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Blood, ISSN 0006-4971, 2009, Volume 113, Issue 26, pp. 6511 - 6521
Journal Article
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 01/2008, Volume 99, Issue 1, pp. 4 - 13
Summary Idiopathic thrombocytopenic purpura (ITP) is characterized by a low platelet count, which is the result of both increased platelet destruction and... 
Thrombocytopenia | Platelet immunology | immunity | Review Article | Immunity | FC-GAMMA RECEPTORS | thrombocytopenia | platelet immunology | COMMON VARIABLE IMMUNODEFICIENCY | HIGH-DOSE DEXAMETHASONE | AUTOIMMUNE THROMBOCYTOPENIA | IN-VITRO | ANTI-CD20 MONOCLONAL-ANTIBODY | INTRAVENOUS IMMUNOGLOBULIN-G | CIRCULATING THROMBOPOIETIN | AUTOREACTIVE T-CELLS | IMMUNE THROMBOCYTOPENIA | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Glucocorticoids - therapeutic use | Pyrazoles - therapeutic use | Benzoates - therapeutic use | Blood Platelets - immunology | Autoantibodies - blood | Humans | Recombinant Fusion Proteins | Thrombopoietin | Purpura, Thrombocytopenic, Idiopathic - blood | Receptors, Fc - therapeutic use | Splenectomy | Purpura, Thrombocytopenic, Idiopathic - therapy | Purpura, Thrombocytopenic, Idiopathic - immunology | T-Lymphocytes - drug effects | Treatment Failure | Blood Platelets - drug effects | Carrier Proteins - therapeutic use | Thrombopoiesis - drug effects | Hematologic Agents - pharmacology | Immune Tolerance - drug effects | Purpura, Thrombocytopenic, Idiopathic - physiopathology | Hydrazines - therapeutic use | Hematologic Agents - therapeutic use | B-Lymphocytes - drug effects | Animals | Platelet Count | Immunoglobulins, Intravenous - therapeutic use | Cell Communication - drug effects | Immunologic Factors - pharmacology | Immunologic Factors - therapeutic use
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 05/2014, Volume 176, Issue 2, pp. 291 - 300
Immune thrombocytopenic purpura ( ITP ) is acquired autoimmune disease in children characterized by the breakdown of immune tolerance. This work is designed to... 
cells | ITP | Th1 | reg | and | Th2 | NK cells | Th1 and Th2 cells | RHEUMATOID-ARTHRITIS | NATURAL-KILLER-CELLS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | LYMPHOCYTE SUBSETS | Treg | PERIPHERAL-BLOOD | IMMUNOLOGY | DISEASE-ACTIVITY | MULTIPLE-SCLEROSIS | PEDIATRIC-PATIENTS | REGULATORY T-CELLS | MONOCLONAL-ANTIBODIES | T-Lymphocyte Subsets - immunology | Humans | Tumor Necrosis Factor-alpha - blood | Child, Preschool | Interleukin-10 - blood | Infant | Male | Th2 Cells - immunology | Th1 Cells - immunology | Purpura, Thrombocytopenic, Idiopathic - blood | Th1 Cells - metabolism | Flow Cytometry | Interleukin-6 - blood | Purpura, Thrombocytopenic, Idiopathic - immunology | Tumor Necrosis Factor-alpha - immunology | B-Lymphocyte Subsets - immunology | Female | Interleukin-10 - secretion | Child | Cytokines - blood | Cytokines - immunology | Enzyme-Linked Immunosorbent Assay | Interferon-gamma - secretion | Tumor Necrosis Factor-alpha - secretion | Cytokines - secretion | Interleukin-6 - secretion | Th2 Cells - metabolism | Interleukin-4 - immunology | Interleukin-4 - secretion | Interleukin-4 - blood | B-Lymphocyte Subsets - metabolism | T-Lymphocyte Subsets - metabolism | Interferon-gamma - immunology | Interleukin-6 - immunology | Interleukin-10 - immunology | Interferon-gamma - blood | Thrombocytopenic purpura | Autoimmunity | Cytokines | Original
Journal Article
Nature Medicine, ISSN 1078-8956, 12/2014, Volume 20, Issue 12, pp. 1410 - 1416
The protein cytotoxic T lymphocyte antigen-4 (CTLA-4) is an essential negative regulator of immune responses, and its loss causes fatal autoimmunity in mice.... 
PATHWAYS | MEDICINE, RESEARCH & EXPERIMENTAL | CLINICAL-PICTURE | HOMEOSTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | AUTOIMMUNITY | REGULATORY T-CELLS | GERMLINE MUTATIONS | MICE | BLOCKADE | IMMUNODEFICIENCY | ABATACEPT | Recurrence | Agammaglobulinemia - immunology | Agammaglobulinemia - genetics | Purpura, Thrombocytopenic, Idiopathic - genetics | Exons | Immune System Diseases - genetics | Humans | Middle Aged | Male | Anemia, Hemolytic, Autoimmune - genetics | Mutation, Missense | Respiratory Tract Infections - genetics | T-Lymphocytes, Regulatory - immunology | Autoimmune Diseases - genetics | Young Adult | Purpura, Thrombocytopenic, Idiopathic - immunology | Adult | Female | Endocytosis - genetics | Polyendocrinopathies, Autoimmune - genetics | Child | Endocytosis - immunology | Granuloma - genetics | Autoimmune Diseases - immunology | CTLA-4 Antigen - genetics | B7-1 Antigen - metabolism | Codon, Nonsense | CTLA-4 Antigen - immunology | Syndrome | Polyendocrinopathies, Autoimmune - immunology | Lung Diseases, Interstitial - immunology | Animals | B-Lymphocytes - immunology | Lung Diseases, Interstitial - genetics | Pedigree | Anemia, Hemolytic, Autoimmune - immunology | Adolescent | Respiratory Tract Infections - immunology | Granuloma - immunology | Heterozygote | Mice | Antigens | Gene mutations | Physiological aspects | Genetic aspects | Immunologic diseases | Research | Risk factors | Proteins | Homeostasis | Cytotoxicity | Ligands | T cell receptors | Mutation | Immune system
Journal Article
Blood, ISSN 0006-4971, 03/2009, Volume 113, Issue 11, pp. 2568 - 2577
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2003, Volume 9, Issue 9, pp. 1123 - 1124
Journal Article
The Oncologist, ISSN 1083-7159, 01/2009, Volume 14, Issue 1, pp. 12 - 21
Journal Article
Journal Article