X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
ptdinsp-2 (110) 110
index medicus (88) 88
animals (83) 83
cell biology (83) 83
biochemistry & molecular biology (81) 81
humans (61) 61
plasma-membrane (54) 54
ptdinsp (50) 50
phosphoinositides (40) 40
activation (39) 39
cell membrane - metabolism (38) 38
phosphatidylinositol 4,5-diphosphate - metabolism (38) 38
signal transduction (34) 34
phosphatidylinositol 4,5-bisphosphate (33) 33
phosphotransferases - metabolism (33) 33
mice (31) 31
ptdinsp-2 synthesis (28) 28
lipids (27) 27
binding (26) 26
ptdinsp2 (26) 26
article (22) 22
phosphatidylinositols - metabolism (22) 22
cells (21) 21
phosphatidylinositol phosphates - metabolism (21) 21
protein binding (21) 21
phospholipase-c (20) 20
endocytosis (19) 19
actin (18) 18
protein (18) 18
proteins (18) 18
biophysics (17) 17
phosphotransferases - genetics (17) 17
phosphoinositide (16) 16
phospholipids (16) 16
cells, cultured (15) 15
phosphorylation (15) 15
protein structure, tertiary (15) 15
protein-kinase-c (15) 15
localization (14) 14
phosphatidylinositol (14) 14
pip2 (14) 14
rats (14) 14
calcium (13) 13
phosphatidylinositol 4,5-diphosphate (13) 13
phospholipase c (13) 13
pleckstrin homology domain (13) 13
actin cytoskeleton (12) 12
binding sites (12) 12
life sciences (12) 12
membrane (12) 12
multidisciplinary sciences (12) 12
pathway (12) 12
calcium - metabolism (11) 11
cell line (11) 11
exocytosis (11) 11
hela cells (11) 11
hydrolysis (11) 11
models, biological (11) 11
mutation (11) 11
receptor (11) 11
4,5-bisphosphate (10) 10
actins - metabolism (10) 10
analysis (10) 10
cytoskeleton (10) 10
expression (10) 10
living cells (10) 10
molecular sequence data (10) 10
neurosciences (10) 10
phagocytosis (10) 10
phosphatidylinositol 4-phosphate 5-kinase (10) 10
physiological aspects (10) 10
ptdinsp 2 (10) 10
cell membrane - enzymology (9) 9
cell membranes (9) 9
kinase (9) 9
kinases (9) 9
membrane proteins - metabolism (9) 9
membrane trafficking (9) 9
phosphate kinase (9) 9
phosphates (9) 9
phosphatidylinositol 3-kinases - metabolism (9) 9
phosphatidylinositols - chemistry (9) 9
time factors (9) 9
translocation (9) 9
4-phosphate 5-kinase (8) 8
amino acid sequence (8) 8
biology (8) 8
ca2 (8) 8
clathrin (8) 8
complex (8) 8
cos cells (8) 8
identification (8) 8
metabolism (8) 8
models, molecular (8) 8
phosphatidic-acid (8) 8
phosphotransferases (8) 8
phosphotransferases - chemistry (8) 8
pikfyve (8) 8
plant sciences (8) 8
ptdins (8) 8
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 11/2009, Volume 122, Issue 21, pp. 3837 - 3850
It has long been known that phosphoinositides are present in cellular membranes, but only in the past four decades has our understanding of their importance... 
PHOSPHATE KINASE | PROTEIN-KINASE-C | PIP5K | PHOSPHOLIPASE-C | RAT-LIVER NUCLEI | PIP5K1 | Phosphatidylinositol 4-phosphate 5-kinase | PLASMA-MEMBRANE | CELL BIOLOGY | Phosphatidylinositol (4,5)-bisphosphate | Phosphatidylinositol | SWISS 3T3-CELLS | PtdIns(4,5)P-2 | INOSITOL 1,4,5-TRISPHOSPHATE | CAENORHABDITIS-ELEGANS | GROWTH-FACTOR-I
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 08/2009, Volume 422, pp. 23 - 35
PtdIns4P is the major precursor for the synthesis of the multifunctional plasma membrane lipid, PtdIns(4,5)P-2. Yet PtdIns4P also functions as a regulatory... 
