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1. Full Text P2 receptors and cancer
by White, Nicholas and Burnstock, Geoffrey
Trends in pharmacological sciences (Regular ed.), ISSN 0165-6147, 2006, Volume 27, Issue 4, pp. 211 - 217
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Carcinoma, Non-Small-Cell Lung - metabolism | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Purinergic P2 Receptor Agonists | Receptors, Purinergic P2 - drug effects | Randomized Controlled Trials as Topic | Adenosine Triphosphate - pharmacology | Neoplasms, Experimental - pathology | Adenosine Triphosphate - therapeutic use | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Receptors, Purinergic P2 - metabolism | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasms, Experimental - metabolism | Neoplasms, Experimental - drug therapy | Causes of | Cell receptors | Research | Cancer | Cell research | Care and treatment | Analysis | Oncology, Experimental | Index Medicus
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2. Full Text G protein-coupled adenosine (P1) and P2Y receptors: ligand design and receptor interactions
by Jacobson, Kenneth A and Balasubramanian, Ramachandran and Deflorian, Francesca and Gao, Zhan-Guo
Purinergic signalling, ISSN 1573-9538, 9/2012, Volume 8, Issue 3, pp. 419 - 436
Clinical trials, nucleosides | Neurosciences | Adenosine receptors | Human Physiology | P2Y receptors | Antagonists | Nucleotides | Biomedicine general | Biomedicine | GPCR structure | Cancer Research | Agonists | Pharmacology/Toxicology | Biochemistry & Molecular Biology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Receptors, G-Protein-Coupled - metabolism | Humans | Purinergic P2Y Receptor Agonists - therapeutic use | Purinergic P1 Receptor Agonists - therapeutic use | Purinergic P1 Receptor Antagonists - pharmacology | Receptors, Purinergic P1 - chemistry | Receptors, Purinergic P2 - chemistry | Drug Design | Receptors, G-Protein-Coupled - drug effects | Purinergic P2Y Receptor Antagonists - therapeutic use | Purinergic P2Y Receptor Antagonists - pharmacology | Purinergic P1 Receptor Agonists - chemistry | Purinergic P1 Receptor Agonists - pharmacology | Purinergic P1 Receptor Antagonists - therapeutic use | Purinergic P2Y Receptor Agonists - chemistry | Clinical Trials as Topic | Receptors, Purinergic P2 - drug effects | Purinergic P2Y Receptor Agonists - pharmacology | Animals | Purinergic P2Y Receptor Antagonists - chemistry | Receptors, Purinergic P2 - metabolism | Ligands | Receptors, Purinergic P1 - metabolism | Receptors, Purinergic P1 - drug effects | Receptors, G-Protein-Coupled - chemistry | Purinergic P1 Receptor Antagonists - chemistry | Glaucoma | Heart | Adenosine | Parkinson's disease | Psoriasis | Cystic fibrosis | Rheumatoid factor | Hepatitis | Alkaloids | Pyrimidines | Heterocyclic compounds | Emissions (Pollution) | Rheumatoid arthritis | Respiratory tract diseases | Eye diseases | G proteins | Diabetes | Ophthalmology | Kidney diseases | Hepatitis C | DNA-ligand interactions | Index Medicus | Arrhythmia | Clinical trials | Ionizing radiation | Reperfusion | Ischemia | pyrimidines | Injuries | Movement disorders | Neurodegenerative diseases | Diabetes mellitus | Lung diseases | Pharmacology | Thrombosis | imaging | Stress | Purine P2Y receptors | purines | Hypoxia | Receptor mechanisms | ATP | Cancer | Pharmaceuticals | Original
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3. Full Text Minor contribution of ATP P2 receptors to electrically-evoked electrographic seizure activity in hippocampal slices: Evidence from purine biosensors and P2 receptor agonists and antagonists
by Lopatář, Ján and Dale, Nicholas and Frenguelli, Bruno G
Neuropharmacology, ISSN 0028-3908, 2011, Volume 61, Issue 1, pp. 25 - 34
