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Journal of clinical oncology, ISSN 0732-183X, 11/2012, Volume 30, Issue 32, pp. 4017 - 4025
.... Perhaps the most important obstacle is the impractical requirement of multiple blood samples to adequately define systemic exposure of drugs that have a short elimination half-life and are given... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplasms - metabolism | Niacinamide - analogs & derivatives | Piperazines - administration & dosage | Thiazoles - blood | Injections, Intravenous | Area Under Curve | Pyrimidines - blood | Humans | Antibodies, Monoclonal, Murine-Derived - administration & dosage | Half-Life | Thiazoles - administration & dosage | Phenylurea Compounds | Antineoplastic Agents - administration & dosage | Benzenesulfonates - administration & dosage | Drug Monitoring - methods | Indoles - administration & dosage | Antibodies, Monoclonal - blood | Antibodies, Monoclonal, Humanized | Neoplasms - blood | Antineoplastic Agents - adverse effects | Pyrroles - administration & dosage | Benzenesulfonates - blood | Antineoplastic Agents - pharmacokinetics | Cetuximab | Piperazines - blood | Everolimus | Molecular Targeted Therapy - methods | Dasatinib | Sirolimus - analogs & derivatives | Pyridines - administration & dosage | Pyrimidines - administration & dosage | Indoles - blood | Rituximab | Pyrroles - blood | Sirolimus - blood | Evidence-Based Medicine | Imatinib Mesylate | Neoplasms - drug therapy | Sirolimus - administration & dosage | Antibodies, Monoclonal, Murine-Derived - blood | Pyridines - blood | Animals | Antibodies, Monoclonal - administration & dosage | Antineoplastic Agents - blood | Benzamides | Index Medicus
Journal Article
International journal of legal medicine, ISSN 0937-9827, 1/2016, Volume 130, Issue 1, pp. 179 - 183
Journal Article
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 09/2010, Volume 104, Issue 3, pp. 633 - 641
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2013, Volume 31, Issue 4, pp. 412 - 419
Journal Article
Journal Article
Pharmaceutical research, ISSN 1573-904X, 11/2018, Volume 36, Issue 1, pp. 1 - 8
...) at the mouse blood-brain barrier (BBB) as well as Lat1 function and expression in mouse primary... 
Biochemistry, general | alzheimer’s disease | blood-brain barrier | L-type amino acid transporter | Biomedicine | Pharmacy | Medical Law | Pharmacology/Toxicology | Biomedical Engineering and Bioengineering | CNS drug delivery | Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Lipopolysaccharides - toxicity | Large Neutral Amino Acid-Transporter 1 - metabolism | Mice, Inbred C57BL | Astrocytes - pathology | Encephalitis - pathology | Presenilin-1 - genetics | Mice, Transgenic | Imidazoles - pharmacology | RNA, Messenger - metabolism | Blood-Brain Barrier - drug effects | Alzheimer Disease - pathology | Blood-Brain Barrier - metabolism | Blood-Brain Barrier - pathology | Amyloid beta-Protein Precursor - genetics | Animals | Mice | Pyridines - pharmacology | Encephalitis - chemically induced | Large Neutral Amino Acid-Transporter 1 - physiology | Mutation | Primary Cell Culture | Alzheimer Disease - genetics | Astrocytes - metabolism | Disease Models, Animal | Drugs | Drug delivery systems | RNA | Amino acids | Genetic aspects | Genetic engineering | Alzheimer's disease | Mitogens | Central nervous system agents | Vehicles | L-leucine | mRNA | Leucine | LAT1 protein | Lipopolysaccharides | Proteins | Blood-brain barrier | Protein folding | Rodents | Carbon 14 | Significance | Phenotypes | Statistical analysis | Astrocytes | Transgenic mice | Gene expression | Acids | Perfusion | Presenilin 1 | Protein expression | Transporter | Index Medicus | Research Paper
Journal Article
The lancet oncology, ISSN 1470-2045, 08/2015, Volume 16, Issue 8, pp. 937 - 948
Summary Background Tumour mutational status is an important determinant of the response of metastatic colorectal cancer to targeted treatments. However, the... 
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Predictive Value of Tests | Proto-Oncogene Proteins p21(ras) | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Clinical Trials, Phase III as Topic | Time Factors | DNA Mutational Analysis | Colorectal Neoplasms - drug therapy | Real-Time Polymerase Chain Reaction | Precision Medicine | Receptor, TIE-1 - blood | Phosphatidylinositol 3-Kinases - blood | Genetic Predisposition to Disease | Adenocarcinoma - blood | ras Proteins - blood | Adenocarcinoma - drug therapy | Adenocarcinoma - secondary | Disease Progression | Phenotype | Class I Phosphatidylinositol 3-Kinases | Biomarkers, Tumor - genetics | ras Proteins - genetics | Patient Selection | DNA, Neoplasm - blood | Female | Adenocarcinoma - genetics | Retrospective Studies | Pyridines - therapeutic use | Colorectal Neoplasms - mortality | Colorectal Neoplasms - blood | Kaplan-Meier Estimate | Proportional Hazards Models | Phenylurea Compounds - therapeutic use | Proto-Oncogene Proteins B-raf - blood | Proto-Oncogene Proteins - genetics | Treatment Outcome | Randomized Controlled Trials as Topic | Biomarkers, Tumor - blood | Phosphatidylinositol 3-Kinases - genetics | Disease-Free Survival | Proto-Oncogene Proteins B-raf - genetics | Aged | DNA, Neoplasm - genetics | Colorectal Neoplasms - pathology | Proto-Oncogene Proteins - blood | Adenocarcinoma - mortality | Medical colleges | Medical research | Cancer patients | Prognosis | Liver | DNA | Colorectal cancer | Genetic research | Medicine, Experimental | Metastasis | Index Medicus | Life Sciences | Human health and pathology
Journal Article