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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2010, Volume 107, Issue 44, pp. 18880 - 18885
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2012, Volume 122, Issue 6, pp. 2032 - 2045
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 08/2015, Volume 53, Issue 2, pp. 159 - 173
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 07/2013, Volume 188, Issue 1, pp. 60 - 68
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 01/2018, Volume 314, Issue 1, pp. C73 - C87
Cigarette-smoke (CS) exposure and aging are the leading causes of chronic obstructive pulmonary disease (COPD)-emphysema development, although the molecular... 
Proteostasis | Aging | Cysteamine | Autophagy | Emphysema | Cigarette smoke | COPD | OXIDATIVE STRESS | PHYSIOLOGY | autophagy | AGGRESOME FORMATION | CELL SENESCENCE | cigarette smoke | proteostasis | emphysema | CELL BIOLOGY | OBSTRUCTIVE PULMONARY-DISEASE | PSEUDOMONAS-AERUGINOSA INFECTION | REDOX REGULATION | LIPID-RAFTS | cysteamine | aging | CYSTIC-FIBROSIS | NF-KAPPA-B | PROTEASOMAL INHIBITION | Cysteamine - pharmacology | Epithelial Cells - metabolism | Pulmonary Emphysema - etiology | Epithelial Cells - drug effects | Humans | Cellular Senescence - drug effects | Pulmonary Emphysema - metabolism | Pulmonary Disease, Chronic Obstructive - etiology | Pulmonary Disease, Chronic Obstructive - pathology | Autophagy - drug effects | Case-Control Studies | Ubiquitination | Inflammation Mediators - metabolism | Lung - ultrastructure | Lung - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Inclusion Bodies - metabolism | Sequestosome-1 Protein - metabolism | Disease Models, Animal | Severity of Illness Index | Cell Line | Cigarette Smoking - adverse effects | Inclusion Bodies - ultrastructure | Cytokines - metabolism | Smoke - adverse effects | Mice, Inbred C57BL | Epithelial Cells - ultrastructure | Pulmonary Emphysema - pathology | Pulmonary Emphysema - drug therapy | Disease Progression | Animals | Lung - drug effects | Pulmonary Disease, Chronic Obstructive - drug therapy
Journal Article
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 09/2017, Volume 57, Issue 3, pp. 367 - 375
Journal Article
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 11/2014, Volume 51, Issue 5, pp. 709 - 720
Whereas cigarette smoking remains the main risk factor for emphysema, recent studies in beta-epithelial Na+ channel-transgenic (beta ENaC-Tg) mice demonstrated... 
Airway surface liquid | Cystic fibrosis | Chronic obstructive pulmonary disease | Inflammation | Mucus | SURFACE DEHYDRATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FIBROSIS LUNG-DISEASE | LESSONS | mucus | CELL BIOLOGY | PATHOGENESIS | inflammation | RESPIRATORY SYSTEM | cystic fibrosis | CHANNEL-OVEREXPRESSING MICE | ELASTASE | GENE-EXPRESSION | airway surface liquid | CYSTIC-FIBROSIS | PULMONARY-DISEASE | chronic obstructive pulmonary disease | Genomics | Bronchoalveolar Lavage Fluid - immunology | Matrix Metalloproteinase 12 - genetics | Pulmonary Emphysema - metabolism | STAT6 Transcription Factor - genetics | Airway Obstruction - metabolism | Cystic Fibrosis - immunology | Signal Transduction - immunology | Airway Obstruction - immunology | Mucus - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Macrophages, Alveolar - immunology | Cystic Fibrosis - metabolism | Macrophage Activation - immunology | Dehydration - immunology | Matrix Metalloproteinase 12 - immunology | Matrix Metalloproteinase 12 - metabolism | STAT6 Transcription Factor - metabolism | STAT6 Transcription Factor - immunology | Pulmonary Emphysema - immunology | Mice, Knockout | Animals | Cystic Fibrosis - genetics | Polymorphism, Single Nucleotide - genetics | Mucus - immunology | Macrophages, Alveolar - metabolism | Pulmonary Disease, Chronic Obstructive - immunology | Dehydration - metabolism | Studies | Lungs | Microscopy | Pathogenesis | Rodents | Lung diseases | Genomes | Cigarettes | Gene expression | Emphysema
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, p. e20333
Chronic Obstructive Pulmonary Disease (COPD) is characterized by airspace enlargement and peribronchial lymphoid follicles; however, the immunological... 
OBSTRUCTIVE PULMONARY-DISEASE | CYTOKINE PRODUCTION | ARYL-HYDROCARBON RECEPTOR | AUTOIMMUNITY | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | PERIPHERAL-BLOOD | MICE | T-CELLS | BRONCHOALVEOLAR LAVAGE | Adjuvants, Immunologic - pharmacology | Humans | Bronchoalveolar Lavage | Matrix Metalloproteinase 12 - genetics | Transcriptional Activation - immunology | Tobacco - immunology | Receptors, Aryl Hydrocarbon - metabolism | Female | Th17 Cells - cytology | Chemokine CCL2 - metabolism | Receptors, Interleukin-17 - metabolism | Bronchi - cytology | Macrophages - immunology | Gene Expression Regulation - immunology | Smoke - adverse effects | Emphysema - metabolism | Chemokine CCL2 - genetics | Mucous Membrane - metabolism | Emphysema - etiology | Cell Differentiation - immunology | Emphysema - immunology | Macrophages - metabolism | Animals | Sequence Analysis, RNA | Mucous Membrane - immunology | Th17 Cells - immunology | Mice | Matrix Metalloproteinase 3 - genetics | Respiratory tract diseases | Macrophages | Cell differentiation | Emphysema, Pulmonary | Smoking | Disease | Helper cells | Hydrocarbons | Science | Lymphocytes T | Smoke | Follicles | Recruitment | Immunology | Aromatic compounds | Lymphocytes | Rodents | Chronic obstructive pulmonary disease | Enlargement | Tobacco smoke | Cytokines | Lung diseases | Inflammation | Gene expression | Cigarettes | Airspace | Medicine | Signaling | Obstructive lung disease | Ligands | Autoimmune diseases | Emphysema | Chemokines | Monocyte chemoattractant protein 1 | Cigarette smoke
Journal Article