Adenosine | Biosensors | ATP | P2Y | P2X | Seizures | Pharmacology & Pharmacy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Electric Stimulation - adverse effects | Seizures - prevention & control | Purines - pharmacology | Rats | Male | Purinergic P2 Receptor Antagonists - therapeutic use | Receptors, Purinergic P2 - physiology | Hippocampus - drug effects | Rats, Sprague-Dawley | Seizures - physiopathology | Purinergic P2 Receptor Agonists - therapeutic use | Animals | Seizures - etiology | Purinergic P2 Receptor Antagonists - pharmacology | Biosensing Techniques - methods | Purinergic P2 Receptor Agonists - pharmacology | Purines - therapeutic use | Hippocampus - physiopathology | Organ Culture Techniques | Medical equipment | Alkaloids | Seizures (Medicine) | Physiological apparatus | Index Medicus | Adenosine A1 receptors | Brain slice preparation | Antagonists | Electrical stimuli | Purine P2X receptors | Anticonvulsants | Purine P2Y receptors | Sensory neurons | purines | Purine P2 receptors
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4. Medicinal chemistry of P2X receptors: Agonists and orthosteric antagonists
by Lambertucci, Catia and Dal Ben, Diego and Buccioni, Michela and Marucci, Gabriella and Thomas, Ajiroghene and Volpini, Rosaria
Current medicinal chemistry, ISSN 0929-8673, 2015, Volume 22, Issue 7, pp. 915 - 928
P2X7 | P2X receptor agonists | P2X6 | P2X3 | P2X2 | P2X5 | P2X4 | P2X receptor antagonists | P2X1 | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Animals | Receptors, Purinergic P2X - chemistry | Humans | Purinergic P2X Receptor Agonists - chemistry | Purinergic P2 Receptor Antagonists - pharmacology | Receptors, Purinergic P2X - metabolism | Purinergic P2 Receptor Antagonists - chemistry | Purinergic P2X Receptor Agonists - pharmacology
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5. Full Text Metabolism of P2 receptor agonists in human airways: Implications for mucociliary clearance and cystic fibrosis
by Picher, Maryse and Burch, Lauranell H and Boucher, Richard C
The Journal of biological chemistry, ISSN 0021-9258, 05/2004, Volume 279, Issue 19, pp. 20234 - 20241
Up-Regulation | Lung - pathology | Epithelial Cells - metabolism | Adenosine Monophosphate - metabolism | Cystic Fibrosis - metabolism | Humans | Cells, Cultured | Inflammation | Purinergic P2 Receptor Agonists | Chromatography, High Pressure Liquid | Nucleotides - metabolism | RNA, Messenger - metabolism | Cilia - metabolism | Ribonucleases - metabolism | Mucous Membrane - pathology | Time Factors | Adenosine Triphosphate - metabolism | Adenosine - metabolism | Bronchi - metabolism | Adenosine Diphosphate - metabolism | Index Medicus
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6. Full Text Purine and pyrimidine receptors
by Burnstock, G
Cellular and molecular life sciences : CMLS, ISSN 1420-682X, 06/2007, Volume 64, Issue 12, pp. 1471 - 1483
Biochemistry, general | G protein-coupled receptors | heteromultimers | P2X receptor | Biomedicine general | Cell Biology | Life Sciences | Life Sciences, general | gene regulation | P2Y receptor | P1 receptor | Cloned receptors | ion channel receptors | Heteromultimers | Gene regulation | Ion channel receptors | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Purines - metabolism | Humans | Transcriptional Activation | Gene Expression Regulation | Purinergic P2 Receptor Agonists | Pyrimidines - metabolism | Receptors, Purinergic P1 - chemistry | Receptors, Purinergic P2 - chemistry | Animals | Adenosine Triphosphate - metabolism | Receptors, Purinergic P2 - metabolism | Receptors, Purinergic P1 - metabolism | Purinergic P1 Receptor Agonists | Dimerization | Ions | Molecular biology | Cloning | Genomics | Index Medicus
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7. Full Text Enhanced Potency of Nucleotide−Dendrimer Conjugates as Agonists of the P2Y14 Receptor: Multivalent Effect in G Protein-Coupled Receptor Recognition
by Das, Arijit and Zhou, Yixing and Ivanov, Andrei A and Carter, Rhonda L and Harden, T. Kendall and Jacobson, Kenneth A
Bioconjugate chemistry, ISSN 1043-1802, 08/2009, Volume 20, Issue 8, pp. 1650 - 1659
