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Nature Communications, ISSN 2041-1723, 07/2016, Volume 7, Issue 1, pp. 12338 - 12338
The site-specific insertion of heterologous genetic material into genomes provides a powerful means to study gene function. Here we describe a modular system... 
KNOCK-IN | STEM-CELLS | MEDIATED TARGETED INTEGRATION | HUMAN GENOME | ZEBRAFISH | RNA | DNA | MULTIDISCIPLINARY SCIENCES | HOMOLOGOUS RECOMBINATION | CAS9 | ZINC-FINGER NUCLEASES | Genetic Engineering - methods | Plasmids | Humans | CRISPR-Cas Systems | HEK293 Cells | Reading Frames | Gene Knock-In Techniques | Puromycin | Index Medicus
Journal Article
ChemBioChem, ISSN 1439-4227, 12/2018, Volume 19, Issue 23, pp. 2458 - 2464
Monitoring newly synthesized proteins is becoming increasingly important to characterize proteome composition in regulatory networks. Puromycin is a peptidyl... 
puromycin | analytical chemistry | neuronal control | coumarin | light control | VISUALIZATION | CELLS | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTECTING GROUPS | RELEASE | Proteins | Neurons | Usage | Synthesis | Tagging | Photochemicals | Marking | Hippocampus | Puromycin
Journal Article
BMB Reports, ISSN 1976-6696, 2015, Volume 48, Issue 3, p. 139
Adaptive brain function and synaptic plasticity rely on dynamic regulation of local proteome. One way for the neuron to introduce new proteins to the axon... 
Boyden chamber | Ribosome | BONCAT | Axon | Laser capture microdissection | SILAC | Local mRNA translation | Axon-TRAP | Neuron | Protein synthesis | Campenot chamber | Puromycin tagging | Compartmentalized culture | Microfluidic device
Journal Article
BMB Reports, ISSN 1976-6696, 2015, Volume 48, Issue 3, pp. 139 - 146
Journal Article
Journal Article
ChemBioChem, ISSN 1439-4227, 12/2018, Volume 19, Issue 23, pp. 2423 - 2423
The cover feature picture shows a novel photocaged antibiotic puromycin for the spatiotemporal control and monitoring of nascent polypeptide chain translation.... 
puromycin | analytical chemistry | neuronal control | coumarin | light control
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2006, Volume 2, Issue 6, pp. 0611 - 0622
Journal Article
Journal Article
Nucleic acids research, ISSN 0305-1048, 10/2010, Volume 38, Issue 18, pp. e173 - e173
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2017, Volume 36, Issue 21, pp. 3120 - 3138
The cause of protein accumulation in neurodegenerative disease is incompletely understood. In Alzheimer's disease ( AD ), the axonally enriched protein Tau... 
amyloid‐β | protein synthesis | microtubule‐associated protein Tau | Src kinase Fyn | proximity ligation assay | amyloid-β | microtubule-associated protein Tau | S6 PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CEREBROSPINAL-FLUID | SYNAPTIC PLASTICITY | MOUSE MODELS | CELL BIOLOGY | amyloid-beta | COGNITIVE IMPAIRMENTS | PRION PROTEIN | MESSENGER-RNA | T-CELLS | AMYLOID-BETA OLIGOMERS | TRANSGENIC MICE | Neurons - pathology | Protein Biosynthesis | Ribosomal Protein S6 Kinases - metabolism | Embryo, Mammalian | Humans | Injections, Intraventricular | tau Proteins - metabolism | Male | Alzheimer Disease - pathology | MAP Kinase Signaling System | Proto-Oncogene Proteins c-fyn - genetics | Neurons - ultrastructure | tau Proteins - genetics | Amyloid beta-Protein Precursor - metabolism | HEK293 Cells | Puromycin - pharmacology | Neurons - metabolism | Amyloid beta-Peptides - administration & dosage | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Gene Expression Regulation | Hippocampus - pathology | Mice, Knockout | Stereotaxic Techniques | Hippocampus - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Proto-Oncogene Proteins c-fyn - metabolism | Alzheimer Disease - metabolism | Mice | Alzheimer Disease - genetics | Ribosomal Protein S6 Kinases - genetics | Phosphorylation | Translation | Neurodegenerative diseases | Extracellular signal-regulated kinase | Protein biosynthesis | Activation | Pharmacology | Agglomeration | Kinases | Accumulation | Proteins | Signal transduction | Signaling | Detachment | Clonal deletion | Tau protein | Protein synthesis | Microtubules | Deletion | β-Amyloid | Transduction | Alzheimers disease | Alzheimer's disease | Fyn protein | Index Medicus | Neuroscience | Protein Biosynthesis & Quality Control
Journal Article
Journal Article