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1. Full Text pH-Mediated Potentiation of Aminoglycosides Kills Bacterial Persisters and Eradicates In Vivo Biofilms
by David Lebeaux and Ashwini Chauhan and Sylvie Létoffé and Frédéric Fischer and Hilde de Reuse and Christophe Beloin and Jean-Marc Ghigo
The Journal of infectious diseases, ISSN 0022-1899, 11/2014, Volume 210, Issue 9, pp. 1357 - 1366
Biofilms | Antibiotics | Escherichia coli | Bacteria | Aminoglycosides | Pseudomonas aeruginosa | Infections | Basic amino acids | Staphylococcus aureus | aminoglycoside | persister | catheter-related infections | biofilm | proton motive force | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Escherichia coli Infections - prevention & control | Central Venous Catheters - microbiology | Escherichia coli - drug effects | Gentamicins - administration & dosage | Catheter-Related Infections - prevention & control | Pseudomonas Infections - prevention & control | Arginine - administration & dosage | Gentamicins - pharmacology | Drug Therapy, Combination | Biofilms - drug effects | Escherichia coli Infections - drug therapy | Staphylococcal Infections - drug therapy | Pseudomonas Infections - drug therapy | Rats | Central Venous Catheters - adverse effects | Pseudomonas aeruginosa - drug effects | Catheter-Related Infections - drug therapy | Drug Synergism | Animals | Arginine - pharmacology | Staphylococcal Infections - prevention & control | Anti-Bacterial Agents - pharmacology | In Vitro Techniques | Staphylococcus aureus - drug effects | Hydrogen-Ion Concentration | Health aspects | Research | Index Medicus | Abridged Index Medicus | Biofilms/drug effects | Gentamicins/administration & dosage | Anti-Bacterial Agents/pharmacology | Staphylococcal Infections/drug therapy | Arginine/administration & dosage | Life Sciences | Escherichia coli Infections/drug therapy | Staphylococcus aureus/drug effects | Gentamicins/pharmacology | Catheter-Related Infections/prevention & control | Pseudomonas aeruginosa/drug effects | Staphylococcal Infections/prevention & control | Catheter-Related Infections/drug therapy | Central Venous Catheters/microbiology | Escherichia coli/drug effects | Bacteriology | Microbiology and Parasitology | Central Venous Catheters/adverse effects | Arginine/pharmacology | Pseudomonas Infections/prevention & control | Escherichia coli Infections/prevention & control | Pseudomonas Infections/drug therapy
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2. Full Text Species-specific activity of antibacterial drug combinations
by Brochado, Ana Rita and Telzerow, Anja and Bobonis, Jacob and Banzhaf, Manuel and Mateus, André and Selkrig, Joel and Huth, Emily and Bassler, Stefan and Zamarreño Beas, Jordi and Zietek, Matylda and Ng, Natalie and Foerster, Sunniva and Ezraty, Benjamin and Py, Béatrice and Barras, Frédéric and Savitski, Mikhail M and Bork, Peer and Göttig, Stephan and Typas, Athanasios
Nature (London), ISSN 0028-0836, 07/2018, Volume 559, Issue 7713, pp. 259 - 263
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Pharmaceutical research | Drug resistance in microorganisms | Research | Antibiosis | Drug interactions | Drugs | Larvae | Salmonella | Colistin | Clinical isolates | Infections | Phylogeny | Drug resistance | Experiments | Proteins | E coli | Food additives | Bacteria | Pseudomonas aeruginosa | Drug dosages | Species | Public health | Integrated approach | Bacterial infections | Antimicrobial agents | Gene expression | Antibiotics | Antimicrobial resistance | Vanillin | Drug additives | Index Medicus | Drug Synergism | Life Sciences | Microbiology and Parasitology | Species Specificity | Salmonella typhimurium/classification | Escherichia coli/drug effects | Anti-Bacterial Agents/pharmacology | Pseudomonas aeruginosa/drug effects | Pseudomonas aeruginosa/classification
