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1964, Commonwealth and international library. A Course in organic chemistry, advanced section, v. 25, vii, 79 p. illus.
Book
European Journal of Medicinal Chemistry, ISSN 0223-5234, 10/2014, Volume 85, pp. 418 - 437
The 2′-deoxynucleoside 5′-phosphate N-hydrolase 1 (DNPH1) has been proposed as a new molecular target for cancer treatment. Here, we describe the synthesis of... 
Inhibitor | Cross-coupling reaction | DNPH1 | Nucleoside analogues | Crystal structure | Cancer | 5'-MONOPHOSPHATE N-GLYCOSIDASE | CHEMISTRY, MEDICINAL | CYTOSTATIC 6-ARYLPURINE NUCLEOSIDES | C-MYC | HL-60 CELLS | LEAVING GROUPS | 2'-DEOXYRIBONUCLEOSIDE 5'-MONOPHOSPHATE | ANTICANCER ACTIVITY | CROSS-COUPLING REACTIONS | PROTEIN-LIGAND COMPLEXES | HYDROLASE RCL | Purine Nucleotides - pharmacology | Antineoplastic Agents - chemical synthesis | Humans | Proto-Oncogene Proteins - chemistry | Structure-Activity Relationship | Enzyme Inhibitors - chemical synthesis | Molecular Targeted Therapy | Purine Nucleotides - chemistry | N-Glycosyl Hydrolases - chemistry | Purine Nucleotides - metabolism | Antineoplastic Agents - metabolism | Enzyme Inhibitors - chemistry | Drug Design | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Chemistry Techniques, Synthetic | Enzyme Inhibitors - metabolism | N-Glycosyl Hydrolases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Rats | Nuclear Proteins - metabolism | Purine Nucleotides - chemical synthesis | Antineoplastic Agents - chemistry | Nuclear Proteins - chemistry | N-Glycosyl Hydrolases - metabolism | Animals | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Protein Conformation | Molecular Docking Simulation | Drug Screening Assays, Antitumor | Enzymes | Colon cancer | Leukemia | Crystals | Hydrolases | Nucleotides | Structure | Nuclear Proteins/chemistry | Purine Nucleotides/metabolism | Proto-Oncogene Proteins/antagonists & inhibitors | Enzyme Inhibitors/metabolism | Enzyme Inhibitors/pharmacology | Life Sciences | Antineoplastic Agents/pharmacology | N-Glycosyl Hydrolases/antagonists & inhibitors | Nuclear Proteins/antagonists & inhibitors | N-Glycosyl Hydrolases/metabolism | Nuclear Proteins/metabolism | Purine Nucleotides/chemistry | Enzyme Inhibitors/chemistry | Purine Nucleotides/chemical synthesis | Enzyme Inhibitors/chemical synthesis | Antineoplastic Agents/metabolism | N-Glycosyl Hydrolases/chemistry | Proto-Oncogene Proteins/chemistry | Biochemistry, Molecular Biology | Proto-Oncogene Proteins/metabolism | Purine Nucleotides/pharmacology | Antineoplastic Agents/chemistry | Antineoplastic Agents/chemical synthesis
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2011, Volume 82, Issue 4, pp. 358 - 370
We characterize interactions of 21 (M)ANT-nucleotides with mammalian adenylyl cyclases. Through combination of enzymological, fluorescence spectroscopy and... 
Fluorescence spectroscopy | Conformational landscape | Molecular modelling | Adenylyl Cyclase | MANT-nucleotides | ISOFORMS | PROTEIN | DRUG DISCOVERY | EDEMA FACTOR | DIFFERENTIAL INTERACTIONS | SOLUBLE GUANYLYL CYCLASE | INHIBITION | NUCLEOSIDE 5'-TRIPHOSPHATES | BACILLUS-ANTHRACIS | PHARMACOLOGY & PHARMACY | FORSKOLIN ANALOGS | Cell Line | Catalytic Domain | ortho-Aminobenzoates - chemistry | Pyrimidine Nucleotides - chemistry | Guanosine Triphosphate - analogs & derivatives | Models, Molecular | Spectrometry, Fluorescence | Guanosine Triphosphate - metabolism | Structure-Activity Relationship | Adenylyl Cyclases - metabolism | Mammals | Purine Nucleotides - chemistry | Purine Nucleotides - metabolism | Adenosine Triphosphate - analogs & derivatives | Pyrimidine Nucleotides - metabolism | Spodoptera | Animals | Adenosine Triphosphate - metabolism | Guanosine Triphosphate - chemistry | Adenosine Triphosphate - chemistry | ortho-Aminobenzoates - metabolism | Protein Binding - physiology | Fluorescence | Nucleosides | Pyrimidines | Analysis | Pyrimidine nucleotides | Drugs | Enzymes | Landscape | pharmacophores | Adenine | fluorescence spectroscopy | Nucleotides | Xanthine | Structure-activity relationships | Guanine | Adenylate cyclase | Signal transduction | Ribose | Phosphate | purines | Hypoxanthine | Cytosine | pyrimidines | Uracil | Index Medicus | Life Sciences | Pharmacology | Pharmaceutical sciences | conformational landscape | molecular modeling
Journal Article
2003, Methods in molecular biology, ISBN 9780896039681, Volume 212., xi, 269
Single nucleotide polymorphisms (SNPs) have become the markers of choice in elucidating the relationship between DNA sequence variation and susceptibility to... 
Chromosome polymorphism | Genetic markers | Variation | Human genetics | Laboratory manuals | Human Genetics | Biomedicine
Book
Journal Article
Synlett, ISSN 0936-5214, 09/2011, Volume 22, Issue 14, pp. 1956 - 1964
Abstract The origins of life represent one of the most fundamental chemical questions being addressed by modern science. One of the longstanding mysteries of... 
synpacts | chemoselectivity | multicomponent reactions | photochemistry | nucleotides | rearrangement | RNA | PHOSPHORYLATION | PREBIOTIC SYNTHESIS | RIBOSE | CHEMISTRY, ORGANIC | POLYMERIZATION | RIBONUCLEOTIDES | ALPHA-AMINONITRILES | PURINE PRECURSORS | AMINO-ACIDS | OLIGOMERIZATION
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 05/2019, Volume 25, Issue 30, pp. 7387 - 7395
Nucleotides that contain two nucleobases (double‐headed nucleotides) have the potential to condense the information of two separate nucleotides into one. This... 
2,6-diaminopurine | oligonucleotides | hypoxanthine | double-headed nucleotides | VISUALIZATION | DEOXYINOSINE | STABILIZATION | POLYMERASE | INFORMATION-STORAGE | CHEMISTRY, MULTIDISCIPLINARY | VERSATILE | DNA | MINOR-GROOVE | Purines | Pyrimidines | Analysis | Molecular dynamics | Nucleotides | Sugars | Monosaccharides | DNA biosynthesis | Arabinose | Thymine | Oligonucleotides | Adenine | Hypoxanthine | Cytosine | Guanine | Deoxyribonucleic acid--DNA
Journal Article
Journal Article
Molecular Microbiology, ISSN 0950-382X, 06/2016, Volume 100, Issue 5, pp. 824 - 840
Journal Article
Cancer Cell, ISSN 1535-6108, 11/2017, Volume 32, Issue 5, pp. 624 - 638.e5
Journal Article
Analytical Biochemistry, ISSN 0003-2697, 2004, Volume 332, Issue 2, pp. 321 - 329
Journal Article