FIXED CELLS | LOCALIZATION | INOSITOL-POLYPHOSPHATE 5-PHOSPHATASE | plasma membrane | BIOCHEMISTRY & MOLECULAR BIOLOGY | PtdIns4P | BINDING-PROTEIN | HIGH-AFFINITY | PLASMA-MEMBRANE | phosphoinositides | PtdIns(4,5)P-2 | PLECKSTRIN HOMOLOGY DOMAIN | Golgi | ENDOPLASMIC-RETICULUM | immunofluorescence | PHOSPHATIDYLINOSITOL 4-KINASE ISOFORMS
Journal Article
Current Biology, ISSN 0960-9822, 03/2019, Volume 29, Issue 5, pp. 775 - 789.e7
During cytokinesis, an actomyosin contractile ring drives the separation of the two daughter cells. A key molecule in this process is the inositol lipid... 
actin | endosome | PtdIns(4,5)P | cytokinesis | BAR domain protein | IPIP27 | OCRL | SH3PX1 | phosphoinositide | ENDOSOMES | LOWE-SYNDROME | CELL CORTEX | PROTEIN | ACTIN POLYMERIZATION | ANILLIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | RAB35 GTPASE | MEMBRANE-TRAFFICKING | CLEAVAGE FURROW | CELL BIOLOGY
Journal Article
Journal of Cell Science, ISSN 0021-9533, 2015, Volume 128, Issue 22, pp. 4047 - 4056
Phosphoinositides are a collection of lipid messengers that regulate most subcellular processes. Amongst the seven phosphoinositide species, the roles for... 
Protein and membrane trafficking | PIPKI | PtdIns(4,5)P | BECLIN 1 | SORTING NEXIN-1 | DOWN-REGULATION | E-CADHERIN | EXOCYST COMPLEX | CELL BIOLOGY | ENDOSOMAL TRAFFICKING | PtdIns(4,5)P-2 | AUTOPHAGOSOME FORMATION | ENDOPLASMIC-RETICULUM | PHOSPHATIDYLINOSITOL-PHOSPHATE KINASE | EGF RECEPTOR
Journal Article
EMBO JOURNAL, ISSN 0261-4189, 02/2015, Volume 34, Issue 4, pp. 475 - 490
Lysosomal degradation is essential for the termination of EGF-stimulated EGF receptor (EGFR) signaling. This requires EGFR sorting to the intraluminal vesicles... 
PIPKI gamma i5 | GROWTH-FACTOR-RECEPTOR | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | TRAFFICKING | EGFR | CELL BIOLOGY | LAPTM4B | HEPATOCELLULAR-CARCINOMA | PtdIns(4,5) P-2 | MULTIVESICULAR ENDOSOMES | ESCRT MACHINERY | ION CHANNELS | MULTIDRUG-RESISTANCE | CELL REGULATION
Journal Article
Journal of cell science, ISSN 0021-9533, 2010, Volume 123, Issue 20, pp. 3535 - 3546
In N1E-115 cells, neurite retraction induced by neurite remodelling factors such as lysophosphatidic acid, sphingosine 1-phosphate and semaphorin 3A require... 
ACTIVATION | BINDING PROTEIN-RHO | PIP5K | PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE | ACTIN-FILAMENTS | Neurite retraction | CELL BIOLOGY | ADHESION | kinase | I-ALPHA | PtdIns(4,5)P-2 | LYSOPHOSPHATIDIC ACID | Rac | NEURONAL CELLS | RETRACTION | G-proteins | PHOSPHATE KINASES | PIP2
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 03/2013, Volume 126, Issue 5, pp. 1247 - 1259
The prototypical transient receptor potential (TRP) channel is the major light-sensitive, and Ca2+-permeable channel in the microvillar photoreceptors of... 
Rhodopsin | ERM PROTEINS | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | LIGHT RESPONSE | Moesin | PHOTORECEPTOR CELL | PLASMA-MEMBRANE | TRP channels | CELL BIOLOGY | PtdIns(4,5)P-2 | Actin | IN-VIVO | BINDING-SITE | ACTIN CYTOSKELETON | RECEPTOR POTENTIAL CHANNEL
Journal Article
FEBS Journal, ISSN 1742-464X, 2019, Volume 286, Issue 11, pp. 2216 - 2234
Entamoeba histolytica is an intestinal protist parasite that causes amoebiasis, a major source of morbidity and mortality in developing countries.... 
