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1. Full Text Utility of ADAMTS13 Assays in Diagnosing Thrombotic Thrombocytopenic Purpura Reply
by Barrows, BD and Teruya, J
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, ISSN 0003-9985, 04/2015, Volume 139, Issue 4, pp. 433 - 434
MEDICINE, RESEARCH & EXPERIMENTAL | COMPLEMENT | HEMOLYTIC-UREMIC SYNDROME | MEDICAL LABORATORY TECHNOLOGY | PATHOLOGY | Purpura, Thrombotic Thrombocytopenic - enzymology | Purpura, Thrombotic Thrombocytopenic - diagnosis | Humans | ADAM Proteins - blood
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2. Full Text Utility of ADAMTS13 assays in diagnosing thrombotic thrombocytopenic purpura
by Lehman, Christopher M and Rodgers, George M
Archives of Pathology and Laboratory Medicine, ISSN 0003-9985, 04/2015, Volume 139, Issue 4, pp. 433 - 433
MEDICINE, RESEARCH & EXPERIMENTAL | MEDICAL LABORATORY TECHNOLOGY | PATHOLOGY | Purpura, Thrombotic Thrombocytopenic - enzymology | Purpura, Thrombotic Thrombocytopenic - diagnosis | Humans | ADAM Proteins - blood | Thrombocytopenic purpura | Index Medicus | Abridged Index Medicus
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3. Full Text Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies
by Scully, Marie and Hunt, Beverley J and Benjamin, Sylvia and Liesner, Ri and Rose, Peter and Peyvandi, Flora and Cheung, Betty and Machin, Samuel J and British Comm Stand Haematology and British Committee for Standards in Haematology and on behalf of British Committee for Standards in Haematology
British Journal of Haematology, ISSN 0007-1048, 08/2012, Volume 158, Issue 3, pp. 323 - 335
guidelines | thrombotic thrombocytopenic purpura | thrombotic microangiopathy | Thrombotic microangiopathy | Thrombotic thrombocytopenic purpura | Guidelines | ULTRAVIOLET-A-LIGHT | DEFICIENT ACTIVITY | HEMOLYTIC-UREMIC SYNDROME | ANTI-ADAMTS13 ANTIBODIES | VON-WILLEBRAND-FACTOR | FACTOR-CLEAVING PROTEASE | ADAMTS13 ACTIVITY | UK TTP REGISTRY | HEMATOLOGY | FRESH-FROZEN PLASMA | UPSHAW-SCHULMAN SYNDROME | Pregnancy | Diagnosis, Differential | Purpura, Thrombotic Thrombocytopenic - pathology | Thrombotic Microangiopathies - pathology | Humans | Thrombotic Microangiopathies - therapy | Female | Male | Thrombotic Microangiopathies - diagnosis | Purpura, Thrombotic Thrombocytopenic - therapy | Purpura, Thrombotic Thrombocytopenic - diagnosis | Thrombocytopenic purpura | Practice guidelines (Medicine) | Care and treatment | Diagnosis
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4. Full Text Thrombotic thrombocytopenic purpura: From diagnosis to therapy
by Mariotte, Eric and Veyradier, Agnès
Current Opinion in Critical Care, ISSN 1070-5295, 2015, Volume 21, Issue 6, pp. 593 - 601
Purpose of review Thrombotic thrombocytopenic purpura (TTP) is a rare but challenging disease for intensive care specialists. Patients with acute TTP... 