Uridine Diphosphate Glucuronic Acid - chemistry | Polyamines - chemistry | Uridine Diphosphate Glucuronic Acid - pharmacology | Humans | Molecular Conformation | Cells, Cultured | Structure-Activity Relationship | Purinergic P2 Receptor Agonists - chemistry | Receptors, Purinergic P2 - chemistry | Polyamines - pharmacology | Receptors, Purinergic P2 - metabolism | Dendrimers - chemistry | Purinergic P2 Receptor Agonists - pharmacology | Dendrimers - pharmacology | Index Medicus
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8. Full Text Agonist-selective, receptor-specific interaction of human P2Y receptors with β-arrestin-1 and -2
by Hoffmann, Carsten and Ziegler, Nicole and Reiner, Susanne and Krasel, Cornelius and Lohse, Martin J
The Journal of biological chemistry, ISSN 0021-9258, 11/2008, Volume 283, Issue 45, pp. 30933 - 30941
Humans | Uridine Triphosphate - pharmacology | Cercopithecus aethiops | Arrestins - genetics | Protein Transport - physiology | Protein Transport - drug effects | Purinergic P2 Receptor Agonists | Arrestins - metabolism | Catalytic Domain - physiology | Adenosine Diphosphate - pharmacology | Animals | Signal Transduction - drug effects | beta-Arrestin 2 | beta-Arrestin 1 | beta-Arrestins | Receptors, Purinergic P2 - genetics | Receptors, Purinergic P2 - metabolism | Signal Transduction - physiology | COS Cells | Index Medicus
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9. Full Text Release and interconversion of P2 receptor agonists by human osteoblast‐like cells
by Buckley, K. A and Golding, S. L and Rice, J. M and Dillon, J. P and Gallagher, J. A
The FASEB journal, ISSN 0892-6638, 08/2003, Volume 17, Issue 11, pp. 1401 - 1410
bone | ecto-NDPK | ATP | ADP | ecto-nucleoside diphosphokinase | Ecto-nucleoside diphosphokinase | Bone | Ecto-NDPK | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Nucleoside-Diphosphate Kinase - biosynthesis | Guanosine Triphosphate - pharmacology | Humans | Culture Media, Conditioned - chemistry | Receptors, Purinergic P2Y1 | Adenosine Triphosphate - biosynthesis | RNA, Messenger - metabolism | Dose-Response Relationship, Drug | Receptors, Purinergic P2 - biosynthesis | Adenosine Triphosphate - metabolism | Cell Division | Receptors, Purinergic P2 - genetics | Monomeric GTP-Binding Proteins - biosynthesis | Receptors, Purinergic P2Y12 | Nucleoside-Diphosphate Kinase - genetics | Cell Line | Osteoblasts - enzymology | Adenosine Triphosphate - analysis | Osteoblasts - drug effects | Cells, Cultured | Purinergic P2 Receptor Antagonists | Transcription Factors - biosynthesis | Purinergic P2 Receptor Agonists | Monomeric GTP-Binding Proteins - genetics | Transcription Factors - genetics | Membrane Proteins | Cell Membrane - enzymology | NM23 Nucleoside Diphosphate Kinases | Adenosine Diphosphate - metabolism | Osteoblasts - metabolism | Index Medicus
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10. Full Text International Union of Pharmacology LVIII: Update on the P2Y G Protein-Coupled Nucleotide Receptors: From Molecular Mechanisms and Pathophysiology to Therapy
by Maria P. Abbracchio and Geoffrey Burnstock and Jean-Marie Boeynaems and Eric A. Barnard and José L. Boyer and Charles Kennedy and Gillian E. Knight and Marta Fumagalli and Christian Gachet and Kenneth A. Jacobson and Gary A. Weisman
Pharmacological reviews, ISSN 0031-6997, 09/2006, Volume 58, Issue 3, pp. 281 - 341
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Cardiovascular Diseases - etiology | Atherosclerosis - drug therapy | Cardiovascular Diseases - drug therapy | Cardiovascular Diseases - prevention & control | Humans | Gene Expression Regulation | Models, Molecular | Purinergic P2 Receptor Antagonists | Receptors, Purinergic P2 - physiology | Ion Channels - physiology | Purinergic P2 Receptor Agonists | Phylogeny | Receptors, Purinergic P2 - classification | Protein Isoforms - physiology | Tissue Distribution | Receptors, Purinergic P2 - therapeutic use | Animals | Models, Biological | Second Messenger Systems - physiology | Atherosclerosis - prevention & control | Index Medicus
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