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Rheumatology (Oxford, England), ISSN 1462-0332, 2019, Volume 58, Issue Supplement_1, pp. i43 - i54
Abstract Janus kinase (JAK)/signal transducers and activators of transcription (STATs) are a group of molecules associated with one of the major pathways... 
FILGOTINIB GLPG0634/GS-6034 | CROHNS-DISEASE | INADEQUATE RESPONSE | PHASE-III | STAT pathway | RHEUMATOLOGY | LONG-TERM EXTENSION | ALOPECIA-AREATA | immune-mediated diseases | CHRONIC PLAQUE PSORIASIS | JAK | JANUS KINASE INHIBITOR | DOUBLE-BLIND | JAK inhibitors | TOFACITINIB-TREATED PATIENTS | Spondylarthropathies - drug therapy | Chilblains - drug therapy | Humans | Dental Enamel Hypoplasia - drug therapy | Metacarpus - abnormalities | Osteoporosis - drug therapy | Immunologic Deficiency Syndromes | Arthritis, Rheumatoid - drug therapy | Lupus Erythematosus, Cutaneous - drug therapy | Arthritis, Psoriatic - drug therapy | Muscular Diseases - drug therapy | Autoimmune Diseases - drug therapy | Inflammatory Bowel Diseases - drug therapy | Psoriasis - drug therapy | Cytokines | Uveitis - drug therapy | Giant Cell Arteritis - drug therapy | Vascular Calcification - drug therapy | Autoimmune Diseases of the Nervous System - drug therapy | Aortic Diseases - drug therapy | Dermatitis, Atopic - drug therapy | Alopecia Areata - drug therapy | Janus Kinase Inhibitors - therapeutic use | Odontodysplasia - drug therapy | Nervous System Malformations - drug therapy | Phosphorylation | Transcription factors | Transcription | Clinical trials | Inflammation | Immunosuppressive agents | Signal transduction | Alopecia | Atopic dermatitis | Rheumatoid arthritis | Janus kinase | Skin diseases | Transduction | Growth factors | Reviews
Journal Article
Journal of the European Academy of Dermatology and Venereology, ISSN 0926-9959, 2016, Volume 30, Issue 7, pp. 1148 - 1158
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 04/2013, Volume 72, Issue 4, pp. 517 - 524
Journal Article
Pharmacological reviews, ISSN 1521-0081, 2015, Volume 67, Issue 2, pp. 280 - 309
.... Cytokines are therefore attractive therapeutic targets in these conditions. Anticytokine therapy for inflammatory diseases became a clinical reality with the introduction of tumor necrosis factor (TNF... 
TUMOR-NECROSIS-FACTOR | MODIFYING ANTIRHEUMATIC DRUGS | COLONY-STIMULATING FACTOR | JUVENILE IDIOPATHIC ARTHRITIS | SEVERE PLAQUE PSORIASIS | ANTI-TNF THERAPY | PHARMACOLOGY & PHARMACY | PLACEBO-CONTROLLED TRIAL | LONG-TERM TREATMENT | ACTIVE ANKYLOSING-SPONDYLITIS | INTERLEUKIN-12/23 MONOCLONAL-ANTIBODY | Drugs, Investigational - adverse effects | Interleukin-6 - antagonists & inhibitors | Humans | Crohn Disease - metabolism | Drugs, Investigational - therapeutic use | Spondylitis, Ankylosing - immunology | Arthritis, Rheumatoid - metabolism | Anti-Inflammatory Agents - adverse effects | Arthritis, Rheumatoid - drug therapy | Arthritis, Psoriatic - drug therapy | Psoriasis - metabolism | Anti-Inflammatory Agents - therapeutic use | Antirheumatic Agents - adverse effects | Interleukin-1 - antagonists & inhibitors | Interleukin-6 - metabolism | Arthritis, Psoriatic - metabolism | Antirheumatic Agents - therapeutic use | Psoriasis - immunology | Interleukin-1 - metabolism | Molecular Targeted Therapy - adverse effects | Psoriasis - drug therapy | Cytokines - metabolism | Spondylitis, Ankylosing - drug therapy | Tumor Necrosis Factors - metabolism | Spondylitis, Ankylosing - metabolism | Crohn Disease - immunology | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Arthritis, Psoriatic - immunology | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Models, Biological | Crohn Disease - drug therapy | Cytokines - antagonists & inhibitors | Arthritis, Rheumatoid - immunology | Tumor Necrosis Factors - antagonists & inhibitors
Journal Article
Journal Article