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3. Full Text Quorum-Sensing Systems as Targets for Antivirulence Therapy
by Defoirdt, Tom
Trends in microbiology (Regular ed.), ISSN 0966-842X, 04/2018, Volume 26, Issue 4, pp. 313 - 328
quorum-sensing-interference | quorum-sensing inhibitor | Pseudomonas | quorum quenching | Vibrio | Xanthomonas | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virulence - drug effects | Xanthomonas - metabolism | Quorum Sensing - drug effects | Bacterial Infections - drug therapy | Quorum Sensing - physiology | Bacterial Physiological Phenomena - drug effects | Humans | Bacteria - drug effects | Pseudomonas - pathogenicity | Plants | Virulence Factors | Vibrio - metabolism | Xanthomonas - pathogenicity | Bacterial Infections - prevention & control | Animals | Pseudomonas - drug effects | Xanthomonas - drug effects | Vibrio - drug effects | Anti-Bacterial Agents - pharmacology | Bacteria - pathogenicity | Drug Resistance, Bacterial - drug effects | Vibrio - pathogenicity | Pseudomonas - metabolism | Pathogens | Chemical communication | Antibiotics | Virulence | Antibiotic resistance | Gram-negative bacteria | Drug resistance | Cell interactions | Detection | Molecular chains | Index Medicus
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4. Full Text In Vitro Activities of Dermaseptins K4S4 and K4K20S4 against Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa Planktonic Growth and Biofilm Formation
by Zairi, Amira and Ferrieres, Lionel and Latour-Lambert, Patricia and Beloin, Christophe and Tangy, Frederic and Ghigo, Jean-Marc and Hania, Khaled
Antimicrobial agents and chemotherapy, ISSN 0066-4804, 04/2014, Volume 58, Issue 4, pp. 2221 - 2228
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Infectious diseases | Bacterial diseases | Human bacterial diseases | Pharmacology. Drug treatments | Staphylococcal infections, streptococcal infections, pneumococcal infections | Biological and medical sciences | Medical sciences | Antibiotics. Antiinfectious agents. Antiparasitic agents | Biofilms - drug effects | Microbial Sensitivity Tests | Gram-Negative Bacteria - drug effects | Amphibian Proteins - pharmacology | Gram-Positive Bacteria - drug effects | Escherichia coli - drug effects | Humans | Antimicrobial Cationic Peptides - pharmacology | Anti-Bacterial Agents - pharmacology | HeLa Cells | Pseudomonas aeruginosa - drug effects | Staphylococcus aureus - drug effects | Index Medicus | Biofilms/drug effects | Amphibian Proteins/pharmacology | Gram-Negative Bacteria/drug effects | Anti-Bacterial Agents/pharmacology | Escherichia coli/drug effects | Bacteriology | Gram-Positive Bacteria/drug effects | Life Sciences | Microbiology and Parasitology | Antimicrobial Cationic Peptides/pharmacology | Staphylococcus aureus/drug effects | Pseudomonas aeruginosa/drug effects | Susceptibility
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5. Full Text Dietary Pectin-Derived Acidic Oligosaccharides Improve the Pulmonary Bacterial Clearance of Pseudomonas aeruginosa Lung Infection in Mice by Modulating Intestinal Microbiota and Immunity
by Henry Bernard and Jean-Luc Desseyn and Nana Bartke and Lennart Kleinjans and Bernd Stahl and Clara Beizer and Jan Knol and Frédéric Gottrand and Marie-Odile Husson
The Journal of infectious diseases, ISSN 0022-1899, 1/2015, Volume 211, Issue 1, pp. 156 - 165
