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The New England Journal of Medicine, ISSN 0028-4793, 03/2016, Volume 374, Issue 10, pp. 928 - 939
Journal Article
Malaria Journal, ISSN 1475-2875, 07/2014, Volume 13, Issue 1, pp. 284 - 284
Background: Anti-malarial drug resistance in Plasmodium falciparum in India has historically travelled from northeast India along the Myanmar border. The... 
Plasmodium falciparum | Dihydrofolate reductase (dhfr) | Artesunate + sulphadoxine-pyrimethamine (AS + SP) | Artemisinin combination therapy (ACT) | Dihyropteroate synthase (dhps) | MUTANT | INFECTIOUS DISEASES | PREVALENCE | TROPICAL MEDICINE | CAMBODIA | PRESCRIPTION PRACTICES | Artesunate plus sulphadoxine-pyrimethamine (AS plus SP) | IN-VIVO | GENES | MALARIA | PROVINCE | RESISTANT PLASMODIUM-FALCIPARUM | PARASITOLOGY | Humans | Child, Preschool | Sulfadoxine - administration & dosage | Male | Pyrimethamine - pharmacology | Plasmodium falciparum - drug effects | Artemisinins - pharmacology | Malaria, Falciparum - mortality | Pyrimethamine - administration & dosage | Sulfadoxine - therapeutic use | Treatment Failure | Malaria, Falciparum - epidemiology | Adult | Female | Drug Therapy, Combination | Child | Pyrimethamine - therapeutic use | Malaria, Falciparum - drug therapy | Sulfadoxine - pharmacology | Risk Factors | Kaplan-Meier Estimate | Artemisinins - administration & dosage | India - epidemiology | Antimalarials - therapeutic use | Antimalarials - pharmacology | Malaria, Falciparum - parasitology | Artemisinins - therapeutic use | Antimalarials - administration & dosage | Adolescent | Drug Combinations | Malaria | Analysis | Studies | Mosquitoes | Erythrocytes | Monitoring systems | Parasites | Dihydrofolate reductase | Boundaries | Drug resistance
Journal Article
Annals of Neurology, ISSN 0364-5134, 06/2017, Volume 81, Issue 6, pp. 837 - 848
Objective Cu/Zn superoxide dismutase (SOD1) reduction prolongs survival in SOD1‐transgenic animal models. Pyrimethamine produces dose‐dependent SOD1 reduction... 
SURVIVAL | TRIAL | PILOT | ANTISENSE OLIGONUCLEOTIDE THERAPY | QUALITY-OF-LIFE | ALS PATIENTS | MODEL | NATURAL-HISTORY | PROTEINS | BINDING | NEUROSCIENCES | CLINICAL NEUROLOGY | Humans | Middle Aged | Male | Superoxide Dismutase-1 - cerebrospinal fluid | Pyrimethamine - pharmacology | Amyotrophic Lateral Sclerosis - drug therapy | Superoxide Dismutase-1 - drug effects | Young Adult | Folic Acid Antagonists - cerebrospinal fluid | Amyotrophic Lateral Sclerosis - cerebrospinal fluid | Adult | Female | Folic Acid Antagonists - adverse effects | Severity of Illness Index | Pyrimethamine - adverse effects | Amyotrophic Lateral Sclerosis - genetics | Treatment Outcome | Amyotrophic Lateral Sclerosis - blood | Pyrimethamine - blood | Superoxide Dismutase-1 - genetics | Folic Acid Antagonists - blood | Pyrimethamine - cerebrospinal fluid | Aged | Mutation | Folic Acid Antagonists - pharmacology | Cell culture | Animal models | Erythrocytes | Superoxide dismutase | Cerebrospinal fluid | Leukocytes | Motor task performance | Functional anatomy | Transgenic animals | Colony-stimulating factor | Safety | Copper | Cell survival | Effectiveness | Pyrimethamine | Amyotrophic lateral sclerosis | Superoxide | Assessments | Survival | Patients | Zinc | Quality of life | Screening | Strength | Basic Medicine | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Neurovetenskaper
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e58019
Journal Article
Clinical Therapeutics, ISSN 0149-2918, 2012, Volume 34, Issue 11, pp. 2212 - 2220
Abstract Background Sulfadoxine/pyrimethamine fixed-dose combination (FDC) tablet is the long-acting portion of the antimalaria product Artecospe® , coblister... 
Internal Medicine | Medical Education | parallel design | sulfadoxine | pharmacokinetic | LC-IDMS | bioequivalence | pyrimethamine | WESTERN KENYA | INTERMITTENT PREVENTIVE TREATMENT | FALCIPARUM-MALARIA | SULFADOXINE-PYRIMETHAMINE | PHARMACOLOGY & PHARMACY | PREGNANCY | Tablets | Sulfadoxine - blood | Humans | Middle Aged | Antimalarials - blood | Sulfadoxine - administration & dosage | Male | Sulfadoxine - chemistry | Drugs, Generic - chemistry | Sulfadoxine - adverse effects | Sulfadoxine - pharmacokinetics | Young Adult | Drugs, Generic - pharmacokinetics | Pyrimethamine - administration & dosage | China | Mass Spectrometry | Chromatography, Liquid | Adult | Indicator Dilution Techniques | Pyrimethamine - chemistry | Antimalarials - adverse effects | Antimalarials - pharmacokinetics | Pyrimethamine - adverse effects | Administration, Oral | Drugs, Generic - administration & dosage | Linear Models | Chi-Square Distribution | Pyrimethamine - pharmacokinetics | Chemistry, Pharmaceutical | Drugs, Generic - adverse effects | Asian Continental Ancestry Group | Analysis of Variance | Antimalarials - administration & dosage | Pyrimethamine - blood | Models, Biological | Adolescent | Antimalarials - chemistry | Drug Combinations | Therapeutic Equivalency | Antimalarials | Dosage and administration | Drug therapy, Combination | Public health | Hepatitis | Hospitals | Malaria | Parasites | Dihydrofolate reductase | Drug therapy | Drug dosages
Journal Article
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN 1469-493X, 2018, Volume 11, Issue 11, p. CD011444
Background The World Health Organization recommends intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine for malaria for all... 
