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Neuropharmacology, ISSN 0028-3908, 2016, Volume 104, pp. 31 - 49
...), P2Y and P2X receptors. We present a selection of the most commonly used agents to study purines in the nervous system... 
Nucleosides | GPCR | Agonists | Antagonists | Nucleotides | Ion channel | ATP | PROTEIN-COUPLED RECEPTORS | ALLOSTERIC MODULATION | NEUROSCIENCES | NEUROPATHIC PAIN | NUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE | IN-VIVO | ION-CHANNEL | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | PURINERGIC RECEPTOR | P2Y RECEPTOR | STRUCTURE-BASED DESIGN | Purinergic P1 Receptor Agonists - chemistry | Receptors, Purinergic P2Y - chemistry | Receptors, Purinergic P2X - chemistry | Humans | Purinergic P1 Receptor Agonists - pharmacology | Receptors, Purinergic P2Y - metabolism | Purinergic P1 Receptor Antagonists - therapeutic use | Purinergic P2Y Receptor Agonists - chemistry | Purinergic P2Y Receptor Agonists - therapeutic use | Structure-Activity Relationship | Purinergic P1 Receptor Agonists - therapeutic use | Chemistry, Pharmaceutical | Purinergic P1 Receptor Antagonists - pharmacology | Purinergic P2Y Receptor Agonists - pharmacology | Receptors, Purinergic P1 - chemistry | Animals | Purinergic Agents - chemistry | Purinergic Agents - therapeutic use | Receptors, Purinergic P2X - metabolism | Receptors, Purinergic P1 - metabolism | Purinergic Agents - pharmacology | Purinergic P1 Receptor Antagonists - chemistry | Prevention | Brain | Purines | Enzymes | Injuries | Chronic pain | Cancer | antagonists | nucleosides | agonists | ion channel | nucleotides
Journal Article
Purinergic Signalling, ISSN 1573-9538, 9/2012, Volume 8, Issue 3, pp. 419 - 436
...) and the eight subtypes of P2Y receptors (P2YRs, activated by a range of purine and pyrimidine mono- and dinucleotides... 
Clinical trials, nucleosides | Neurosciences | Adenosine receptors | Human Physiology | P2Y receptors | Antagonists | Nucleotides | Biomedicine general | Biomedicine | GPCR structure | Cancer Research | Agonists | Pharmacology/Toxicology | PHYLOGENETIC ANALYSIS | A(2B) ADENOSINE | ANTAGONIST RECOGNITION | SITE-DIRECTED MUTAGENESIS | MUTATIONAL ANALYSIS | NEUROSCIENCES | NUCLEOTIDE RECEPTORS | INTERNATIONAL UNION | SUBTYPE SELECTIVITY | MOLECULAR RECOGNITION | PURINERGIC RECEPTORS | Receptors, G-Protein-Coupled - metabolism | Humans | Purinergic P2Y Receptor Agonists - therapeutic use | Purinergic P1 Receptor Agonists - therapeutic use | Purinergic P1 Receptor Antagonists - pharmacology | Receptors, Purinergic P1 - chemistry | Receptors, Purinergic P2 - chemistry | Drug Design | Receptors, G-Protein-Coupled - drug effects | Purinergic P2Y Receptor Antagonists - therapeutic use | Purinergic P2Y Receptor Antagonists - pharmacology | Purinergic P1 Receptor Agonists - chemistry | Purinergic P1 Receptor Agonists - pharmacology | Purinergic P1 Receptor Antagonists - therapeutic use | Purinergic P2Y Receptor Agonists - chemistry | Clinical Trials as Topic | Receptors, Purinergic P2 - drug effects | Purinergic P2Y Receptor Agonists - pharmacology | Animals | Purinergic P2Y Receptor Antagonists - chemistry | Receptors, Purinergic P2 - metabolism | Ligands | Receptors, Purinergic P1 - metabolism | Receptors, Purinergic P1 - drug effects | Receptors, G-Protein-Coupled - chemistry | Purinergic P1 Receptor Antagonists - chemistry | Glaucoma | Heart | Adenosine | Parkinson's disease | Psoriasis | Cystic fibrosis | Rheumatoid factor | Hepatitis | Alkaloids | Pyrimidines | Heterocyclic compounds | Emissions (Pollution) | Rheumatoid arthritis | Respiratory tract diseases | Eye diseases | G proteins | Diabetes | Ophthalmology | Kidney diseases | Hepatitis C | DNA-ligand interactions | Arrhythmia | Clinical trials | Ionizing radiation | Reperfusion | Ischemia | pyrimidines | Injuries | Movement disorders | Neurodegenerative diseases | Diabetes mellitus | Lung diseases | Pharmacology | Thrombosis | imaging | Stress | Purine P2Y receptors | purines | Hypoxia | Receptor mechanisms | ATP | Cancer | Pharmaceuticals | Original
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2010, Volume 160, Issue 8, pp. 1953 - 1962
Background and purpose:  P2Y receptors evoke Ca2+ signals in vascular smooth muscle cells and regulate contraction and proliferation, but the roles of the different P2Y receptor subtypes are incompletely resolved... 
