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American Journal of Physiology - Renal Physiology, ISSN 1931-857X, 04/2009, Volume 296, Issue 4, pp. 902 - 911
Human glomerulonephritis (GN) is characterized by sustained proteinuria, sodium retention, hypertension, and edema formation. Increasing quantities of filtered... 
Proximal tubule | Proteolytic cleavage | NaPi-lla | Collecting duct | ENaC | Megalin | AQP1 | PHYSIOLOGY | RAT-KIDNEY | megalin | EPITHELIAL SODIUM-CHANNEL | proteolytic cleavage | EXPERIMENTAL NEPHROTIC SYNDROME | BLOOD-PRESSURE | NA+-K+-ATPASE | RENAL ENAC SUBUNITS | collecting duct | LIPID RAFTS | UROLOGY & NEPHROLOGY | NaPi-IIa | proximal tubule | GAMMA-SUBUNIT | THICK ASCENDING LIMB | Blood Pressure | Epithelial Sodium Channels - metabolism | Sodium - metabolism | Glomerulonephritis - metabolism | Aquaporin 1 - metabolism | Sodium-Hydrogen Exchangers - metabolism | Sodium-Phosphate Cotransporter Proteins, Type IIa - metabolism | Endocytosis | Cyclooxygenase 2 - blood | Sodium - urine | Female | Membrane Transport Proteins - metabolism | Low Density Lipoprotein Receptor-Related Protein-2 - genetics | Glomerulonephritis - physiopathology | Kidney Tubules - metabolism | Disease Models, Animal | Kidney Tubules - immunology | Low Density Lipoprotein Receptor-Related Protein-2 - deficiency | Vitamin D-Binding Protein - urine | Autoantibodies | Proteinuria - immunology | Aldosterone - blood | Proteinuria - metabolism | Glomerulonephritis - immunology | Renin - blood | Sodium - blood | Mice, Knockout | Protein Transport | Proteinuria - physiopathology | Aquaporin 2 - metabolism | Animals | Kidney Tubules - enzymology | Mice | Sodium-Hydrogen Exchanger 3
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 01/2017, Volume 28, Issue 1, pp. 230 - 241
Renal proximal tubular cells constantly recycle nutrients to ensure minimal loss of vital substrates into the urine. Although most of the transport mechanisms... 
RAPAMYCIN | COMPLEX | PHOSPHORYLATION | DISEASE | COTRANSPORTER | UROLOGY & NEPHROLOGY | ANGIOTENSIN-II | KIDNEY | SIROLIMUS | TRANSPLANTATION | NEPHRON | albuminuria | epithelial transport | proteomics | mTOR | endocytosis | proximal tubule | Basic Research
Journal Article
Journal Article
Kidney International, ISSN 0085-2538, 05/2016, Volume 89, Issue 5, pp. 1075 - 1089
Hepatocyte nuclear factor 1α (HNF1α) is a transcription factor expressed in the liver, pancreas, and proximal tubule of the kidney. Mutations of HNF1α cause an... 
transcription regulation | endocytosis | proximal tubule | diabetes insipidus | URINARY-EXCRETION | RETINOL-BINDING-PROTEIN | DIABETIC-PATIENTS | CLC-5 | RECEPTOR-MEDIATED ENDOCYTOSIS | UROLOGY & NEPHROLOGY | MEGALIN | CHLORIDE CHANNEL | DENTS-DISEASE | KIDNEY | TRANSCRIPTION FACTOR | Hepatocyte Nuclear Factor 1-alpha - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | Diabetes Mellitus, Type 2 - metabolism | Hepatocyte Nuclear Factor 1-alpha - metabolism | Case-Control Studies | Young Adult | Endocytosis | Diabetic Nephropathies - physiopathology | Transfection | Hepatocyte Nuclear Factor 1-alpha - deficiency | Adult | Female | Low Density Lipoprotein Receptor-Related Protein-2 - genetics | Binding Sites | Kidney Tubules, Proximal - physiopathology | Promoter Regions, Genetic | Genetic Predisposition to Disease | Signal Transduction | Diabetic Nephropathies - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Proteinuria - metabolism | Receptors, Cell Surface - metabolism | Diabetic Nephropathies - genetics | Low Density Lipoprotein Receptor-Related Protein-2 - metabolism | Proteinuria - genetics | Mice, Knockout | Proteinuria - physiopathology | Phenotype | Animals | Diabetes Mellitus, Type 2 - physiopathology | Adolescent | Kidney Tubules, Proximal - metabolism | Aged | Mutation | Receptors, Cell Surface - genetics
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 06/2012, Volume 684, Issue 1-3, pp. 146 - 153
Journal Article
Journal Article