Abortion, Spontaneous [chemically induced; epidemiology] | HIV Infections [complications] | ANTIMALARIAL AGENTS | Africa South of the Sahara [epidemiology] | EFFICACY | LOW-BIRTH-WEIGHT | Humans | Trimethoprim | SULFADOXINE-PYRIMETHAMINE RESISTANCE | Thailand [epidemiology] | PROPHYLAXIS | MEDICINE, GENERAL & INTERNAL | Insecticide-Treated Bednets | Parasitemia [epidemiology] | Combination | PLASMODIUM-FALCIPARUM | INFANTS | Female | INFECTION | Pregnancy Complications, Parasitic [epidemiology; prevention & control] | Infant, Low Birth Weight | Mefloquine [adverse effects; therapeutic use] | Drug Therapy | RISK | Antimalarials [adverse effects; therapeutic use] | Dizziness [chemically induced; epidemiology] | Randomized Controlled Trials as Topic | Sulfadoxine [adverse effects; therapeutic use] | Pregnancy | Malaria [epidemiology; prevention & control] | HIV | Vomiting [chemically induced; epidemiology] | Sulfamethoxazole Drug Combination [therapeutic use] | Drug Combinations | Pyrimethamine [adverse effects; therapeutic use] | Pyrimethamine - therapeutic use | Antimalarials - adverse effects | HIV Seronegativity | Placenta Diseases - epidemiology | Anemia - epidemiology | Pregnancy Complications, Infectious - epidemiology | Stillbirth | Antimalarials - therapeutic use | Parasitemia - drug therapy | Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use | Placenta Diseases - parasitology | Mefloquine - adverse effects | Malaria - prevention & control | Vomiting - chemically induced | Mefloquine - therapeutic use | Sulfadoxine - therapeutic use | Pregnancy Complications, Infectious - prevention & control | Pregnancy Complications - chemically induced | Drug Therapy, Combination
Journal Article
Malaria Journal, ISSN 1475-2875, 04/2017, Volume 16, Issue 1, pp. 163 - 6
Journal Article
Malaria Journal, ISSN 1475-2875, 07/2014, Volume 13, Issue 1, pp. 274 - 274
Background: Malaria during pregnancy results in adverse outcomes for mothers and infants. Intermittent preventive treatment (IPT) with... 
Sulphadoxine-pyrimethamine resistance | Sulphadoxine-pyrimethamine intermittent preventive treatment | Malaria in pregnancy | Placental malaria | Submicroscopic infection | PLASMODIUM-FALCIPARUM INFECTIONS | INFECTIOUS DISEASES | LOW-BIRTH-WEIGHT | MICROSCOPY | TROPICAL MEDICINE | REAL-TIME PCR | GENOTYPES | WOMEN | AFRICA | BURDEN | PARASITOLOGY | Prevalence | Follow-Up Studies | Parasitemia - diagnosis | Humans | Fetal Diseases - prevention & control | Fluorenes - therapeutic use | Malawi - epidemiology | Sulfadoxine - administration & dosage | Parasitemia - drug therapy | Plasmodium - drug effects | Pyrimethamine - pharmacology | Asymptomatic Diseases | Quinine - therapeutic use | Pyrimethamine - administration & dosage | Sulfadoxine - therapeutic use | Polymerase Chain Reaction | Pregnancy Complications, Infectious - prevention & control | Adult | Female | Malaria - transmission | Pregnancy Trimesters | DNA, Protozoan - blood | Drug Resistance | Infant, Newborn | Pyrimethamine - therapeutic use | Drug Administration Schedule | Sulfadoxine - pharmacology | Plasmodium - genetics | Malaria - embryology | False Negative Reactions | Malaria - diagnosis | Antimalarials - therapeutic use | Plasmodium - isolation & purification | Antimalarials - pharmacology | Malaria - prevention & control | Pregnancy | Artemisinins - therapeutic use | Antimalarials - administration & dosage | Parasitemia - prevention & control | Pregnancy Complications, Infectious - drug therapy | Ethanolamines - therapeutic use | Hemeproteins - analysis | Malaria - drug therapy | Placenta - parasitology | Erythrocytes - parasitology | Infectious Disease Transmission, Vertical - prevention & control | Drug Combinations | Pregnancy Outcome | Medicine, Experimental | Medical research | Infants | Malaria | Menstruation | Infections | Prenatal care | Medicine | Studies | Polymerase chain reaction | Chemotherapy | Histopathology | Microscopy | Womens health | Biopsy | Birth weight | Osteopathic medicine | Age
Journal Article
PLoS medicine, ISSN 1549-1277, 2009, Volume 6, Issue 4, p. e1000055
Journal Article