Rituximab | Thrombotic microangiopathy | Thrombotic thrombocytopenic purpura | ADAMTS13 | Plasmapheresis | MANAGEMENT | PLATELET TRANSFUSION | ANTI-ADAMTS13 ANTIBODIES | thrombotic thrombocytopenic purpura | MICROANGIOPATHIES | PLASMA-EXCHANGE | ADAMTS13 ACTIVITY | plasmapheresis | OKLAHOMA REGISTRY | EXPERIENCE | thrombotic microangiopathy | rituximab | UREMIC SYNDROME | CRITICAL CARE MEDICINE | ADAM Proteins - immunology | Intensive Care Units | Age Factors | Comorbidity | Humans | ADAM Proteins - deficiency | Critical Illness | Antibodies, Monoclonal - therapeutic use | Plasma Exchange | Purpura, Thrombotic Thrombocytopenic - complications | Purpura, Thrombotic Thrombocytopenic - diagnosis | ADAMTS13 Protein | Rituximab - therapeutic use | Purpura, Thrombotic Thrombocytopenic - therapy
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5. Full Text Syndromes of Thrombotic Microangiopathy
by George, James N and Nester, Carla M
The New England Journal of Medicine, ISSN 0028-4793, 08/2014, Volume 371, Issue 7, pp. 654 - 666
This review article covers the diverse pathophysiological pathways that can lead to microangiopathic hemolytic anemia and a procoagulant state with or without... 
INDUCED IMMUNE THROMBOCYTOPENIA | MEDICINE, GENERAL & INTERNAL | ESCHERICHIA-COLI | TERM-FOLLOW-UP | ADAMTS13 DEFICIENCY | HEMOLYTIC-UREMIC-SYNDROME | ADAMTS13-DEFICIENT MICE | CLINICAL-FEATURES | SHIGA-TOXIN | VON-WILLEBRAND-FACTOR | UPSHAW-SCHULMAN SYNDROME | Thrombotic Microangiopathies - therapy | Thrombotic Microangiopathies - diagnosis | Purpura, Thrombotic Thrombocytopenic - therapy | Purpura, Thrombotic Thrombocytopenic - diagnosis | Thrombotic Microangiopathies - etiology | Humans | Development and progression | Research | Thrombosis | Blood clot | Risk factors | Blood vessels | Thrombotic microangiopathy | Hemolytic anemia | Mutation | Drug therapy
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6. An update on pathogenesis and diagnosis of thrombotic thrombocytopenic purpura
by Joly, BS and Coppo, P and Veyradier, A
EXPERT REVIEW OF HEMATOLOGY, ISSN 1747-4086, 06/2019, Volume 12, Issue 6, pp. 383 - 395
Introduction: Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic... 
MOLECULAR CHARACTERIZATION | Thrombotic microangiopathy | rare disease | SEVERE ADAMTS13 DEFICIENCY | FACTOR-VIII | ANTI-ADAMTS13 ANTIBODIES | thrombotic thrombocytopenic purpura | VON-WILLEBRAND-FACTOR | FACTOR-CLEAVING PROTEASE | CONFORMATIONAL ACTIVATION | PLASMA-EXCHANGE | ADAMTS13 | autoimmunity | von Willebrand factor | FRENCH NATIONAL REGISTRY | HEMATOLOGY | UPSHAW-SCHULMAN SYNDROME
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7. Full Text How I treat patients with thrombotic thrombocytopenic purpura: 2010
by George, James N
Blood, ISSN 0006-4971, 11/2010, Volume 116, Issue 20, pp. 4060 - 4069
Thrombotic thrombocytopenic purpura (TTP) is the common name for adults with microangiopathic hemolytic anemia, thrombocytopenia, with or without neurologic or... 