PATHOGENESIS AND HOST RESPONSE | human-milk | cytokine production | butyrate | in-vitro | chain fatty-acids | galacto-oligosaccharides | t-cells | lactobacillus | virus-infection | cystic-fibrosis patients | intestinal microbiota | prebiotics | Th1 and M1 polarization | P. aeruginosa lung infection | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Intestines - drug effects | Lung Diseases - microbiology | GATA3 Transcription Factor - immunology | Pseudomonas aeruginosa - growth & development | Microbiota - drug effects | Male | T-Box Domain Proteins - immunology | Lung Diseases - drug therapy | Th1 Cells - immunology | Intestines - immunology | Leukocytes - immunology | Oligosaccharides - pharmacology | Leukocytes - microbiology | Tumor Necrosis Factor-alpha - immunology | Keratinocytes - microbiology | Macrophages - immunology | Macrophages - microbiology | Chemotactic Factors - immunology | Microbiota - immunology | Pseudomonas Infections - drug therapy | Pseudomonas aeruginosa - drug effects | Pseudomonas Infections - microbiology | Keratinocytes - immunology | Pectins - chemistry | Pseudomonas Infections - immunology | Lung Diseases - immunology | Interleukin-4 - immunology | Th1 Cells - microbiology | Animals | Intestines - microbiology | Interferon-gamma - immunology | Mice | Mice, Inbred BALB C | Interleukin-10 - immunology | Index Medicus | Abridged Index Medicus | Pseudomonas Infections/microbiology | Macrophages/microbiology | Oligosaccharides/pharmacology | Macrophages/immunology | Lung Diseases/immunology | Lung Diseases/microbiology | Interferon-gamma/immunology | Keratinocytes/microbiology | Microbiota/drug effects | Life Sciences | Leukocytes/microbiology | Pseudomonas Infections/immunology | Interleukin-10/immunology | Lung Diseases/drug therapy | T-Box Domain Proteins/immunology | Leukocytes/immunology | Pseudomonas aeruginosa/drug effects | Th1 Cells/microbiology | GATA3 Transcription Factor/immunology | Interleukin-4/immunology | Intestines/drug effects | Intestines/microbiology | Keratinocytes/immunology | Chemotactic Factors/immunology | Tumor Necrosis Factor-alpha/immunology | Microbiota/immunology | Pseudomonas aeruginosa/growth & development | Pectins/chemistry | Pseudomonas Infections/drug therapy | Th1 Cells/immunology | Intestines/immunology
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6. Full Text Clinical mechanism of the cystic fibrosis transmembrane conductance regulator potentiator ivacaftor in G551D-mediated cystic fibrosis
by Rowe, Steven M and Rowe, Steven M and Heltshe, Sonya L and Heltshe, Sonya L and Gonska, Tanja and Gonska, Tanj and Donaldson, Scott H and Donaldson, Scott H and Borowitz, Drucy and Borowitz, Druc and Gelfond, Daniel and Gelfond, Danie and Sagel, Scott D and Sagel, Scott D and Khan, Ume and Khan, Umer and Mayer-Hamblett, Nicole and Mayer-Hamblett, Nicol and Van Dalfsen, Jill M and Van Dalfsen, Jill M and Joseloff, Elizabeth and Joseloff, Elizabet and Ramsey, Bonnie W and Ramsey, Bonnie W and GOAL Investigators Cystic Fibrosis and GOAL Investigators of the Cystic Fibrosis Foundation Therapeutics Development Network
American journal of respiratory and critical care medicine, ISSN 1073-449X, 2014, Volume 190, Issue 2, pp. 175 - 184
Cystic fibrosis | Pseudomonas aeruginosa | Ivacaftor | CFTR modulator | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Sputum - microbiology | Lung - microbiology | Pseudomonas aeruginosa - isolation & purification | Follow-Up Studies | Forced Expiratory Volume - drug effects | Sweat - drug effects | Humans | Microbiota - drug effects | Respiratory System Agents - therapeutic use | Hospitalization - statistics & numerical data | Male | Aminophenols - therapeutic use | Quinolones - pharmacology | Aminophenols - pharmacology | Mucociliary Clearance - drug effects | Pseudomonas Infections - prevention & control | Young Adult | Hydrogen-Ion Concentration - drug effects | Quinolones - therapeutic use | Adult | Female | Lung - metabolism | Child | Biomarkers - metabolism | Respiratory System Agents - pharmacology | Cystic Fibrosis - metabolism | Cystic Fibrosis - microbiology | Pseudomonas Infections - complications | Pseudomonas Infections - diagnosis | Treatment Outcome | Lung - physiopathology | Genetic Markers | Sputum - metabolism | Cystic Fibrosis - genetics | Intestine, Small - drug effects | Lung - drug effects | Adolescent | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Intestine, Small - metabolism | Mutation | Cystic Fibrosis - drug therapy | Sweat - metabolism | Index Medicus | Abridged Index Medicus | ivacaftor | Original | cystic fibrosis
