metabolism | Malaria, Falciparum - parasitology | Protozoan Proteins - isolation & purification | Protein Binding | HSP70 Heat-Shock Proteins - isolation & purification | Kinetics | Molecular Chaperones - isolation & purification | Plasmodium falciparum | Malaria | Heat shock proteins | Physiological aspects | Causes of | Genetic aspects | Research | Biotechnology | Yeast | Trafficking | Erythrocytes | Biochemistry | Chaperones | Parasites | Drug resistance | Cytosol | Proteins | Red blood cells | E coli | Protein folding | Protein transport | Recombinant | Vector-borne diseases | Hsp70 protein | Hsp40 protein | Exports | Rhodanese | Human behavior | Adenosine triphosphatase | Heat shock
Journal Article
Biotechnology and Bioengineering, ISSN 0006-3592, 07/2015, Volume 112, Issue 7, pp. 1297 - 1305
ABSTRACT Malaria is a vector‐borne disease affecting more than two million people and accounting for more than 600,000 deaths each year, especially in... 
agroinfiltration | Plasmodium falciparum | downstream processing | plant‐made vaccine | host cell protein removal | Plant-made vaccine | Agroinfiltration | Host cell protein removal | Downstream processing | HIGH-LEVEL | ANTIBODIES | RECOMBINANT PFS25 | STAGE | INFECTIVITY | ANTIGENS | INDUCTION | CHALLENGES | plant-made vaccine | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PLASMODIUM-FALCIPARUM | IMMUNE-RESPONSES | Recombinant Fusion Proteins - immunology | Recombinant Fusion Proteins - isolation & purification | Antigens, Protozoan - immunology | Tobacco - metabolism | Hot Temperature | Protozoan Proteins - genetics | Recombinant Fusion Proteins - metabolism | Antigens, Protozoan - metabolism | Animals | Plants, Genetically Modified - metabolism | Protozoan Proteins - metabolism | Vaccination - methods | Protozoan Proteins - isolation & purification | Tobacco - genetics | Malaria Vaccines - immunology | Recombinant Fusion Proteins - genetics | Antigens, Protozoan - isolation & purification | Antigens, Protozoan - genetics | Mice | Malaria Vaccines - isolation & purification | Fractional Precipitation | Malaria Vaccines - metabolism | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Developing countries | Disease transmission | Vaccines | Precipitation (Meteorology) | Malaria | Malaria vaccine | Proteins | Tobacco | Purification | Parasites | Recombinant
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, pp. e0129445 - e0129445
Journal Article
Journal Article
Journal Article
Protein Expression and Purification, ISSN 1046-5928, 12/2018, Volume 152, pp. 122 - 130
Plants as a platform for recombinant protein expression are now economically comparable to well-established systems, such as microbes and mammalian cells,... 
Plant-derived biopharmaceuticals | Liquid handling station | Design of experiments | Downstream processing | Blanching | ANTIBODIES | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | I CLINICAL-TRIAL | TRANSGENIC TOBACCO PLANTS | HYDROPHOBIC INTERACTION CHROMATOGRAPHY | EXTRACTION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PLASMODIUM-FALCIPARUM | PURIFICATION | EXPRESSION | DEPTH FILTERS | Ultrafiltration - methods | Malaria Vaccines - biosynthesis | Recombinant Proteins - biosynthesis | Protozoan Proteins - genetics | Recombinant Proteins - isolation & purification | Plant Proteins - chemistry | Plants, Genetically Modified | Cloning, Molecular | Protein Denaturation | Antibodies, Monoclonal - chemistry | Chromatography, Affinity - methods | Plant Proteins - isolation & purification | Sepharose - analogs & derivatives | Gene Expression | Genetic Vectors - chemistry | Tobacco - metabolism | Genetic Vectors - metabolism | Factor Analysis, Statistical | Recombinant Proteins - genetics | Hot Temperature | Protozoan Proteins - biosynthesis | Antibodies, Protozoan - chemistry | Plant Leaves - genetics | Plant Leaves - metabolism | Protozoan Proteins - isolation & purification | Tobacco - genetics | Protein Binding | Tobacco - chemistry | Antibodies, Monoclonal - metabolism | Malaria Vaccines - isolation & purification | Antibodies, Protozoan - metabolism | Malaria Vaccines - genetics
Journal Article
Protein Expression and Purification, ISSN 1046-5928, 08/2017, Volume 136, pp. 52 - 57
is dependent on interaction with the Duffy antigen receptor for chemokines (DARC) for invasion of human erythrocytes. The Duffy binding protein (PvDBP)... 
Plasmodium vivax | Malaria vaccines | Recombinant vaccines | Protein refolding | Duffy binding protein | Fed-batch fermentation | Host cell invasion | Adjuvants | Vaccine formulation | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | Immunogenicity, Vaccine | Antigens, Protozoan - immunology | Humans | Antigens, Protozoan - biosynthesis | Plasmodium vivax - genetics | Malaria Vaccines - biosynthesis | Recombinant Proteins - biosynthesis | Protozoan Proteins - genetics | Recombinant Proteins - isolation & purification | Malaria Vaccines - immunology | Protein Domains | Antigens, Protozoan - isolation & purification | Antigens, Protozoan - genetics | Receptors, Cell Surface - biosynthesis | Receptors, Cell Surface - isolation & purification | Plasmodium vivax - immunology | Protozoan Proteins - biosynthesis | Receptors, Cell Surface - immunology | Animals | Recombinant Proteins - immunology | Protozoan Proteins - isolation & purification | Mice | Mice, Inbred BALB C | Malaria Vaccines - isolation & purification | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Receptors, Cell Surface - genetics | Antigens | Cysteine | Malaria vaccine | Escherichia coli | Lipids | Vaccines | Fermentation | Chromatography | Analysis | Genetically modified organisms | Genetic engineering | Enzyme-linked immunosorbent assay | Protein binding
Journal Article