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Biophysical Journal, ISSN 0006-3495, 02/2017, Volume 112, Issue 3, pp. 276a - 276a
Journal Article
1970, Chemistry of heterocyclic compounds, Volume 16, v.
Book
Biosensors & bioelectronics, ISSN 0956-5663, 05/2019, Volume 132, p. 186
In this study, a signal-on nanobiosensor based on bivalent aptamer-Cu nanocluster was designed and optimized for specific and sensitive detection of... 
Pyrimidines
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 2008, Volume 16, Issue 12, pp. 6344 - 6352
A series of pyrazolo[1,5- a]pyrimidine, triazolo[1,5- a]pyrimidine, and pyrimido[1,2- a]benzimidazole ring systems incorporating phenylsulfonyl moiety were... 
Pyrazolo[1,5- a]pyrimidine | Analgesic | Phenylsulfonylpyrazole | Pyrimido[1,2- a]benzimidazole | Structure–activity relationship (SAR) | Anti-inflammatory | Triazolo[1,5- a]pyrimidine | Structure-activity relationship (SAR) | Triazolo[1,5-a]pyrimidine | Pyrazolo[1,5-a]pyrimidine | Pyrimido[1,2-a]benzimidazole | pyrazolo[1,5-a] pyrimidine | CHEMISTRY, MEDICINAL | ACID | EFFICACY | analgesic | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | CELECOXIB | IBUPROFEN | pyrimido[1,2-a] benzimidazole | ANTIMICROBIAL EVALUATION | anti-inflammatory | REGIOSELECTIVE SYNTHESIS | INHIBITORS | OSTEOARTHRITIS | 1,3,4-OXA(THIA)DIAZOLE | phenylsulfonylpyrazole | triazolo[1,5-a] pyrimidine | Analgesics - pharmacology | Pyrimidines - chemical synthesis | Benzimidazoles - chemical synthesis | Rats | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Structure-Activity Relationship | Pyrimidines - pharmacology | Benzimidazoles - chemistry | Mice, Inbred Strains | Rats, Inbred Strains | Pyrimidines - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Animals | Analgesics - chemical synthesis | Analgesics - chemistry | Benzimidazoles - pharmacology | Female | Mice | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Pyrimidines | Universities and colleges | Analgesics | Anti-inflammatory drugs | Analysis | Pharmacy
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 2017, Volume 35, Issue 2, pp. 157 - 165
Journal Article
Blood, ISSN 1528-0020, 2008, Volume 111, Issue 8, pp. 4022 - 4028
Journal Article
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2013, Volume 369, Issue 1, pp. 32 - 42
Ibrutinib inhibits Bruton's tyrosine kinase, a component of normal B-cell activation pathways. Ibrutinib produced responses in 71% of patients with refractory... 
MEDICINE, GENERAL & INTERNAL | BRUTONS TYROSINE KINASE | ACTIVATION | RITUXIMAB | B-CELL MALIGNANCIES | PCI-32765 | SURVIVAL SIGNALS | KAPPA-B | INHIBITOR | ANTIGEN RECEPTOR | FLUDARABINE | Recurrence | Pyrazoles - therapeutic use | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Pyrazoles - pharmacokinetics | Pyrazoles - adverse effects | Pyrazoles - pharmacology | Treatment Outcome | Pyrimidines - pharmacology | Remission Induction | Disease-Free Survival | Pyrimidines - therapeutic use | Pyrimidines - adverse effects | Pyrimidines - pharmacokinetics | Aged | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Protein-Tyrosine Kinases - antagonists & inhibitors | Antimitotic agents | Chronic lymphocytic leukemia | Care and treatment | Product development | Antineoplastic agents | Tyrosine | Cell proliferation | Pharmacodynamics | Chronic lymphatic leukemia | Cell survival | Leukemia | Diarrhea | Fatigue | Lymphatic leukemia | Kinases | Lymphoma | Bruton's tyrosine kinase | Patients | Risk factors | Cell adhesion & migration | Clonal deletion | Lymphocytes B | Respiratory tract diseases | Lymphomas | Pharmacokinetics | Lymphocytosis | Protein-tyrosine kinase | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 05/2018, Volume 26, Issue 9, pp. 2640 - 2650
[Display omitted] To combine the potency of trimetrexate (TMQ) or piritrexim (PTX) with the species selectivity of trimethoprim (TMP), target based design was... 
hDHFR | Pyrrolo[2,3-d]pyrimidines | Opportunistic infections | DHFR inhibitors | pjDHFR | Pneumocystis pneumonia | CHEMISTRY, MEDICINAL | VARIANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | CHEMISTRY, ORGANIC | CARINII | ADVERSE-REACTIONS | PROPHYLAXIS | PNEUMOCYSTIS-JIROVECII PNEUMONIA | RESISTANCE | MACROMOLECULAR CRYSTALLOGRAPHY | MUTATIONS | TRIMETHOPRIM-SULFAMETHOXAZOLE | Folic Acid Antagonists - chemistry | Species Specificity | Tetrahydrofolate Dehydrogenase - chemistry | Pyrimidines - chemical synthesis | Humans | Amino Acids - chemistry | Crystallography, X-Ray | Pyrimidines - chemistry | Pyrimidines - metabolism | Drug Design | Molecular Structure | Folic Acid Antagonists - chemical synthesis | Pyrroles - metabolism | Catalytic Domain | Enzyme Assays | Pyrimidines - pharmacology | Tetrahydrofolate Dehydrogenase - metabolism | Anti-Bacterial Agents - chemical synthesis | Sequence Homology, Amino Acid | Pyrroles - pharmacology | Folic Acid Antagonists - metabolism | Pyrroles - chemical synthesis | Hydrogen Bonding | Pneumocystis carinii - enzymology | Hydrophobic and Hydrophilic Interactions | Protein Binding | Pyrroles - chemistry | Anti-Bacterial Agents - pharmacology | Molecular Docking Simulation | Folic Acid Antagonists - pharmacology | Antiviral agents | Medical colleges | Pneumonia | Bacterial pneumonia | Crystals | Amino acids | Antibacterial agents | Highly active antiretroviral therapy | Pyrimidines | Analysis | Dihydrofolate reductase | Structure | Health aspects | opportunistic infections | 3-d]pyrimidines | pyrrolo
Journal Article
European journal of medicinal chemistry, ISSN 0223-5234, 2011, Volume 46, Issue 9, pp. 3690 - 3695
Journal Article
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2018, Volume 28, Issue 20, pp. 3356 - 3362
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2017, Volume 112, Issue 3, pp. 71a - 71a
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2017, Volume 112, Issue 3, pp. 460a - 460a
Journal Article
Acta pharmaceutica (Zagreb, Croatia), ISSN 1846-9558, 2017, Volume 67, Issue 3, pp. 275 - 292
Journal Article