INDUCED IMMUNE THROMBOCYTOPENIA | PLASMA-EXCHANGE | SYNDROME TTP-HUS | MICROANGIOPATHY | HEMOLYTIC-UREMIC-SYNDROME | STEM-CELL TRANSPLANTATION | HEMATOLOGY | VON-WILLEBRAND-FACTOR | CONSECUTIVE PATIENTS | FACTOR-CLEAVING PROTEASE | CLINICAL-OUTCOMES | Recurrence | Acute Disease | Adjuvants, Pharmaceutic - pharmacology | Platelet Transfusion | Humans | Risk Factors | Adrenal Cortex Hormones - pharmacology | Treatment Outcome | Purpura, Thrombotic Thrombocytopenic - diagnosis | Adrenal Cortex Hormones - therapeutic use | Cognition - drug effects | ADAMTS13 Protein | Hemolytic-Uremic Syndrome - pathology | ADAM Proteins - metabolism | Purpura, Thrombotic Thrombocytopenic - pathology | Adjuvants, Pharmaceutic - therapeutic use | Purpura, Thrombotic Thrombocytopenic - drug therapy | Registries | Plasma Exchange - adverse effects | Purpura, Thrombotic Thrombocytopenic - therapy | Hemolytic-Uremic Syndrome - drug therapy
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8. Full Text Consensus on the standardization of terminology in thrombotic thrombocytopenic purpura and related thrombotic microangiopathies
by Scully, M and Cataland, S and Coppo, P and Rubia, J and Friedman, K. D and Kremer Hovinga, J and Lämmle, B and Matsumoto, M and Pavenski, K and Sadler, E and Sarode, R and Wu, H and Gale, D and Fujimura, Y and McDonald, V and Peyvandi, F and Scharrer, I and Veyradier, A and Westwood, J. P and Int Working Grp Thrombotic and International Working Group for Thrombotic Thrombocytopenic Purpura and the International Working Group for Thrombotic Thrombocytopenic Purpura
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 02/2017, Volume 15, Issue 2, pp. 312 - 322
Essentials An international collaboration provides a consensus for clinical definitions. This concerns thrombotic microangiopathies and thrombotic... 
diagnosis, differential | thrombotic thrombocytopenic purpura | thrombotic microangiopathy | thrombocytopenia | ADAMTS‐13 protein, human | ADAMTS-13 protein, human | MANAGEMENT | ANTI-ADAMTS13 ANTIBODIES | HEMOLYTIC-UREMIC-SYNDROME | IGG ANTIBODIES | FACTOR-CLEAVING PROTEASE | PLASMA-EXCHANGE | ACUTE EPISODES | ADAMTS13 ACTIVITY | RITUXIMAB | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | UPSHAW-SCHULMAN SYNDROME | Recurrence | Humans | ADAMTS13 Protein - blood | Fibrin - chemistry | Societies, Medical | Adult | Female | Hemolytic-Uremic Syndrome - diagnosis | Child | von Willebrand Factor - metabolism | Hemolysis | Diagnosis, Differential | Hematology - standards | Terminology as Topic | Treatment Outcome | Inflammation | Purpura, Thrombotic Thrombocytopenic - diagnosis | Remission Induction | Consensus | Complement System Proteins | Platelet Aggregation | Pregnancy | Platelet Count | Blood Platelets - metabolism | Erythrocytes - metabolism | Thrombotic Microangiopathies - diagnosis | Thrombocytopenic purpura | Enzymes | Terms and phrases | Anemia | Liver | Von Willebrand factor | Working groups | Standardization | Thrombocytopenia | Thrombotic microangiopathy | Clinical trials | Disseminated intravascular coagulation | Transplantation | Thrombotic thrombocytopenic purpura | Hemolytic anemia | Purpura | Eclampsia | Remission | Platelets | Autoimmune diseases
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9. Full Text The importance of clinical judgment for the diagnosis of thrombotic thrombocytopenic purpura
by George, James N
Transfusion, ISSN 0041-1132, 11/2017, Volume 57, Issue 11, pp. 2558 - 2561
PLASMA-EXCHANGE | HEMOLYTIC-UREMIC SYNDROME | ADAMTS13 ACTIVITY | MICROANGIOPATHIES | HEMATOLOGY | VON-WILLEBRAND-FACTOR | FACTOR-CLEAVING PROTEASE | Thrombocytopenic purpura | Purpura | Thrombotic thrombocytopenic purpura
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10. Full Text External validation of the PLASMIC score: a clinical prediction tool for thrombotic thrombocytopenic purpura diagnosis and treatment
by Li, A and Khalighi, P. R and Wu, Q and Garcia, D. A
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 01/2018, Volume 16, Issue 1, pp. 164 - 169
Essentials Severe ADAMTS‐13 deficiency is key to thrombotic thrombocytopenic purpura (TTP) diagnosis. PLASMIC score predicts ADAMTS‐13 deficiency in suspected... 
