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Talanta, ISSN 0039-9140, 09/2011, Volume 85, Issue 3, pp. 1500 - 1507
Pesticides residues in aquatic ecosystems are an environmental concern which requires efficient analytical methods. In this study, we proposed a generic method... 
Water | Fish | Sediments | Multiresidue analysis | LC–MS/MS | Pesticides | LC-MS/MS | CHEMISTRY, ANALYTICAL | PHARMACEUTICALS | TURKEY | QUECHERS METHOD | PRODUCTS | CHROMATOGRAPHY-MASS SPECTROMETRY | SAMPLES | TISSUES | RESIDUES | EXPOSURE | SOLID-PHASE EXTRACTION | Niacinamide - analogs & derivatives | Carbamates - isolation & purification | Naphthalenes - analysis | Oxazolidinones - analysis | Hydantoins - isolation & purification | Aminoimidazole Carboxamide - isolation & purification | Naphthalenes - isolation & purification | Pyrimidines - isolation & purification | Oxazolidinones - isolation & purification | Water Pollutants, Chemical - isolation & purification | Methacrylates - analysis | Niacinamide - isolation & purification | Thiophenes | Fishes | Geologic Sediments - chemistry | Pesticide Residues - analysis | Chemical Fractionation - methods | Isoxazoles - analysis | Niacinamide - analysis | Pesticide Residues - isolation & purification | Carbamates - analysis | Tandem Mass Spectrometry - methods | Pyrimidines - analysis | Reproducibility of Results | Methacrylates - isolation & purification | Phenylurea Compounds - isolation & purification | Environmental Monitoring - methods | Strobilurins | Isoxazoles - isolation & purification | Quinoxalines | Aminoimidazole Carboxamide - analysis | Sulfonylurea Compounds - isolation & purification | Pesticides - analysis | Phenylurea Compounds - analysis | Sulfonylurea Compounds - analysis | Water Pollutants, Chemical - analysis | Benzimidazoles - analysis | Acetamides - isolation & purification | Animals | Pesticides - isolation & purification | Aminoimidazole Carboxamide - analogs & derivatives | Propionates | Solid Phase Extraction - methods | Muscles - chemistry | Acetamides - analysis | Chromatography, Liquid - methods | Hydantoins - analysis | Benzimidazoles - isolation & purification | Liquid chromatography | Mass spectrometry | Analysis | Methods | Sediments (Geology) | Analytical chemistry | Chemical Sciences
Journal Article
Circulation, ISSN 0009-7322, 02/2014, Volume 129, Issue 6, pp. 635 - 642
Journal Article
Circulation, ISSN 0009-7322, 03/2010, Volume 121, Issue 9, pp. 1069 - 1077
Background-Statin therapy in women without cardiovascular disease (CVD) is controversial, given the insufficient evidence of benefit. We analyzed sex-specific... 
Prevention | Women | Lipids | Meta-analysis | LOVASTATIN | lipids | CARDIAC & CARDIOVASCULAR SYSTEMS | meta-analysis | RANDOMIZED CONTROLLED-TRIAL | HYPERTENSIVE PATIENTS | AFCAPS/TEXCAPS | INDIVIDUALS | DENSITY-LIPOPROTEIN CHOLESTEROL | MEN | PERIPHERAL VASCULAR DISEASE | PRAVASTATIN | OUTCOMES | CORONARY-HEART-DISEASE | HEMATOLOGY | prevention | women | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Follow-Up Studies | Humans | Middle Aged | Male | Risk | Fluorobenzenes - administration & dosage | Early Termination of Clinical Trials | Dyslipidemias - blood | Cholesterol, LDL - blood | Female | Stroke - epidemiology | Muscular Diseases - chemically induced | C-Reactive Protein - analysis | Myocardial Ischemia - epidemiology | Dyslipidemias - drug therapy | Stroke - prevention & control | Double-Blind Method | Comorbidity | Pyrimidines - administration & dosage | Risk Factors | Proportional Hazards Models | Myocardial Ischemia - prevention & control | Rosuvastatin Calcium | Treatment Outcome | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Sulfonamides - therapeutic use | Pyrimidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Pyrimidines - adverse effects | Sex Factors | Sulfonamides - adverse effects | Aged | Fluorobenzenes - adverse effects | Fluorobenzenes - therapeutic use | Myocardial Ischemia - surgery | Sulfonamides - administration & dosage | Demographic aspects | Sex factors in disease | Rosuvastatin | Dosage and administration | Research | Cardiovascular diseases
Journal Article
1983, 3rd ed., ISBN 3527260439, v.
Book
Annals of the Rheumatic Diseases, ISSN 0003-4967, 07/2017, Volume 76, Issue 7, pp. 1253 - 1262
ObjectivesTofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). We report an integrated safety summary of tofacitinib... 
