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British Journal of Cancer, ISSN 0007-0920, 09/2013, Volume 109, Issue 5, pp. 1252 - 1263
Background: Our previous study revealed that proline-rich tyrosine kinase 2 (Pyk2) is implicated in both anchorage-independent growth and anoikis resistance in... 
cancer stem cell; immunohistochemistry; non-small-cell lung cancer; phosphorylated Pyk2; prognosis; Pyk2 | EPITHELIAL-MESENCHYMAL TRANSDIFFERENTIATION | STEM-CELLS | ACTIVATED PROTEIN-KINASE | ADENOCARCINOMA | prognosis | GROWTH-FACTOR RECEPTOR | NASOPHARYNGEAL CARCINOMA PROGRESSION | cancer stem cell | ONCOLOGY | Pyk2 | phosphorylated Pyk2 | immunohistochemistry | FOCAL ADHESION KINASE | DIFFERENTIATION | EXPRESSION | non-small-cell lung cancer | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Up-Regulation | Phosphorylation | Humans | Lung Neoplasms - metabolism | Middle Aged | Aldehyde Dehydrogenase - biosynthesis | TYK2 Kinase - metabolism | Male | RNA, Messenger - metabolism | Biomarkers, Tumor | Polycomb Repressive Complex 1 - biosynthesis | Gene Knockdown Techniques | Polycomb Repressive Complex 1 - genetics | ATP-Binding Cassette Transporters - genetics | Aged, 80 and over | Adult | Female | Neoplasm Proteins - genetics | Lung Neoplasms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Neoplasm Proteins - biosynthesis | RNA, Messenger - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Aldehyde Dehydrogenase - genetics | Treatment Outcome | Disease Progression | ATP-Binding Cassette Transporters - biosynthesis | Cell Line, Tumor | Aged | TYK2 Kinase - genetics | Molecular Diagnostics
Journal Article
Experimental Neurology, ISSN 0014-4886, 01/2019, Volume 311, pp. 313 - 317
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is the most common cause of dementia and the 6th leading cause of death. Although... 
NERVOUS-SYSTEM | FAK | ACTIVATION | COMPLEX | PYK2 | GLUTAMATE | PYK2/CAK-BETA | FOCAL ADHESION KINASE | NEUROSCIENCES | CELLULAR PRION PROTEIN | BETA | Tyrosine | Alzheimer's disease | Drug discovery
Journal Article
Experimental Neurology, ISSN 0014-4886, 09/2018, Volume 307, pp. 62 - 73
Pyk2 is a Ca -activated non-receptor tyrosine kinase enriched in forebrain neurons and involved in synaptic regulation. Human genetic studies associated , the... 
Mouse model | Src | Alzheimer's disease | Pyk2 | Non-receptor tyrosine protein kinase | ACTIVATION | PROTEIN-TYROSINE KINASE | NEUROSCIENCES | DEPOLARIZATION | AMYLOID-BETA | CENTRAL-NERVOUS-SYSTEM | PYK2/CAK-BETA | LONG-TERM POTENTIATION | COGNITIVE DEFICITS | Analysis | Index Medicus | Malaltia d'Alzheimer | Protein metabolism | Metabolisme de proteïnes
Journal Article
Amino Acids, ISSN 0939-4451, 2014, Volume 46, Issue 11, pp. 2605 - 2614
Journal Article
Cellular Signalling, ISSN 0898-6568, 01/2020, Volume 65, p. 109434
Muscarinic receptor stimulation or protein kinase C (PKC) activation in rat adrenal medullary and PC12 cells rapidly induces tyrosine phosphorylation of... 
TASK channel | PC12 | Endocytosis | Src | Pyk2 | PKC | Muscarinic receptor
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2019, Volume 35, Issue 6, pp. 868 - 884.e6
Heterotypic interactions across diverse cell types can enable tumor progression and hold the potential to expand therapeutic interventions. Here, combined... 
macrophages | glioblastoma | PYK2 | recruitment | SPP1 and YAP1 | PTEN | lysyl oxidase | Oxidases | Medical colleges | Gliomas | Analysis | Development and progression | Macrophages | Integrins
Journal Article
Experimental Cell Research, ISSN 0014-4827, 10/2019, Volume 383, Issue 2, p. 111555
Osteoclast adhesion is important for bone resorption. Osteoprotegerin inhibits osteoclast differentiation and bone resorption via Ca signaling. Purinergic... 
Osteoclast | Ca2 | Adhesion structure | P2X7R | Osteoprotegerin | SRC | KINASE | SEALING-ZONE | CELL BIOLOGY | ONCOLOGY | PYK2 | RECEPTOR ACTIVATOR | DIFFERENTIATION
Journal Article
Journal of Cell Science, ISSN 0021-9533, 04/2010, Volume 123, Issue 7, pp. 1007 - 1013
Journal Article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, ISSN 1756-9966, 05/2019, Volume 38, Issue 1, pp. 210 - 14
Background: Metformin, a biguanide, is one of the most commonly prescribed treatments for type 2 diabetes and has recently been recommended as a potential drug... 
CELLS | Pure HER2 breast Cancer | PHOSPHORYLATION | Chemoresistance | MARKERS | MECHANISMS | TYROSINE KINASE 2 | ONCOLOGY | PYK2 | PTK2B | Metformin | FOCAL ADHESION KINASE | Breast cancer stem cells | Polymerase chain reaction | Care and treatment | Usage | Breast cancer | Genetic aspects | Research | Gene expression | Proteins | Cell growth | Plasmids | Lung cancer | Stem cells | Systematic review | Diabetes | Kinases | Cancer therapies | Apoptosis | PYK2/PTK2B
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 07/2002, Volume 22, Issue 13, pp. 5452 - 5461
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 03/2006, Volume 6, Issue 3, pp. 173 - 182
Journal Article
Journal of Reproduction and Development, ISSN 0916-8818, 2016
The non-receptor tyrosine kinase Pyk2 is a member of the focal adhesion kinase family and is highly expressed in oocytes. Using a combination of confocal... 
Fertilization | Pyk2 | Mouse oocyte | Early-embryo development
Journal Article