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Pharmacogenetics and Genomics, ISSN 1744-6872, 04/2012, Volume 22, Issue 4, pp. 310 - 318
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 10/2006, Volume 33, Issue 10, pp. 917 - 924
SUMMARY • Non-steroidal anti-inflammatory drugs (NSAIDs) cause renal side-effects. In the present study, we tested the hypothesis that the extent of the renal... 
pharmacokinetics | kidney | non-steroidal anti-inflammatory drugs | cyclo-oxygenase-2 | sodium urinary excretion | cyclo‐oxygenase‐2 | non‐steroidal anti‐inflammatory drugs | Cyclo-oxygenase-2 | Pharmacokinetics | Kidney | Non-steroidal anti-inflammatory drugs | Sodium urinary excretion | GASTROINTESTINAL TOXICITY | PHYSIOLOGY | CYCLOOXYGENASE-2 | RAT | HYPERKALEMIA | PROTEIN-BINDING | MELOXICAM | INTERSPECIES DIFFERENCES | GENTAMICIN | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | PHARMACOLOGY & PHARMACY | Thiazoles - blood | Area Under Curve | Thiazines - administration & dosage | Thiazines - adverse effects | Sulfones - adverse effects | Male | Thiazoles - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - blood | Thiazoles - adverse effects | Thiazoles - pharmacokinetics | Dose-Response Relationship, Drug | Cyclooxygenase 2 Inhibitors - adverse effects | Sulfonamides - blood | Lactones - blood | Lactones - pharmacokinetics | Sodium - urine | Lactones - administration & dosage | Pyrazoles - blood | Pyrazoles - pharmacokinetics | Sulfones - blood | Placebos - administration & dosage | Pyrazoles - adverse effects | Thiazines - pharmacokinetics | Kidney - drug effects | Administration, Oral | Cyclooxygenase 2 Inhibitors - administration & dosage | Rats | Thiazines - blood | Celecoxib | Lactones - adverse effects | Placebos - pharmacokinetics | Sulfones - pharmacokinetics | Cyclooxygenase 2 Inhibitors - pharmacokinetics | Rats, Sprague-Dawley | Sulfonamides - pharmacokinetics | Pyrazoles - administration & dosage | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Potassium - urine | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Sulfonamides - adverse effects | Sulfonamides - administration & dosage | Sulfones - administration & dosage | Kidney, drug effects | Lactones, adverse effects | Sulfones, administration and dosage | Thiazoles, administration and dosage | Anti-Inflammatory Agents, Non-Steroidal, pharmacokinetics | Anti-Inflammatory Agents, Non-Steroidal, adverse effects | Sodium, urine | Thiazines, blood | Anti-Inflammatory Agents, Non-Steroidal, blood | Lactones, administration and dosage | Cyclooxygenase 2 Inhibitors, adverse effects | Pyrazoles, blood | Sulfonamides, pharmacokinetics | Thiazines, pharmacokinetics | Pyrazoles, administration and dosage | Thiazoles, blood | Sulfonamides, administration and dosage | Cyclooxygenase 2 Inhibitors, administration and dosage | Lactones, pharmacokinetics | Sulfonamides, blood | Cyclooxygenase 2 Inhibitors, pharmacokinetics | Thiazines, adverse effects | Lactones, blood | Thiazoles, adverse effects | Thiazoles, pharmacokinetics | Sulfones, blood | Sulfonamides, adverse effects | Thiazines, administration and dosage | Placebos, pharmacokinetics | Sulfones, pharmacokinetics | Pyrazoles, adverse effects | Placebos, administration and dosage | Potassium, urine | Sulfones, adverse effects | Pyrazoles, pharmacokinetics | Index Medicus
Journal Article
Journal Article
Analytical and Bioanalytical Chemistry, ISSN 1618-2642, 4/2018, Volume 410, Issue 11, pp. 2815 - 2828
Generation of skin distribution profiles and reliable determination of drug molecule concentration in the target region are crucial during the development... 
Biochemistry, general | Skin penetration | Food Science | Quantification | Drug distribution | Mass spectrometry imaging | Human skin | Laboratory Medicine | MALDI-MSI | Chemistry | Analytical Chemistry | Monitoring/Environmental Analysis | Characterization and Evaluation of Materials | CHEMISTRY, ANALYTICAL | HUMAN STRATUM-CORNEUM | BIOCHEMICAL RESEARCH METHODS | PENETRATION | MOLECULAR-SIZE | MICROSCOPY | MASS-SPECTROMETRY | TISSUE-SECTIONS | ATOPIC-DERMATITIS | PERCUTANEOUS-ABSORPTION | PSORIASIS | Pyrroles - pharmacokinetics | Benzamides - pharmacokinetics | Skin - metabolism | Humans | Aminopyridines - pharmacokinetics | Pyridines - pharmacokinetics | Drug Discovery - methods | Benzamides - administration & dosage | Cyclopropanes - administration & dosage | Phosphodiesterase 4 Inhibitors - administration & dosage | Pyrroles - administration & dosage | Piperidines - pharmacokinetics | Pyrazoles - pharmacokinetics | Cyclopropanes - pharmacokinetics | Protein Kinase Inhibitors - pharmacokinetics | Aminopyridines - administration & dosage | Piperidines - administration & dosage | Pyridines - administration & dosage | Acetamides - pharmacokinetics | Phosphodiesterase 4 Inhibitors - pharmacokinetics | Pyrimidines - administration & dosage | Skin Absorption | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Pyrimidines - pharmacokinetics | Administration, Topical | Acetamides - administration & dosage | Pharmaceutical research | Topical medication | Pharmaceutical industry | Innovations | Testing | Formulations | Explants | Psoriasis | Medical treatment | Spatial discrimination | Imaging techniques | Ions | Mass spectroscopy | Desorption | Drug development | Tissues | Dermatitis | Ionization | Lasers | Atopic dermatitis | Imaging | Skin diseases | Skin | Mass spectrometry | Spatial resolution | Physicochemical properties | Index Medicus
Journal Article
British Journal of Surgery, ISSN 0007-1323, 06/2014, Volume 101, Issue 7, pp. 742 - 749
Journal Article
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 11/2013, Volume 76, Issue 5, pp. 776 - 786
Journal Article