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Neuropharmacology, ISSN 0028-3908, 05/2016, Volume 104, pp. 31 - 49
Pharmacological tool compounds are now available to define action at the adenosine (ARs), P2Y and P2X receptors. We present a selection of the most commonly... 
Nucleosides | GPCR | Agonists | Antagonists | Nucleotides | Ion channel | ATP | PROTEIN-COUPLED RECEPTORS | ALLOSTERIC MODULATION | NEUROSCIENCES | NEUROPATHIC PAIN | NUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE | IN-VIVO | ION-CHANNEL | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | PURINERGIC RECEPTOR | P2Y RECEPTOR | STRUCTURE-BASED DESIGN | Purinergic P1 Receptor Agonists - chemistry | Receptors, Purinergic P2Y - chemistry | Receptors, Purinergic P2X - chemistry | Humans | Purinergic P1 Receptor Agonists - pharmacology | Receptors, Purinergic P2Y - metabolism | Purinergic P1 Receptor Antagonists - therapeutic use | Purinergic P2Y Receptor Agonists - chemistry | Purinergic P2Y Receptor Agonists - therapeutic use | Structure-Activity Relationship | Purinergic P1 Receptor Agonists - therapeutic use | Chemistry, Pharmaceutical | Purinergic P1 Receptor Antagonists - pharmacology | Purinergic P2Y Receptor Agonists - pharmacology | Receptors, Purinergic P1 - chemistry | Animals | Purinergic Agents - chemistry | Purinergic Agents - therapeutic use | Receptors, Purinergic P2X - metabolism | Receptors, Purinergic P1 - metabolism | Purinergic Agents - pharmacology | Purinergic P1 Receptor Antagonists - chemistry | Prevention | Brain | Purines | Enzymes | Injuries | Chronic pain | Cancer | antagonists | nucleosides | agonists | ion channel | nucleotides
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2009, Volume 284, Issue 36, pp. 24035 - 24048
The role of endogenous inducers of inflammation is poorly understood. To produce the proinflammatory master cytokine interleukin (IL)-1β, macrophages need... 
GENE | LEUCINE-RICH PROTEOGLYCANS | CASPASE-1 | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | INNATE IMMUNE-RESPONSE | HYALURONAN | IL-1-BETA | SECRETION | ATP | NALP3 INFLAMMASOME | Toll-Like Receptor 2 - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Immunity, Innate - genetics | Extracellular Matrix - metabolism | Caspase 1 - metabolism | Male | Ureteral Obstruction - metabolism | Interleukin-1beta - genetics | Inflammation - metabolism | Kidney - metabolism | Carrier Proteins - immunology | Signal Transduction | Proteoglycans - immunology | Extracellular Matrix Proteins - genetics | Proteoglycans - metabolism | Toll-Like Receptor 4 - genetics | Biglycan | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Ureteral Obstruction - immunology | Macrophages - metabolism | Receptors, Purinergic P2 - metabolism | Toll-Like Receptor 2 - immunology | Mice | Proteoglycans - genetics | Extracellular Matrix - immunology | Kidney - immunology | Caspase 1 - immunology | Extracellular Matrix - genetics | Receptors, Purinergic P2 - genetics | Ureteral Obstruction - genetics | Interleukin-1beta - biosynthesis | Lung - metabolism | Receptors, Purinergic P2 - immunology | Extracellular Matrix Proteins - metabolism | Macrophages - immunology | Carrier Proteins - biosynthesis | Interleukin-1beta - immunology | Inflammation - immunology | Protein Structure, Tertiary - genetics | Receptors, Purinergic P2X7 | Carrier Proteins - genetics | Immunity, Innate - immunology | Animals | Caspase 1 - genetics | Extracellular Matrix Proteins - immunology | Receptors, Purinergic P2X4 | Inflammation - genetics | Lung - immunology | Animal models | Reactive oxygen species | Oligomerization | Proteoglycans | Transcription | Lung | Inflammation | Macrophages | Kidney | Stress | Caspase-1 | Purine P2X receptors | Signal transduction | Cell activation | TLR2 protein | Interleukin 1 | Toll-like receptors | Extracellular matrix | Sepsis | Cooperativity | Injuries | Glycobiology and Extracellular Matrices
Journal Article
Journal Article
Annual Review of Physiology, ISSN 0066-4278, 2/2019, Volume 81, Issue 1, pp. 43 - 62
Journal Article
The Neuroscientist, ISSN 1073-8584, 10/2012, Volume 18, Issue 5, pp. 422 - 438
Journal Article