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Neuropharmacology, ISSN 0028-3908, 05/2016, Volume 104, pp. 31 - 49
Pharmacological tool compounds are now available to define action at the adenosine (ARs), P2Y and P2X receptors. We present a selection of the most commonly... 
Nucleosides | GPCR | Agonists | Antagonists | Nucleotides | Ion channel | ATP | PROTEIN-COUPLED RECEPTORS | ALLOSTERIC MODULATION | NEUROSCIENCES | NEUROPATHIC PAIN | NUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE | IN-VIVO | ION-CHANNEL | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | PURINERGIC RECEPTOR | P2Y RECEPTOR | STRUCTURE-BASED DESIGN | Purinergic P1 Receptor Agonists - chemistry | Receptors, Purinergic P2Y - chemistry | Receptors, Purinergic P2X - chemistry | Humans | Purinergic P1 Receptor Agonists - pharmacology | Receptors, Purinergic P2Y - metabolism | Purinergic P1 Receptor Antagonists - therapeutic use | Purinergic P2Y Receptor Agonists - chemistry | Purinergic P2Y Receptor Agonists - therapeutic use | Structure-Activity Relationship | Purinergic P1 Receptor Agonists - therapeutic use | Chemistry, Pharmaceutical | Purinergic P1 Receptor Antagonists - pharmacology | Purinergic P2Y Receptor Agonists - pharmacology | Receptors, Purinergic P1 - chemistry | Animals | Purinergic Agents - chemistry | Purinergic Agents - therapeutic use | Receptors, Purinergic P2X - metabolism | Receptors, Purinergic P1 - metabolism | Purinergic Agents - pharmacology | Purinergic P1 Receptor Antagonists - chemistry | Prevention | Brain | Purines | Enzymes | Injuries | Chronic pain | Cancer | antagonists | nucleosides | agonists | ion channel | nucleotides
Journal Article
Journal Article
Purinergic Signalling, ISSN 1573-9538, 9/2012, Volume 8, Issue 3, pp. 419 - 436
The medicinal chemistry and pharmacology of the four subtypes of adenosine receptors (ARs) and the eight subtypes of P2Y receptors (P2YRs, activated by a range... 
Clinical trials, nucleosides | Neurosciences | Adenosine receptors | Human Physiology | P2Y receptors | Antagonists | Nucleotides | Biomedicine general | Biomedicine | GPCR structure | Cancer Research | Agonists | Pharmacology/Toxicology | PHYLOGENETIC ANALYSIS | A(2B) ADENOSINE | ANTAGONIST RECOGNITION | SITE-DIRECTED MUTAGENESIS | MUTATIONAL ANALYSIS | NEUROSCIENCES | NUCLEOTIDE RECEPTORS | INTERNATIONAL UNION | SUBTYPE SELECTIVITY | MOLECULAR RECOGNITION | PURINERGIC RECEPTORS | Receptors, G-Protein-Coupled - metabolism | Humans | Purinergic P2Y Receptor Agonists - therapeutic use | Purinergic P1 Receptor Agonists - therapeutic use | Purinergic P1 Receptor Antagonists - pharmacology | Receptors, Purinergic P1 - chemistry | Receptors, Purinergic P2 - chemistry | Drug Design | Receptors, G-Protein-Coupled - drug effects | Purinergic P2Y Receptor Antagonists - therapeutic use | Purinergic P2Y Receptor Antagonists - pharmacology | Purinergic P1 Receptor Agonists - chemistry | Purinergic P1 Receptor Agonists - pharmacology | Purinergic P1 Receptor Antagonists - therapeutic use | Purinergic P2Y Receptor Agonists - chemistry | Clinical Trials as Topic | Receptors, Purinergic P2 - drug effects | Purinergic P2Y Receptor Agonists - pharmacology | Animals | Purinergic P2Y Receptor Antagonists - chemistry | Receptors, Purinergic P2 - metabolism | Ligands | Receptors, Purinergic P1 - metabolism | Receptors, Purinergic P1 - drug effects | Receptors, G-Protein-Coupled - chemistry | Purinergic P1 Receptor Antagonists - chemistry | Glaucoma | Heart | Adenosine | Parkinson's disease | Psoriasis | Cystic fibrosis | Rheumatoid factor | Hepatitis | Alkaloids | Pyrimidines | Heterocyclic compounds | Emissions (Pollution) | Rheumatoid arthritis | Respiratory tract diseases | Eye diseases | G proteins | Diabetes | Ophthalmology | Kidney diseases | Hepatitis C | DNA-ligand interactions | Arrhythmia | Clinical trials | Ionizing radiation | Reperfusion | Ischemia | pyrimidines | Injuries | Movement disorders | Neurodegenerative diseases | Diabetes mellitus | Lung diseases | Pharmacology | Thrombosis | imaging | Stress | Purine P2Y receptors | purines | Hypoxia | Receptor mechanisms | ATP | Cancer | Pharmaceuticals | Original
Journal Article
Journal Article
Journal of Computer-Aided Molecular Design, ISSN 0920-654X, 8/2015, Volume 29, Issue 8, pp. 737 - 756
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2010, Volume 53, Issue 24, pp. 8485 - 8497
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2014, Volume 171, Issue 3, pp. 701 - 713
The P2Y₁₄ receptor is the newest member of the P2Y receptor family; it is G(i/o) protein-coupled and is activated by UDP and selectively by UDP-glucose and... 
UDP | endothelium | glucose | receptor | P2Y | vasoconstriction | MRS2690 | Uridine Diphosphate Glucose - agonists | Receptors, Purinergic P2Y - chemistry | Muscle, Smooth, Vascular - metabolism | Vasomotor System - drug effects | Male | Pancreas - blood supply | Arteries - metabolism | Endothelium, Vascular - physiology | Protein Isoforms - metabolism | Protein Isoforms - agonists | Female | Uridine Diphosphate Glucose - analogs & derivatives | Cyclic AMP - metabolism | Muscle, Smooth, Vascular - drug effects | Receptors, Purinergic P2Y - genetics | Recombinant Proteins - metabolism | Vasoconstrictor Agents - pharmacology | Second Messenger Systems - drug effects | Muscle, Smooth, Vascular - innervation | Vasomotor System - metabolism | Vasoconstrictor Agents - antagonists & inhibitors | Nerve Tissue Proteins - agonists | Receptors, Purinergic P2Y - metabolism | Pancreas - drug effects | Recombinant Proteins - chemistry | Purinergic P2Y Receptor Agonists - chemistry | Arteries - drug effects | Pancreas - metabolism | Calcium Channel Blockers - pharmacology | Nerve Tissue Proteins - genetics | Vasoconstriction - drug effects | Purinergic P2Y Receptor Agonists - pharmacology | Nerve Tissue Proteins - metabolism | Cyclic AMP - antagonists & inhibitors | Animals | Uridine Diphosphate Glucose - pharmacology | Calcium Signaling - drug effects | Uridine Diphosphate Glucose - antagonists & inhibitors | Arteries - innervation | Cyclic AMP - agonists | In Vitro Techniques | Sus scrofa | Uridine Diphosphate Glucose - metabolism | Protein Isoforms - genetics | Glucose metabolism | Myosin | Cellulose | Chemical properties | Glucose | Muscle proteins | Arteries | Dextrose | Endothelium | Research Papers | P2Y14 receptor | UDP-glucose
Journal Article
Journal Article