Cardiovascular Disease | Infections | Treatment | Tuberculosis | Rheumatoid Arthritis | JAK INHIBITOR | MODIFYING ANTIRHEUMATIC DRUGS | JANUS KINASE INHIBITOR | INADEQUATE RESPONSE | HERPES-ZOSTER | ANTI-TNF THERAPY | GASTROINTESTINAL PERFORATIONS | OPPORTUNISTIC INFECTIONS | RHEUMATOLOGY | NECROSIS FACTOR THERAPY | SERIOUS INFECTIONS | Tuberculosis - epidemiology | Herpes Zoster - etiology | Neoplasms - etiology | Humans | Middle Aged | Tuberculosis - etiology | Male | Protein Kinase Inhibitors - adverse effects | Infection - etiology | Incidence | Opportunistic Infections - etiology | Young Adult | Infection - epidemiology | Time Factors | Arthritis, Rheumatoid - drug therapy | Aged, 80 and over | Pyrroles - adverse effects | Adult | Female | Opportunistic Infections - immunology | Herpes Zoster - epidemiology | Herpes Zoster - immunology | Opportunistic Infections - epidemiology | Infection - immunology | Clinical Trials as Topic | Tuberculosis - immunology | Neoplasms - immunology | Piperidines - adverse effects | Adolescent | Pyrimidines - adverse effects | Aged | Immunocompromised Host | Neoplasms - epidemiology | Clinical trials | Care and treatment | Research | Tofacitinib | Rheumatoid arthritis | Analysis | Herpes zoster | Melanoma | Data processing | Cancer therapies | Inflammatory diseases | Data bases | Skin cancer | Studies | Algorithms | Surveillance | Data collection | Janus kinase | Chronic obstructive pulmonary disease | Health risk assessment | Clinical and Epidemiological Research | 1506
Journal Article
Lancet, The, ISSN 0140-6736, 2012, Volume 380, Issue 9841, pp. 565 - 571
Journal Article
Biomedical Chromatography, ISSN 0269-3879, 03/2006, Volume 20, Issue 3, pp. 282 - 293
A specific, accurate, precise and reproducible high‐performance liquid chromatographic (HPLC) method was developed and validated for the simultaneous... 
hyperlipidemia | metabolism | HPLC analysis | statins | Metabolism | Hyperlipidemia | Statins | HUMAN-SERUM | CHEMISTRY, ANALYTICAL | FAMILIAL HYPERCHOLESTEROLEMIA | COENZYME-A-REDUCTASE | HUMAN PLASMA | HYDROXY ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | LOW-DENSITY-LIPOPROTEIN | BIOTRANSFORMATION PRODUCTS | TANDEM MASS-SPECTROMETRY | PERFORMANCE LIQUID-CHROMATOGRAPHY | PHARMACOLOGY & PHARMACY | CORONARY-HEART-DISEASE | Fluorobenzenes - pharmacokinetics | Gas Chromatography-Mass Spectrometry | Pyrroles - pharmacokinetics | Lovastatin - pharmacology | Heptanoic Acids - pharmacokinetics | Humans | Chromatography, High Pressure Liquid | Simvastatin - pharmacology | Fluorobenzenes - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Lovastatin - analysis | Heptanoic Acids - analysis | Heptanoic Acids - pharmacology | Pravastatin - pharmacology | Pyrimidines - analysis | Sulfonamides - analysis | Lovastatin - pharmacokinetics | Pyrroles - analysis | Rosuvastatin Calcium | Pyrimidines - pharmacology | Simvastatin - pharmacokinetics | Sulfonamides - pharmacology | Sulfonamides - pharmacokinetics | Pravastatin - analysis | Atorvastatin Calcium | Pyrroles - pharmacology | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - analysis | Pharmaceutical Preparations - chemistry | Pyrimidines - pharmacokinetics | Fluorobenzenes - analysis | Pravastatin - pharmacokinetics | Simvastatin - analysis
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2011, Volume 54, Issue 13, pp. 4462 - 4473
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2010, Volume 18, Issue 15, pp. 5738 - 5748
Here, we present a structural comparison of the important and similar interactions necessary for Gleevec®, Nexavar®, and BIRB-796 to bind to their respective... 
Allosteric structure based drug design kinase type II | CHEMISTRY, MEDICINAL | PROTEIN | C-ABL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | SORAFENIB | CANCER | P38 MAP KINASE | HEPATOCELLULAR-CARCINOMA | MELANOMA | BRAF MUTATIONS | IMATINIB | B-RAF | Niacinamide - analogs & derivatives | Mitogen-Activated Protein Kinase 14 - antagonists & inhibitors | Proto-Oncogene Proteins c-abl - antagonists & inhibitors | Pyridines - chemistry | Allosteric Regulation | Antineoplastic Agents - chemical synthesis | Crystallography, X-Ray | Phenylurea Compounds | Piperazines - chemistry | Pyrimidines - chemistry | Benzenesulfonates - pharmacology | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Mitogen-Activated Protein Kinase 14 - metabolism | Computer Simulation | Drug Design | Antineoplastic Agents - pharmacology | Oligopeptides - chemistry | Proto-Oncogene Proteins B-raf - metabolism | Pyrazoles - pharmacology | Naphthalenes - chemistry | Amino Acid Sequence | Protein Kinase Inhibitors - chemical synthesis | Catalytic Domain | Pyrimidines - pharmacology | Antineoplastic Agents - chemistry | Imatinib Mesylate | Piperazines - pharmacology | Naphthalenes - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Benzenesulfonates - chemistry | Hydrogen Bonding | Proto-Oncogene Proteins c-abl - metabolism | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Benzamides | Adenosine Triphosphate - chemistry | Antimitotic agents | Chemical properties | Antineoplastic agents | Pharmacy | Analysis | Index Medicus
Journal Article
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 2/2009, Volume 48, Issue 3, pp. 265 - 273
Background. With use of data from the Prospective Antifungal Therapy (PATH) Alliance registry, we performed this multicenter, prospective, observational study... 
Antifungals | Aspergillus | Health outcomes | Mortality |