phosphatidylinositol phosphate kinase | Entamoeba histolytica | PtdInsP | PtdIns(4,5)P | EhPIPKI | PHAGOCYTOSIS | PROTEIN | ACTIN | CYTOSKELETON | BIOCHEMISTRY & MOLECULAR BIOLOGY | Entamoeba histolytica | PHOSPHOINOSITIDES | 4,5-BISPHOSPHATE | ROLES | PtdIns | PHOSPHATE KINASES | BINDING | EXPRESSION | 5)P-2
Journal Article
The EMBO Journal, ISSN 0261-4189, 04/2011, Volume 30, Issue 8, pp. 1433 - 1443
Phosphorylation of the Wnt receptor low-density lipoprotein receptor-related protein 6 (LRP6) by glycogen synthase kinase 3b (GSK3 beta) and casein kinase 1... 
AXIN | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CORECEPTOR LRP6 | TRANSDUCTION | BETA-CATENIN | PROTEIN ASSEMBLIES | PLASMA-MEMBRANE | WILMS-TUMOR | LRP6 | CELL BIOLOGY | PtdIns(4,5)P-2 | SIGNALING PATHWAY | WTX | Wnt | Amer1
Journal Article
Traffic, ISSN 1398-9219, 06/2018, Volume 19, Issue 6, pp. 436 - 445
Phosphoinositides (PtdIns) play important roles in exocytosis and are thought to regulate secretory granule docking by co-clustering with the SNARE protein... 
PtdIns(4,5)P | insulin | syntaxin clustering | exocytosis | vesicle docking | live cell imaging | phosphoinositides | SYNTAXIN CLUSTERS | CHROMAFFIN CELLS | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | INSULIN-SECRETION | BINDING-PROTEIN | PLASMA-MEMBRANE | CELL BIOLOGY | MODEL MEMBRANES | PtdIns(4,5)P-2 | PLECKSTRIN HOMOLOGY DOMAIN | DENSE-CORE VESICLES | ENDOCRINE-CELLS
Journal Article
Traffic, ISSN 1398-9219, 09/2018, Volume 19, Issue 9, pp. 655 - 665
The human immunodeficiency virus type 1 (HIV-1) transactivator of transcription (Tat) protein functions both intracellularly and extracellularly.... 
HIV-1 | PtdIns(4,5)P | secretion | T-cell | Tat | astrocyte | exosome | monocyte-macrophage | VIRUS TYPE-1 TAT | UNCONVENTIONAL PROTEIN SECRETION | GROWTH-FACTOR 2 | CELL-PENETRATING PEPTIDES | PLASMA-MEMBRANE | CELL BIOLOGY | PtdIns(4,5)P-2 | MULTIVESICULAR BODIES | GENE-EXPRESSION | NEUROCOGNITIVE DISORDERS | HEPARAN-SULFATE PROTEOGLYCANS | NF-KAPPA-B
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 06/2010, Volume 123, Issue 12, pp. 2057 - 2066
The ezrin, radixin and moesin (ERM) proteins regulate cell membrane architecture in several cellular contexts. Current models propose that ERM activation... 
FERM DOMAIN | Moesin | MEMBRANE | MECHANISMS | MICROTUBULE ORGANIZATION | CELL BIOLOGY | EPITHELIAL INTEGRITY | MORPHOGENESIS | PtdIns(4,5)P-2 | EZRIN | EZRIN/RADIXIN/MOESIN ERM PROTEINS | GENE-EXPRESSION | ACTIN-BINDING-SITE | Drosophila morphogenesis | Actin cytoskeleton | ERM proteins
Journal Article
CELLULAR MICROBIOLOGY, ISSN 1462-5814, 10/2019, Volume 21, Issue 10
Motility and phagocytosis are the two important processes that are intricately linked to survival and virulence potential of the protist parasite Entamoeba... 
phagocytosis | PROTEIN | MEMBRANE | MICROBIOLOGY | pseudopod | PHOSPHOINOSITIDES | CELL BIOLOGY | PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE | actin | phosphatidylinositol | CALCIUM | motility | 5)bisphosphate (PtdIns | EhPIPKI | BINDING | SERINE-RICH | 5)P-2
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 11/2000, Volume 113, Issue 21, pp. 3685 - 3695
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 05/2010, Volume 123, Issue 9, pp. 1492 - 1502
Phosphoinositides regulate numerous processes in various subcellular compartments. Whereas many stimuli trigger changes in the plasma-membrane PtdIns(4,5)P-2... 