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7. Full Text Antimicrobial Efficacy of Riboflavin/UVA Combination (365 nm) In Vitro for Bacterial and Fungal Isolates: A Potential New Treatment for Infectious Keratitis
by Martins, Suy Anne R and Combs, Juan Castro and Noguera, Guillermo and Camacho, Walter and Wittmann, Priscila and Walther, Rhonda and Cano, Marisol and Dick, James and Behrens, Ashley
Investigative ophthalmology & visual science, ISSN 0146-0404, 08/2008, Volume 49, Issue 8, pp. 3402 - 3408
Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Eye and associated structures. Visual pathways and centers. Vision | Diseases of cornea, anterior segment and sclera | Biological and medical sciences | Medical sciences | Staphylococcus aureus - radiation effects | Staphylococcus epidermidis - drug effects | Drug Resistance, Multiple | Bacteria - drug effects | Drug Resistance, Bacterial | Colony Count, Microbial | Flavin Mononucleotide - pharmacology | Photosensitizing Agents - pharmacology | Candida albicans - drug effects | Ultraviolet Rays | Corneal Ulcer - radiotherapy | Corneal Ulcer - microbiology | Fungi - radiation effects | Staphylococcus epidermidis - radiation effects | Streptococcus pneumoniae - drug effects | Fungi - drug effects | Ultraviolet Therapy | Pseudomonas aeruginosa - radiation effects | Combined Modality Therapy | Pseudomonas aeruginosa - drug effects | Candida albicans - radiation effects | Corneal Ulcer - drug therapy | Bacteria - radiation effects | Staphylococcus aureus - drug effects | Streptococcus pneumoniae - radiation effects | Index Medicus
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8. Full Text Pseudomonas aeruginosa lipopolysaccharide inhibits Candida albicans hyphae formation and alters gene expression during biofilm development
by Bandara, H.M.H.N and K Cheung, B.P and Watt, R.M and Jin, L.J and Samaranayake, L.P
Molecular oral microbiology, ISSN 2041-1006, 02/2013, Volume 28, Issue 1, pp. 54 - 69
hypha | lipopolysaccharide | Pseudomonas | Candida | biofilm | glycolysis | Biofilm | Glycolysis | Lipopolysaccharide | Hypha | Life Sciences & Biomedicine | Microbiology | Dentistry, Oral Surgery & Medicine | Science & Technology | Transcription, Genetic - drug effects | Hyphae - genetics | Proteome - genetics | Humans | Biofilms - growth & development | Adenosine Triphosphatases - drug effects | Hydrolases - drug effects | Sugar Alcohol Dehydrogenases - drug effects | Pseudomonas aeruginosa - physiology | Glycolysis - drug effects | Transcription Factors - drug effects | Candida albicans - genetics | Gene Expression Regulation, Fungal - drug effects | Candida albicans - drug effects | Klebsiella pneumoniae - physiology | Candida albicans - physiology | Microbial Interactions | NADH, NADPH Oxidoreductases - drug effects | Cyclic AMP - analysis | DNA-Binding Proteins - drug effects | Glycine Hydroxymethyltransferase - drug effects | Fungal Proteins - drug effects | Fungal Proteins - genetics | Phosphoglycerate Kinase - drug effects | Lipopolysaccharides - pharmacology | Membrane Glycoproteins - drug effects | Hyphae - drug effects | Genetic research | Pseudomonas aeruginosa | Genetic transcription | Mitogens | Analysis | Genes | Dentistry
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