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Cochrane Database of Systematic Reviews, ISSN 1469-493X, 01/2018, Volume 2018, Issue 1, p. CD009669
Journal Article
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 2017, Volume 24, Issue 16, pp. 1 - 16
The old-fashioned anticancer approaches, aiming at arresting cancer cell proliferation interfering with non-specific targets (e.g. DNA), have been replaced, in... 
Tumor microenvironment | Fda-Approved drugs | Multitargeted drugs | Anticancer agents | Polypharmacology | Tyrosine kinase receptors | Oncogene addiction | CHRONIC MYELOGENOUS LEUKEMIA | CHEMISTRY, MEDICINAL | GROWTH-FACTOR-RECEPTOR | TARGETED-THERAPY | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | REGORAFENIB BAY 73-4506 | BCR-ABL INHIBITOR | anticancer agents | FDA-approved drugs | CELL LUNG-CANCER | tyrosine kinase receptors | oncogene addiction | polypharmacology | PHILADELPHIA-CHROMOSOME | COLORECTAL-CANCER | PHARMACOLOGY & PHARMACY | tumor microenvironment | GASTROINTESTINAL STROMAL TUMORS | Neoplasms - metabolism | Niacinamide - analogs & derivatives | Anilides - therapeutic use | Pyrazoles - therapeutic use | Pyridines - chemistry | Humans | Anilides - chemistry | Imidazoles - chemistry | Imatinib Mesylate - therapeutic use | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Niacinamide - chemistry | Phenylurea Compounds - chemistry | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Imidazoles - therapeutic use | Pyrroles - therapeutic use | Quinazolines - chemistry | Pyridazines - therapeutic use | Pyridines - therapeutic use | Piperidines - chemistry | Niacinamide - therapeutic use | Phenylurea Compounds - therapeutic use | Receptor Protein-Tyrosine Kinases - metabolism | Imatinib Mesylate - chemistry | Neoplasms - drug therapy | Pyridazines - chemistry | Piperidines - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Pyrroles - chemistry | Indoles - therapeutic use | Neoplasms - pathology | Indoles - chemistry | Tyrosine | Cell proliferation | Drugs | Medical research | Phenotypes | Clinical trials | Kinases | Proteins | Inhibitors | Modulation | Protein-tyrosine kinase | Deoxyribonucleic acid--DNA | Cancer
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2015, Volume 373, Issue 9, pp. 834 - 844
Patients with previously untreated pulmonary arterial hypertension who were randomly assigned to combination therapy with ambrisentan and tadalafil had a... 
INHALED ILOPROST | SURVIVAL | TRIAL | DIAGNOSIS | MEDICINE, GENERAL & INTERNAL | EPOPROSTENOL | COMBINATION THERAPY | HEART-FAILURE | DOUBLE-BLIND | BOSENTAN | Hypertension, Pulmonary - mortality | Double-Blind Method | Humans | Middle Aged | Risk Factors | Kaplan-Meier Estimate | Hypertension, Pulmonary - physiopathology | Male | Hospitalization | Disease Progression | Tadalafil | Phenylpropionates - therapeutic use | Peptide Fragments - blood | Adult | Female | Phenylpropionates - adverse effects | Aged | Hypertension, Pulmonary - drug therapy | Drug Therapy, Combination | Carbolines - therapeutic use | Carbolines - adverse effects | Natriuretic Peptide, Brain - blood | Pyridazines - adverse effects | Pyridazines - therapeutic use | Symptomatology | Care and treatment | Usage | Analysis | Clinical trials | Dosage and administration | Pulmonary hypertension | Ambrisentan | Hypertension | Edema | Brain natriuretic peptide | Headache | Functional morphology | Pulmonary arteries | Lung diseases | Drug therapy | Patients | Clinical outcomes | Drug side effects | Assaigs clínics de medicaments | Efectes secundaris dels medicaments | Hipertensió pulmonar | Drug testing | Life Sciences | Human health and pathology | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2014, Volume 171, Issue 24, pp. 5555 - 5572
Journal Article
Journal Article