UTP | Ca2+ signal | vascular smooth muscle | ATP | ADP | P2Y receptor | UDP-GLUCOSE | ANTAGONIST | ANALOGS | HUMAN P2Y RECEPTOR | PROLIFERATION | AGONIST SELECTIVITY | NUCLEOTIDE RECEPTORS | PHARMACOLOGY & PHARMACY | GROWTH-FACTOR | Ca2+signal | Smooth muscle | Rodents | Muscular system | Cell proliferation | Calcium | Antagonists | Fluorescent indicators | mRNA | Gene expression | Muscle contraction | Calcium influx | Phospholipase C | Calcium signalling | Polymerase chain reaction | Purine P2Y receptors | Plasma membranes | Aorta | Research Papers
Journal Article
American journal of physiology: endocrinology and metabolism, ISSN 1522-1555, 2019, Volume 317, Issue 1, pp. E25 - E41
Fructose is widely used as a sweetener in processed food and is also associated with metabolic disorders, such as obesity. However, the underlying cellular... 
purinergic receptor | APOPTOSIS | pancreatic islet | METABOLIC SYNDROME | ACTIVATION | PHYSIOLOGY | PANNEXIN-1 | fructose | insulin secretion | RELEASE | P2Y RECEPTORS | SWEET TASTE RECEPTOR | ENDOCRINOLOGY & METABOLISM | RESISTANCE | AMPK | BEVERAGES | pannexin | ATP | Islets of Langerhans - drug effects | AMP-Activated Protein Kinases - metabolism | Humans | Receptors, Purinergic P2Y1 - drug effects | Insulin-Secreting Cells - metabolism | Fructose - pharmacology | Islets of Langerhans - metabolism | Adenosine Triphosphate - metabolism | Receptors, Purinergic P2Y1 - metabolism | Receptors, Purinergic P2Y - drug effects | Adenosine Triphosphate - physiology | Insulin Secretion - drug effects | Purinergic P2Y Receptor Antagonists - pharmacology | Mice, Inbred C57BL | Apyrase - metabolism | Receptors, Purinergic P2Y - metabolism | Connexins - genetics | Glucose - pharmacology | Nerve Tissue Proteins - genetics | Connexins - metabolism | Purinergic P2Y Receptor Agonists - pharmacology | Nerve Tissue Proteins - metabolism | Animals | Insulin-Secreting Cells - drug effects | Signal Transduction - drug effects | Mice | AMP-Activated Protein Kinases - genetics | Calcium | Purine receptors | Insulinoma | Glucose | Kinases | Exocytosis | AMP-activated protein kinase | Channels | Mimicry | Chronic exposure | Receptors | Mitochondria | Pancreas | Calcium channels | AMP | Exposure | Food processing | Insulin | Fructose | Signaling | Purine P2Y receptors | Inhibitors | Apyrase | Ectonucleotidase | Human behavior | Metabolic disorders
Journal Article