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Clinical cancer research, ISSN 1078-0432, 08/2015, Volume 21, Issue 16, pp. 3705 - 3715
Purpose: Bruton's tyrosine kinase (BTK) is a critical enzyme in the B-cell receptor pathway and is inhibited by ibrutinib due to covalent binding to the kinase... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Piperazines - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Apoptosis - drug effects | Humans | Neoplastic Cells, Circulating - metabolism | Male | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Purines - administration & dosage | Bendamustine Hydrochloride - administration & dosage | Protein-Tyrosine Kinases - genetics | Female | bcl-X Protein - biosynthesis | Protein-Tyrosine Kinases - biosynthesis | B-Cell Activating Factor - biosynthesis | Neoplastic Cells, Circulating - drug effects | Pyrimidines - administration & dosage | Gene Expression Regulation, Leukemic - drug effects | Nitrophenols - administration & dosage | Bridged Bicyclo Compounds, Heterocyclic - administration & dosage | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Pyrazoles - administration & dosage | B-Cell Activating Factor - genetics | Agammaglobulinaemia Tyrosine Kinase | Biphenyl Compounds - administration & dosage | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Aged | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Isoquinolines - administration & dosage | Proto-Oncogene Proteins c-bcl-2 - genetics | Sulfonamides - administration & dosage | Index Medicus
Journal Article
The lancet oncology, ISSN 1470-2045, 07/2018, Volume 19, Issue 7, pp. 904 - 915
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 05/2010, Volume 55, Issue 18, pp. 1915 - 1922
Journal Article
Diabetes care, ISSN 1935-5548, 03/2015, Volume 38, Issue 3, pp. 384 - 393
Journal Article
The New England journal of medicine, ISSN 1533-4406, 11/2016, Volume 375, Issue 18, pp. 1738 - 1748
Journal Article
Breast cancer research and treatment, ISSN 0167-6806, 2/2019, Volume 174, Issue 1, pp. 271 - 278
Journal Article
American journal of physiology. Renal physiology, ISSN 1522-1466, 08/2009, Volume 297, Issue 2, pp. F362 - F370
Sildenafil was the first selective inhibitor of phosphodiesterase-5 (PDE5) to be widely used for treating erectile dysfunction. Many recent studies have... 
Apoptosis | ERK | Physiology | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Piperazines - administration & dosage | Phosphorylation | Apoptosis - drug effects | Blood Urea Nitrogen | Caspase 3 - metabolism | Phosphodiesterase 5 Inhibitors | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Kidney Diseases - enzymology | Purines - administration & dosage | Sildenafil Citrate | Proto-Oncogene Proteins c-bcl-2 - metabolism | Time Factors | Flavonoids - administration & dosage | Nitric Oxide Synthase Type III - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 5 - metabolism | Disease Models, Animal | Drug Administration Schedule | Reperfusion Injury - pathology | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Reperfusion Injury - enzymology | bcl-2-Associated X Protein - metabolism | Rats | Rats, Sprague-Dawley | Phosphodiesterase Inhibitors - administration & dosage | Protein Kinase Inhibitors - administration & dosage | Animals | Reperfusion Injury - prevention & control | Cyclic GMP - metabolism | Creatinine - blood | Nitric Oxide Synthase Type II - metabolism | Sulfones - administration & dosage | Proteins | Side effects | Inhibitor drugs | Ischemia | Rodents | Kidney diseases | Gene expression | Index Medicus
Journal Article
Clinical pharmacokinetics, ISSN 0312-5963, 3/2015, Volume 54, Issue 3, pp. 261 - 272
Journal Article
Journal Article
Journal Article
Annals of internal medicine, ISSN 0003-4819, 10/2008, Volume 149, Issue 8, pp. 521 - 530
Journal Article