PLECKSTRIN HOMOLOGY DOMAINS | ACTIVATION | PHOSPHATIDYLINOSITOL 4-KINASE | PHOSPHOLIPASE-C | REGULATED EXOCYTOSIS | Oscillations | 4-PHOSPHATE | PtdInsP | Glucose | PI4-kinase | Insulin-secreting cells | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | PtdIns(4,5)P-2 | Ca2 | NEURONAL CALCIUM SENSOR-1 | OXYSTEROL-BINDING-PROTEIN
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 03/2009, Volume 418, pp. 247 - 260
Journal Article
JOURNAL OF MOLECULAR BIOLOGY, ISSN 0022-2836, 04/2008, Volume 377, Issue 4, pp. 1038 - 1052
Rapamycin-triggered heterodimerization strategy is becoming an excellent tool for rapidly modifying phosphatidylinositol(4,5)-bisphosphate [PtdIns (4,5)P-2]... 
rapamycin-triggered heterodimerization | TRANSLOCATION | PROTEIN-KINASE-C | DOMAIN | ACTIVATION | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PKC | C2 domain | siRNA | SIGNAL-TRANSDUCTION | PtdIns(4,5)P-2 | NERVE GROWTH CONES | CA2 | LIPID RAFTS | BINDING
Journal Article
FRONTIERS IN PLANT SCIENCE, ISSN 1664-462X, 2012, Volume 2
The apical plasma membrane of pollen tubes contains different PI4P 5-kinases that all produce phosphatidylinositol-4,5-bisphosphate [PtdIns(4,5)P-2] but exert... 
alternative functions | PtdIns(4,5)P-2 | pollen tubes | membrane association | PI4P 5-kinase | PLANT SCIENCES
Journal Article
Biochemical Journal, ISSN 0264-6021, 08/2014, Volume 461, Issue 3, pp. 521 - 530
c-Fos is a well-recognized member of the AP-1 (activator protein-1) family of transcription factors. In addition to this canonical activity, we previously... 
Activator protein-1 (AP-1) transcription factor | Nuclear phospholipid synthesis | C-Fos-dependent phospholipid synthesis | Phosphatidylinositol 4-monophosphate 5-kinase (Pi4P5K) | Transcription regulation | transcription regulation | INOSITOL LIPIDS | LOCALIZATION | JUN | COMPLEX | activator protein-1 (AP-1) transcription factor | CHROMATIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHOLIPASE-C | RECEPTOR | nuclear phospholipid synthesis | phosphatidylinositol 4-monophosphate 5-kinase (PI4P5K) | phosphatidylinosito1-4,5-bisphosphate [PtdIns(4,5)P-2] | INTERACTS | GENE-EXPRESSION | PHOSPHOINOSITIDE KINASES | c-Fos-dependent phospholipid synthesis | NIH 3T3 Cells | Transcription, Genetic - drug effects | Phosphotransferases (Alcohol Group Acceptor) - chemistry | Cell Nucleus Size - drug effects | Protein Transport - drug effects | Recombinant Fusion Proteins - metabolism | Cell Nucleus - enzymology | Phosphatidylinositol 4,5-Diphosphate - metabolism | Cell Nucleus - metabolism | RNA Interference | Proto-Oncogene Proteins c-fos - antagonists & inhibitors | Recombinant Proteins - metabolism | Proto-Oncogene Proteins c-jun - genetics | Bacterial Proteins - genetics | Enzyme Inhibitors - pharmacology | Proto-Oncogene Proteins c-fos - metabolism | Nuclear Matrix-Associated Proteins - metabolism | Recombinant Proteins - chemistry | Phosphotransferases (Alcohol Group Acceptor) - genetics | Cell Nucleus - ultrastructure | Enzyme Activation - drug effects | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Up-Regulation - drug effects | Phosphotransferases (Alcohol Group Acceptor) - antagonists & inhibitors | Animals | Nuclear Matrix-Associated Proteins - genetics | Proto-Oncogene Proteins c-jun - metabolism | Recombinant Fusion Proteins - genetics | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Proto-Oncogene Proteins c-fos - genetics | Cell Proliferation - drug effects | Mice | Cell Nucleus - drug effects | Luminescent Proteins - metabolism
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.