platelet count | purpura, thrombotic thrombocytopenic | validation studies | plasma exchange | thrombotic microangiopathies | CALIBRATION | MULTICENTER | TUBES | PROTHROMBIN TIME | INTERNATIONAL SENSITIVITY INDEX | BLOOD COLLECTION SYSTEMS | THROMBOPLASTIN | thrombotic thrombocytopenic | PERIPHERAL VASCULAR DISEASE | RABBIT | HEMATOLOGY | purpura | STANDARD | Thrombocytopenic purpura | Care and treatment | Diagnosis | Thrombocytopenia | Thrombotic microangiopathy | Thrombotic thrombocytopenic purpura | Purpura | Validation Studies | Thrombotic Microangiopathies | Platelet Count | Plasma Exchange | Thrombotic Thrombocytopenic
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11. Full Text Diagnosis of thrombotic thrombocytopenic purpura among patients with ADAMTS13 Activity 10%‐20
by Ayanambakkam, Adanma and Kremer Hovinga, Johanna A and Vesely, Sara K and George, James N
American Journal of Hematology, ISSN 0361-8609, 11/2017, Volume 92, Issue 11, pp. E644 - E646
HEMATOLOGY | MICROANGIOPATHIES
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12. Full Text Thrombotic thrombocytopenic purpura: pathogenesis, diagnosis and potential novel therapeutics
by Saha, M and McDaniel, J. K and Zheng, X. L
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 10/2017, Volume 15, Issue 10, pp. 1889 - 1900
Summary Thrombotic thrombocytopenic purpura (TTP), a potentially fatal clinical syndrome, is primarily caused by autoantibodies against the von Willebrand... 
diagnosis | therapeutics | pathology | thrombotic microangiopathies | von Willebrand factor | HEMOLYTIC-UREMIC-SYNDROME | VON-WILLEBRAND-FACTOR | FACTOR-CLEAVING PROTEASE | MEDIATED GENE-THERAPY | PLASMA-EXCHANGE THERAPY | ADAMTS13 ACTIVITY | DISSEMINATED INTRAVASCULAR COAGULATION | ADVERSE-REACTIONS SONAR | RENAL-FAILURE | PERIPHERAL VASCULAR DISEASE | MALIGNANT HYPERTENSION | HEMATOLOGY | Recombinant Proteins - therapeutic use | Genetic Therapy | Predictive Value of Tests | Autoantibodies - blood | Humans | Plasma Exchange | ADAMTS13 Protein - blood | ADAMTS13 Protein - immunology | Hemostasis | Immunotherapy | Thrombocytopenia - therapy | Diagnosis, Differential | ADAMTS13 Protein - therapeutic use | Risk Factors | Treatment Outcome | Purpura, Thrombotic Thrombocytopenic - diagnosis | Purpura, Thrombotic Thrombocytopenic - epidemiology | Thrombocytopenia - blood | ADAMTS13 Protein - genetics | Anemia, Hemolytic - therapy | Anemia, Hemolytic - diagnosis | Thrombocytopenia - diagnosis | Purpura, Thrombotic Thrombocytopenic - therapy | Anemia, Hemolytic - blood | Purpura, Thrombotic Thrombocytopenic - blood | Autoimmunity | Autoantibodies | Anemia | Development and progression | Homeopathy | Materia medica and therapeutics | Thrombocytopenic purpura | Haptoglobin | Therapeutics | Von Willebrand factor | Hemoglobin | Diagnosis | Health aspects | Corticoids | Plasma | Cyclosporins | Pathogenesis | Prophylaxis | Antagonists | Splenectomy | Hemolytic anemia | Remission | Metalloproteinase | Thrombocytopenia | Thrombotic microangiopathy | Hemolytic uremic syndrome | Immunomodulation | Rituximab | Morbidity | L-Lactate dehydrogenase | Cyclophosphamide | Purpura | Lactic acid | Gene therapy | Platelets | Pathology | Thrombotic Microangiopathies | von Willebrand Factor
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