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PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, pp. e19983 - e19983
Background: After ischemia of the CNS, extracellular adenosine 5'-triphosphate (ATP) can reach high concentrations due to cell damage and subsequent increase... 
EXTRACELLULAR ATP | TUMOR-NECROSIS-FACTOR | MICROGLIAL ACTIVATION | TRANSIENT FOREBRAIN ISCHEMIA | BRAIN-INJURY | IL-1-BETA RELEASE | P2X RECEPTORS | MULTIDISCIPLINARY SCIENCES | CEREBRAL-ARTERY OCCLUSION | PURINERGIC MODULATION | NUCLEUS-ACCUMBENS | Immunohistochemistry | In Situ Nick-End Labeling | Rats, Inbred SHR | Infarction, Middle Cerebral Artery - physiopathology | Pyridoxal Phosphate - pharmacology | Pyridoxal Phosphate - therapeutic use | Recovery of Function - drug effects | Motor Activity - drug effects | Rats | Stroke - complications | Male | Purinergic P2 Receptor Antagonists - therapeutic use | Electroencephalography | Stroke - drug therapy | Stroke - physiopathology | Magnetic Resonance Imaging | Rotarod Performance Test | Animals | Time Factors | Infarction, Middle Cerebral Artery - complications | Purinergic P2 Receptor Antagonists - pharmacology | Cell Death - drug effects | Pyridoxal Phosphate - analogs & derivatives | Hypertension | Permeability | Ischemia | Occlusion | Neurosciences | Nuclear magnetic resonance--NMR | Central nervous system | Membrane permeability | Recovery of function | Confocal microscopy | Nervous system | Confocal | Kinases | Recovery | Proteins | Signal transduction | Receptors | Toxicology | Neurodegeneration | Cerebral blood flow | Rodents | Tumor necrosis factor-TNF | Purine P2 receptors | Degeneration | Inhibition | Stroke | Astrocytes | Inflammation | Pharmacology | Frequencies | Hypoglycemia | Studies | Neurology | Magnetic resonance imaging | Microscopy | Magnetic permeability | Neural networks | ATP | Scanning microscopy | Apoptosis | Veins & arteries | Index Medicus | Nuclear magnetic resonance | NMR
Journal Article
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 505, Issue 7482, pp. 223 - 228
Traumatic brain injury (TBI) is increasingly appreciated to be highly prevalent and deleterious to neurological function(1,2). At present, no effective... 
BIOMARKERS | GREEN FLUORESCENT PROTEIN | HEAD-INJURY | INSERTION | STERILE INFLAMMATION | FLUID | CORTEX | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MICE | RELEASE | Encephalitis - prevention & control | Neuroprotective Agents - therapeutic use | Reactive Oxygen Species - metabolism | Brain Injuries - drug therapy | Humans | Astrocytes - pathology | Brain Injuries - complications | Male | Intracranial Hemorrhages - diagnosis | Microglia - physiology | Encephalitis - drug therapy | Glasgow Coma Scale | Purinergic P2 Receptor Antagonists - pharmacology | Encephalitis - complications | Cell Death - drug effects | Neuroprotective Agents - administration & dosage | Disease Models, Animal | Microglia - cytology | Glutathione - therapeutic use | Skull - metabolism | Meninges - pathology | Microglia - drug effects | Neutrophils - drug effects | Neutrophils - physiology | Encephalitis - pathology | Rats | Purinergic P2 Receptor Antagonists - therapeutic use | Meninges - drug effects | Rats, Sprague-Dawley | Brain Injuries - diagnosis | Brain - drug effects | Antioxidants - therapeutic use | Animals | Glutathione - administration & dosage | Receptors, Purinergic P2 - metabolism | Antioxidants - administration & dosage | Brain - pathology | Receptors, Purinergic P2X7 - metabolism | Purinergic P2 Receptor Antagonists - administration & dosage | Mice | Administration, Topical | Brain Injuries - pathology | Intracranial Hemorrhages - complications | Brain | Medical examination | Cell death | Physiological aspects | Skull | Models | Meninges | Observations | Injuries | Brain damage | Emergency medical care | Head injuries | Rodents | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 09/2009, Volume 461, Issue 7261, pp. 282 - 286
Phagocytic removal of apoptotic cells occurs efficiently in vivo such that even in tissues with significant apoptosis, very few apoptotic cells are detectable.... 
UTP | THYMUS | RECEPTOR SUBTYPES | EPITHELIAL-CELLS | CHEMOTAXIS | INFLAMMATION | ENGULFMENT | ELEGANS | MULTIDISCIPLINARY SCIENCES | DEATH | EXTRACELLULAR NUCLEOTIDES | Uridine Triphosphate - metabolism | Monocytes - cytology | Humans | Culture Media, Conditioned - chemistry | Culture Media, Conditioned - pharmacology | Monocytes - metabolism | Receptors, Purinergic P2Y2 | Adenosine Triphosphate - pharmacology | Chemotactic Factors - pharmacology | Chemotactic Factors - metabolism | Adenosine Triphosphate - metabolism | Receptors, Purinergic P2 - genetics | Phagocytes - cytology | Cell Line | Phagocytosis - drug effects | Jurkat Cells | Phagocytes - drug effects | Mice, Inbred C57BL | Uridine Triphosphate - pharmacology | Cells, Cultured | Phagocytosis - physiology | Thymus Gland - cytology | Purinergic P2 Receptor Antagonists | Chemotaxis - drug effects | Macrophages - cytology | Phagocytes - metabolism | Monocytes - drug effects | Macrophages - metabolism | Animals | Signal Transduction - drug effects | Receptors, Purinergic P2 - metabolism | Macrophages - drug effects | Mice | Apoptosis - physiology | Macrophage Activation - drug effects | Receptors, Purinergic P2 - deficiency | Culture Media, Conditioned - metabolism | Phagocytes | Nucleotides | Research | Properties | Apoptosis | Rodents | Cells | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2009, Volume 106, Issue 30, pp. 12489 - 12493
Journal Article